Hotels in South Central Houston
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Tomorrow night
Check prices in South Central Houston for tomorrow night, Jun 20 - Jun 21Featured Hotels in South Central Houston

Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Free Cancellation
Reserve now, pay when you stay
2.74 mi from South Central Houston
The price is $117 total per night
$117 total
per night
Jul 5 - Jul 6
Guests staying at Hilton Houston Plaza/Medical Center enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 20 per day. Multilingual staff at the front desk are standing by 24/7 to help with concierge services, securing valuables, and dry cleaning/laundry. Other amenities at this luxury hotel include meeting rooms, conference space, and coffee/tea in a common area.
Pool
Free WiFi

Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Free Cancellation
Reserve now, pay when you stay
1.66 mi from South Central Houston
The price is $279 total per night
$279 total
per night
Jul 11 - Jul 12
Hotel Zaza Houston Museum District features a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for USD 60 per night, and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this luxury hotel include a sauna, free WiFi in public areas, and conference space.
Pool
Spa

InterContinental Houston by IHG
6750 Main St Houston TX
2.89 mi from South Central Houston
The price is $215 total per night
$215 total
per night
Jul 18 - Jul 19
Guests of InterContinental Houston by IHG have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Parking is available for USD 40 per day (USD 53 per day for valet parking), and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and concierge services. Additional amenities include conference space, a 24-hour business center, and express check-out.
Pool
Pet friendly

The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
2.65 mi from South Central Houston
The price is $167 total per night
$167 total
per night
Jul 5 - Jul 6
At The Westin Houston Medical Center/Museum District, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 54 per night. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, concierge services, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Pet friendly

Sentral Forme Houston
5501 La Branch Street Houston TX
Free Cancellation
Reserve now, pay when you stay
1.34 mi from South Central Houston
The price is $227 total per night
$227 total
per night
Jul 7 - Jul 8
Built in 2023, the brand new Sentral Forme Houston offers an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 25 per day. Front-desk staff are standing by 24/7 to assist with any requests. Other amenities at this luxury aparthotel include a hot tub, meeting rooms, and express check-in.
Pool
Hot Tub

Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
Free Cancellation
Reserve now, pay when you stay
2.89 mi from South Central Houston
The price is $98 total per night
$98 total
per night
Jun 21 - Jun 22
Guests of Extended Stay America Suites Houston Med Ctr Braeswood Bl have access to an outdoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include conference space, coffee/tea in a common area, and laundry facilities.
Pool
Breakfast included

Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
Free Cancellation
Reserve now, pay when you stay
0.95 mi from South Central Houston
The price is $103 total per night
$103 total
per night
Jul 1 - Jul 2
Downtowner Inns - Houston Downtown features free WiFi in public areas and a vending machine. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations.
Breakfast included
Parking included

DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
Free Cancellation
Reserve now, pay when you stay
2.91 mi from South Central Houston
The price is $143 total per night
$143 total
per night
Jul 5 - Jul 6
At DoubleTree by Hilton Houston Medical Center Hotel & Suites, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, self parking is USD 25.00 per night, and there's also a free area shuttle. The 24-hour front desk has multilingual staff ready to assist with securing valuables and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Pet friendly

Houston Marriott Medical Center/Museum District
6580 Fannin Street Houston TX
Free Cancellation
Reserve now, pay when you stay
2.61 mi from South Central Houston
The price is $221 total per night
$221 total
per night
Jul 5 - Jul 6
Guests of Houston Marriott Medical Center/Museum District enjoy a 24-hour gym, free WiFi in public areas, and a conference center. Valet parking is available for USD 49 per day, and there's also a free area shuttle. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, express check-in, and express check-out.
Pet friendly
Free WiFi
Don't see what you're looking for?
See all available properties in South Central Houston
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Central Houston hotels essential information
Accommodation | 1,214 hotels |
|---|---|
Lowest Price | $98 |
Highest Price | $279 |
Popular hotels | Hilton Houston Plaza/Medical Center, Hotel Zaza Houston Museum District, InterContinental Houston by IHG, The Westin Houston Medical Center/Museum District, Sentral Forme Houston, Extended Stay America Suites Houston Med Ctr Braeswood Bl, Downtowner Inns - Houston Downtown, DoubleTree by Hilton Houston Medical Center Hotel & Suites, Houston Marriott Medical Center/Museum District |
Popular places to visit

Rice University
4.5/5(362 reviews)
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's fascinating museums and acclaimed art scene.

University of Houston
4/5(397 reviews)
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the fascinating museums and acclaimed theater scene in this vibrant area.

Houston Zoo
4.5/5(1,019 reviews)
Why not visit the native and exotic animals who call Houston Zoo home during your trip to Houston? Experience the area's fascinating museums and acclaimed art scene.
Recent Reviews

Sentral Forme Houston
5/5 Excellent
"It was super nice and reasonably priced, even for World Cup prices"
A verified traveler stayed at Sentral Forme Houston
Posted 2 hours ago
More to Explore
- Hotels near George R. Brown Convention Center
- Hotels in Downtown Houston
- Hotels with Free Airport Shuttle in Houston
- Flights to Houston
- Hotels in Houston Museum District
- Hotels near Rice University
- Hotels near Houston Natural Science Museum
- Hotels near NRG Stadium
- Hotels near MD Anderson Cancer Center
- Hotels in Texas Medical Center
- Hotels near Toyota Center
- Cheap Hotels in Houston
- Hotels near Houston Zoo
- Houston vacations
- Hotels near University of Houston
- Hotels near Texas Southern University
- Hotels in Houston
- Car rentals in Houston
- Hotels in Midtown


