Book 2 Star Hotels in Byron
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Featured Byron 2 Stars Hotels

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.14 mi from city center
$94 nightly
The price is $108 total per night
$108 total
May 17 - May 18
Total with taxes and fees
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's features an indoor pool, a children's pool, and a gym. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Other amenities at this family-friendly hotel include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.24 mi from city center
$94 nightly
The price is $108 total per night
$108 total
May 23 - May 24
Total with taxes and fees
Guests staying at SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 7 per night. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a hot tub, a 24-hour business center, and a computer station.
Pool
Hot Tub

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Free Cancellation
8.29 mi from city center
$117 nightly
The price is $134 total per night
$134 total
May 22 - May 23
Total with taxes and fees
At EVEN Hotel Rochester - Mayo Clinic Area by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 20 per night. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.85 mi from city center
$114 nightly
The price is $131 total per night
$131 total
May 17 - May 18
Total with taxes and fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area features an indoor pool, a children's pool, and a 24-hour gym. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 30.00 per room one-way. The 24-hour front desk has multilingual staff ready to assist with luggage storage, concierge services, and dry cleaning/laundry. Other amenities at this golf hotel include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.84 mi from city center
$132 nightly
The price is $152 total per night
$152 total
May 13 - May 14
Total with taxes and fees
Guests staying at Kahler Inn and Suites - Mayo Clinic Area enjoy an indoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 15 per night. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a fireplace in the lobby, and a convenience store.
Pool
Breakfast included

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.95 mi from city center
$127 nightly
The price is $146 total per night
$146 total
May 15 - May 16
Total with taxes and fees
At Kahler Grand Hotel, guests enjoy features like an indoor pool, a 24-hour gym, and a sauna. Valet parking is offered for USD 34.00 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Free Cancellation
Reserve now, pay when you stay
8.96 mi from city center
$139 nightly
The price is $160 total per night
$160 total
May 31 - Jun 1
Total with taxes and fees
Guests staying at Hyatt House Rochester/Mayo Clinic Area enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 16 per day, and there's also a free area shuttle. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Free Cancellation
Reserve now, pay when you stay
9.28 mi from city center
$76 nightly
The price is $88 total per night
$88 total
May 31 - Jun 1
Total with taxes and fees
AmericInn by Wyndham Rochester Near Mayo Clinic features a full-service spa, an indoor pool, and a children's pool. You can take advantage of free parking, along with an area shuttle. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Other amenities at this spa hotel include a 24-hour gym, free WiFi in public areas, and a hot tub.
Pool
Hot Tub

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Free Cancellation
9.12 mi from city center
$93 nightly
The price is $107 total per night
$107 total
May 23 - May 24
Total with taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG offers a gym, a rooftop terrace, and free WiFi in public areas. Self parking is available for USD 16.00 per night. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pet friendly
Free WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Byron hotels essential information
Accommodation | 392 hotels |
|---|---|
Lowest Price | $88 |
Highest Price | $160 |
Popular hotels | Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hyatt House Rochester/Mayo Clinic Area, AmericInn by Wyndham Rochester Near Mayo Clinic, Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area, EVEN Hotel Rochester - Mayo Clinic Area by IHG, SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Best Western Rochester Hotel Mayo Clinic Area/St. Mary's |
Recent Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic
1/5 Terrible
"This hotel is NOT for anyone using a wheelchair. Although it is advertised as wheelchair accessible, it is not easy. The only automatic door was the front lobby entrance, side doors did not have easy access and the threshold of these doors were nearly impossible to get over. Our room was on the first floor. However there was an very long incline which was very difficult to push a wheelchair up. Two other guests had to help me push to get to our room. The desk clerk laughed at me when I asked if there was any other entrance to use that didn't involve climbing a hill. Yes, there was a side entrance. It still had an incline just not as long. There was not a railing to hang onto along the sidewalk and I nearly lost control and crashed the wheelchair into a dumpster at the bottom of the incline. The overflowing dumpsters may have cushioned the impact had there been one. The toilet in our room was ridiculously low making it extremely difficult to get on and off and there were no any grab bars in the shower, making a fall risk very real. At breakfast they had instant oatmeal but not a microwave to use to prepare. When asked if there was a microwave to use, the kitchen staff said in a huff that there was not a microwave for guest use but that she would do it for us. She had some illness which made her cough and hack horribly so even though she heated it up, we didn't eat it due to fear of illness. We have many upcoming appts at Mayo but we will NOT stay here again!"
A verified traveler stayed at AmericInn by Wyndham Rochester Near Mayo Clinic
Posted 1 hour ago
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