Hotels with Air Conditioning in Orangeburg
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Orangeburg Hotels with Air Conditioning

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
Guests of Baymont by Wyndham Orangeburg North enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this adults-only hotel include coffee/tea in a common area, express check-out, and laundry facilities.
Pool
Breakfast included

Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Free Cancellation
Reserve now, pay when you stay
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.
Pool
Breakfast included

Comfort Inn & Suites
746 Citadel Rd, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
At Comfort Inn & Suites, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include a business center, a meeting room, and express check-out.
Pool
Breakfast included

Comfort Inn & Suites Santee
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Spark by Hilton Orangeburg
731 Citadel Road, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a meeting room, and express check-out.
Pool
Breakfast included

Days Inn by Wyndham Orangeburg
3691 Saint Matthews Rd, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
Guests of Days Inn by Wyndham Orangeburg enjoy free WiFi in public areas, a business center, and express check-out. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a vending machine.
Breakfast included
Pet friendly

Econo Lodge
9112 Old 6 Highway, Santee, SC
Free Cancellation
Reserve now, pay when you stay
Econo Lodge features free WiFi in public areas and barbecue grills. There's free parking if you drive. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This hotel also has a garden.
Pet friendly
Parking included

Fairfield Inn by Marriott Orangeburg
663 Citadel Road, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
At Fairfield Inn by Marriott Orangeburg, guests have access to a gym, free WiFi in public areas, and a 24-hour business center. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-in.
Pool
Breakfast included

Hampton Inn & Suites Orangeburg
749 Citadel Road, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
Guests of Hampton Inn & Suites Orangeburg have access to an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and express check-in.
Pool
Breakfast included

Holiday Inn Express & Suites Orangeburg by IHG
118 Sleep Inn Road, Orangeburg, SC
Free Cancellation
At Holiday Inn Express & Suites Orangeburg by IHG, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-out.
Pool
Breakfast included

Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Free Cancellation
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.
Pool
Pet friendly

Baymont by Wyndham Santee
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Breakfast included
Pet friendly

Days Inn by Wyndham Orangeburg South
3402 Five Chop Rd, Rr 2 Box 215, Orangeburg, SC
Guests of Days Inn by Wyndham Orangeburg South enjoy free WiFi in public areas, free newspapers, and laundry facilities. If you decide to drive, there's free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Pool
Breakfast included

Quality Inn & Suites
3671 Saint Matthews Rd, Building A, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
Quality Inn & Suites features free WiFi in public areas, coffee in a common area, and laundry facilities. Free parking is included with your stay. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a gift shop and barbecue grills.
Breakfast included
Pet friendly

Red Roof Inn Santee
9091 Old Hwy 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.
Breakfast included
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Orangeburg hotels essential information
Accommodation | 221 hotels |
---|---|
Lowest Price | |
Highest Price | |
Popular hotels | Baymont by Wyndham Orangeburg North, Best Western Plus Santee Inn, Comfort Inn & Suites, Comfort Inn & Suites Santee, Spark by Hilton Orangeburg, Days Inn by Wyndham Orangeburg, Econo Lodge, Fairfield Inn by Marriott Orangeburg, Hampton Inn & Suites Orangeburg, Holiday Inn Express & Suites Orangeburg by IHG, Holiday Inn Santee by IHG, Baymont by Wyndham Santee, Days Inn by Wyndham Orangeburg South, Quality Inn & Suites, Red Roof Inn Santee |
Recent Hotels with Air Conditioning Reviews

Holiday Inn Express & Suites Orangeburg by IHG
5/5 Excellent
"Staff truly cared about the hotel and guests. Chef is doing a great job, food was fresh and hot. "
A verified traveler from Ferrisburgh stayed at Holiday Inn Express & Suites Orangeburg by IHG
Posted 2 days ago