$84 Cheap flight deals from Houston (HOU) to La Mesa (SAN)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Houston to La Mesa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $84 One Way, $161 Round Trip from Houston to La Mesa
Prices starting at $161 for return flights and $84 for one-way flights to La Mesa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
La Mesa economy flight packages
Margaritaville Hotel San Diego Gaslamp Quarter
Oct 26 - Oct 30
Houston (HOU) to San Diego (SAN)
Reviewed on Sep 6, 2026
Fairmont Grand Del Mar
Oct 10 - Oct 14
Houston (IAH) to San Diego (SAN)
San Diego (SAN) to Houston (IAH)
Reviewed on Aug 30, 2026
More About Flying To La Mesa from Houston
Route Information for Flights from Houston to La Mesa
Origin Airport IATA Code | HOU |
|---|---|
Destination Airport IATA Code | SAN |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Houston to La Mesa
It has never been easier to find cheap Houston to La Mesa flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.
Plan Your Houston to La Mesa Flights on the Go
Orbitz offers cutting-edge mobile tools that let you search and book flights anywhere. All you need is a smartphone or mobile device to find discounts on flights from Houston to La Mesa. Use the app to check to make sure your flight is on time or book a last-minute cheap hotel room.
Get the Best Deals on Houston to La Mesa Flights
Finding great deals on flights from Houston to La Mesa is a snap with Orbitz. With our guaranteed low prices, you don’t have to worry if you are getting the best prices on air tickets, hotels, and cruises. And with all that money you saved, you can enjoy your La Mesa vacation even more.
Pile Up Miles With Discount Air Tickets
Not only can you find great bargains on Houston to La Mesa flights, but you can rack up frequent flyer miles on the flights too. Enter your frequent flyer number on qualified flights when booking for Orbitz to see the miles pile up in your account.
Flight Alerts Keep You Informed
Stay on top of the latest updates for flights from Houston to La Mesa. We send you free email and mobile alerts to keep you informed about delays to Houston to La Mesa flights.
Flights from Houston
- Houston to New York
- Houston to Chicago
- Houston to Orlando
- Houston to Los Angeles
- Houston to New Orleans
- Houston to Dallas
- Houston to Washington
- Houston to London
- Houston to Toronto
- Houston to Phoenix
- Houston to Rome
- Houston to Paris
- Houston to Detroit
- Houston to Indianapolis
- Houston to San Francisco
- Houston to Beijing
- Houston to Kansas City
- Houston to Montreal
- Houston to Hartford
- Houston to Edmonton
More Destinations
- Flights from Green Bay to Lemon Grove
- Flights from Boston to Lemon Grove
- Flights from Cleveland to Lemon Grove
- Flights from Denver to Lemon Grove
- Flights from Miami to Lemon Grove
- Flights from San Antonio to Lemon Grove
- Flights from San Francisco to Lemon Grove
- Flights from Seattle to Lemon Grove
- Flights from Washington to Lemon Grove
- Flights from Stockton to Lemon Grove
- Flights from Princeton to Lemon Grove
- Flights from Newport News to Lemon Grove
- Flights from Abilene (ABI) to San Diego (MYF)
- Flights from Armidale (ARM) to San Diego (MYF)
- Flights from Bali (BAJ) to San Diego (MYF)
- Flights from Bridgetown (BGI) to San Diego (MYF)
- Flights from Boa Vista Island (BVC) to San Diego (MYF)
- Flights from Chateauroux (CHR) to San Diego (MYF)
- Flights from Cairns (CNS) to San Diego (MYF)
- Flights from Corvallis (CVO) to San Diego (MYF)
- Flights from Kiritimati (CXI) to San Diego (MYF)
- Flights from Da Nang (DAD) to San Diego (MYF)
- Flights from Dothan (DHN) to San Diego (MYF)
- Flights from Elko (EKO) to San Diego (MYF)
- Flights from Florencia (FLA) to San Diego (MYF)
- Flights from Hayward (HWD) to San Diego (MYF)
- Flights from Wichita (ICT) to San Diego (MYF)
- Flights from Kaitaia (KAT) to San Diego (MYF)
- Flights from Kyiv (KBP) to San Diego (MYF)
- Flights from Karratha (KTA) to San Diego (MYF)
- Flights from Seattle (LKE) to San Diego (MYF)
- Flights from Luang Prabang (LPQ) to San Diego (MYF)
- Flights from Monteagudo (MHW) to San Diego (MYF)
- Flights from Minneapolis (MSP) to San Diego (MYF)
- Flights from Maastricht (MST) to San Diego (MYF)
- Flights from Port Lincoln (PLO) to San Diego (MYF)
- Flights from Papeete (PPT) to San Diego (MYF)
- Flights from Rangiroa (RGI) to San Diego (MYF)
- Flights from Rodrigues Island (RRG) to San Diego (MYF)
- Flights from São José do Rio Preto (SJP) to San Diego (MYF)
- Flights from Orange County (SNA) to San Diego (MYF)
- Flights from Southampton (SOU) to San Diego (MYF)
- Flights from Stavropol (STW) to San Diego (MYF)
- Flights from Takapoto (TKP) to San Diego (MYF)
- Flights from Samui Intl. Airport (USM) to San Diego (MYF)
- Flights from Visakhapatnam (VTZ) to San Diego (MYF)
- Flights from Christmas Island (XCH) to San Diego (MYF)
- Flights from Timmins (YTS) to San Diego (MYF)
- Flights from Beef Island to El Cajon
- Flights from Fairbanks to El Cajon
- Flights from Guayaquil to El Cajon
- Flights from Houayxay to El Cajon
- Flights from Sitia to El Cajon
- Flights from Beijing to El Cajon
- Flights from Cincinnati to El Cajon
- Flights from Las Vegas to El Cajon
- Flights from Los Angeles to El Cajon
- Flights from Phoenix to El Cajon
- Flights from San Francisco to El Cajon
- Flights from Palmerston North to El Cajon
- Flights from Santa Maria to El Cajon
- Flights from Sainte Marie to El Cajon
- Flights from Saratov to El Cajon
- Flights from San Diego to El Cajon
- Flights from Castries to El Cajon
- Flights from Tarawa to El Cajon
- Flights from Brandon to El Cajon
- Flights from Sohar to El Cajon
- Flights from Dubrovnik to El Cajon
- Flights from Huong Thuy to El Cajon
- Flights from San Andrés to El Cajon
- Flights from Zivinice to El Cajon
- Flights from Myrtle Beach to El Cajon
- Flights from Tulsa to El Cajon
- Flights from Grand Rapids to El Cajon
- Flights from Asheville to El Cajon
- Flights from Murrieta to El Cajon
- Flights from Jaipur District to El Cajon
- Flights from Recife to El Cajon
- Flights from Kochi to El Cajon
- Flights from Huntsville to El Cajon
- Flights from Zhengzhou to El Cajon
- Flights from Depok to El Cajon
- Flights from Artem to El Cajon
- Flights from Kaukura to El Cajon
- Flights from San José del Cabo to El Cajon
- Flights from Merzifon to El Cajon
- Flights from Atlanta to San Diego
- Flights from Boston to San Diego
- Flights from Chicago to San Diego
- Flights from Dallas to San Diego
- Flights from Houston to San Diego
- Flights from Las Vegas to San Diego
- Flights from New York to San Diego
- Flights from Phoenix to San Diego
- Flights from Portland to San Diego
- Flights from Salt Lake City to San Diego
- Flights from Sacramento to San Diego
- Flights from San Jose to San Diego
- Flights from Brasilia (BSB) to San Diego (SEE)
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.