Hotels in Southern Illinois

Search over 1,224 hotels from $60

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top Rated Southern Illinois Hotels

Don't see what you're looking for?
See all available properties in Southern Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Illinois attractions

Cheap Southern Illinois hotels options

    Motel 6 Caseyville, IL - Caseyville Il

    Motel 6 Caseyville, IL - Caseyville Il

    2431 Old Country Inn Dr Caseyville IL
    $59 nightly
    The price is $67 total per night from Nov 14 to Nov 15
    $67 total
    Nov 14 - Nov 15
    Total with taxes and fees
    Days Inn by Wyndham Charleston

    Days Inn by Wyndham Charleston

    810 West Lincoln Avenue Charleston IL
    $82 nightly
    The price is $91 total per night from Nov 29 to Nov 30
    $91 total
    Nov 29 - Nov 30
    Total with taxes and fees
    Super 8 by Wyndham Marion

    Super 8 by Wyndham Marion

    2601 Vernell Rd Marion IL
    $74 nightly
    The price is $89 total per night from Nov 15 to Nov 16
    $89 total
    Nov 15 - Nov 16
    Total with taxes and fees
    7.6/10 Good! (1,000 reviews)
    Americas Best Value Inn West Frankfort

    Americas Best Value Inn West Frankfort

    1001 Factory Outlet Blvd West Frankfort IL
    $78 nightly
    The price is $87 total per night from Nov 14 to Nov 15
    $87 total
    Nov 14 - Nov 15
    Total with taxes and fees
    7.6/10 Good! (541 reviews)
    Super 8 by Wyndham Belleville St. Louis Area

    Super 8 by Wyndham Belleville St. Louis Area

    600 East Main Street Belleville IL
    $65 nightly
    The price is $74 total per night from Nov 19 to Nov 20
    $74 total
    Nov 19 - Nov 20
    Total with taxes and fees
    Americas Best Value Inn Mount Vernon

    Americas Best Value Inn Mount Vernon

    222 South 44th Street Mount Vernon IL
    $72 nightly
    The price is $82 total per night from Nov 15 to Nov 16
    $82 total
    Nov 15 - Nov 16
    Total with taxes and fees

Southern Illinois hotels essential information

Accommodation
1,224 hotels
Lowest Price
$60
Highest Price
$125
Popular hotels
Drury Plaza Hotel Mt. Vernon, Drury Inn & Suites St. Louis Fairview Heights, Baymont by Wyndham Effingham, Drury Inn & Suites St. Louis O'Fallon, IL, Best Western Delta Inn, Motel 6 Caseyville, IL - Caseyville Il, Super 8 by Wyndham O'Fallon, Quality Inn & Suites Metropolis I-24, Ramada by Wyndham Effingham, Comfort Inn Edwardsville - St. Louis, Holiday Inn Express Metropolis by IHG, Drury Inn & Suites Marion

Recent Reviews

More to Explore