Business Hotels in Orangeburg, SC

Guests of Baymont by Wyndham Orangeburg North enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this adults-only hotel include coffee/tea in a common area, express check-out, and laundry facilities.

At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.

Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, express check-out, and a terrace.

Guests of Hampton Inn & Suites Orangeburg have access to an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and express check-in.

Econo Lodge Santee features free WiFi in public areas and barbecue grills. There's free parking if you drive. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This hotel also has a garden.

Southern Lodge features free WiFi in public areas, a business center, and coffee in a common area. You can take advantage of free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a TV in a common area.

Super 8 by Wyndham, Orangeburg features free WiFi in public areas, a business center, and coffee in a common area. If you drive, put free parking to good use. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.

Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.

At Comfort Inn & Suites Orangeburg, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with securing valuables, tours or tickets, and dry cleaning/laundry. Additional amenities include a business center, a meeting room, and express check-out.

Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.

Guests of Days Inn by Wyndham Orangeburg enjoy free WiFi in public areas, a business center, and express check-out. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a vending machine.

At Fairfield Inn by Marriott Orangeburg, guests have access to a gym, free WiFi in public areas, and a 24-hour business center. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-in.

At Holiday Inn Express & Suites Orangeburg by IHG, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and express check-out.

At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.

At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.