Hotels in South Central Houston

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Sep 21 - Sep 22
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Featured Hotels in South Central Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
1.69 mi from South Central Houston
The price is $263 per night
$263
per night
Oct 4 - Oct 5
Hotel Zaza Houston Museum District features a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for USD 45 per night, and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this luxury aparthotel include a sauna, a rooftop terrace, and free WiFi in public areas.
InterContinental Houston, an IHG Hotel

InterContinental Houston, an IHG Hotel

4 out of 5
6750 Main St, Houston, TX
Free Cancellation
2.89 mi from South Central Houston
The price is $170 per night
$170
per night
Sep 29 - Sep 30
Built in 2018, the brand new InterContinental Houston, an IHG Hotel offers an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 39 per day. Front-desk staff can answer questions 24/7, and assist with securing valuables, concierge services, and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

3.5 out of 5
6633 Travis St, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.72 mi from South Central Houston
The price is $107 per night
$107
per night
Oct 22 - Oct 23
Guests staying at Hilton Houston Plaza/Medical Center enjoy a gym, a rooftop terrace, and free WiFi in public areas. Self parking is available for USD 20 per night. Multilingual staff at the front desk are standing by 24/7 to help with concierge services, luggage storage, and securing valuables. Additional amenities include conference space, a 24-hour business center, and a seasonal outdoor pool.
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.64 mi from South Central Houston
The price is $179 per night
$179
per night
Oct 7 - Oct 8
Built in 2019, the brand new The Westin Houston Medical Center/Museum District offers an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 42 per night. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, concierge services, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include conference space, a business center, and coffee/tea in a common area.
SureStay Plus Hotel by Best Western Houston Medical Center

SureStay Plus Hotel by Best Western Houston Medical Center

2.5 out of 5
6700 Main Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.82 mi from South Central Houston
The price is $126 per night
$126
per night
Oct 7 - Oct 8
At SureStay Plus Hotel by Best Western Houston Medical Center, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. You can take advantage of free parking, along with a free area shuttle. The 24-hour front desk has multilingual staff ready to assist with securing valuables and concierge services. Additional amenities include a 24-hour business center, express check-in, and express check-out.
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.61 mi from South Central Houston
The price is $170 per night
$170
per night
Oct 7 - Oct 8
At Houston Marriott Medical Center/Museum District, guests have access to a 24-hour gym, free WiFi in public areas, and a spa tub. Valet parking is available for USD 42 per day, and there's also a free area shuttle. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a conference center, a business center, and express check-in.
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.91 mi from South Central Houston
The price is $122 per night
$122
per night
Oct 5 - Oct 6
At DoubleTree by Hilton Houston Medical Center Hotel & Suites, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 20 per day, and there's also a free area shuttle. Multilingual staff at the 24-hour front desk can assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd, Houston, TX
Free Cancellation
Reserve now, pay when you stay
2.93 mi from South Central Houston
The price is $74 per night
$74
per night
Oct 5 - Oct 6
At Extended Stay America Suites Houston Med Ctr Braeswood Bl, guests have access to a gym, free WiFi in public areas, and conference space. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and laundry facilities.
Sonder The Hampstead

Sonder The Hampstead

3.5 out of 5
1508 Blodgett Street, Houston, TX
1.04 mi from South Central Houston
The price is $161 per night
$161
per night
Oct 22 - Oct 23
Guests of Sonder The Hampstead enjoy features like free WiFi in public areas. Self parking is offered for USD 15 per night. Helpful staff is there to provide concierge services, as well as offer insight about the area.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Central Houston Long Term & Extended Stay Hotels

Luxury Hotels in South Central Houston

    SpringHill Suites Houston Medical Center/NRG Park

    SpringHill Suites Houston Medical Center/NRG Park

    1400 Old Spanish Trl, Houston, TX
    The price is $144 per night from Sep 27 to Sep 28
    $144
    per night
    Sep 27 - Sep 28
    8.8/10 Excellent! (1,109 reviews)
    Ramada by Wyndham Houston Intercontinental Airport East

    Ramada by Wyndham Houston Intercontinental Airport East

    6115 Will Clayton Parkway, Humble, TX
    The price is $59 per night from Oct 2 to Oct 3
    $59
    per night
    Oct 2 - Oct 3
    7.2/10 Good! (1,983 reviews)
    Hyatt Place Houston / The Woodlands

    Hyatt Place Houston / The Woodlands

    1909 Research Forest Drive, The Woodlands, TX
    The price is $112 per night from Sep 29 to Sep 30
    $112
    per night
    Sep 29 - Sep 30
    8.6/10 Excellent! (1,003 reviews)

Pet Friendly South Central Houston Hotels

    Club Quarters Hotel Downtown, Houston

    Club Quarters Hotel Downtown, Houston

    720 Fannin Street, Houston, TX
    The price is $126 per night from Oct 6 to Oct 7
    $126
    per night
    Oct 6 - Oct 7
    8/10 Very Good! (3,091 reviews)
    Hilton Americas-Houston

    Hilton Americas-Houston

    1600 Lamar Street, Houston, TX
    The price is $212 per night from Oct 6 to Oct 7
    $212
    per night
    Oct 6 - Oct 7
    9/10 Wonderful! (1,001 reviews)
    The Royal Sonesta Houston Galleria

    The Royal Sonesta Houston Galleria

    2222 West Loop South, Houston, TX
    The price is $178 per night from Sep 29 to Sep 30
    $178
    per night
    Sep 29 - Sep 30
    8.2/10 Very Good! (1,000 reviews)
South Central Houston Hotels

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Great selection of hotels in South Central Houston

Whether you're searching for hotels in South Central Houston on business, or hunting for a family getaway, South Central Houston hotel options are only a click away. Find hotels in South Central Houston with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view South Central Houston hotels close you are to the airport and nearby attractions.

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Thanks to photos and virtual tours, you can look before you book your South Central Houston hotel reservation. Check out South Central Houston hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in South Central Houston with unbiased reviews from verified South Central Houston hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

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South Central Houston hotels essential information

Accommodation
1,040 hotels
Lowest Price
$55
Highest Price
$263
Popular hotels
Hotel Zaza Houston Museum District, InterContinental Houston, an IHG Hotel, Hilton Houston Plaza/Medical Center, The Westin Houston Medical Center/Museum District, SureStay Plus Hotel by Best Western Houston Medical Center, Houston Marriott Medical Center/Museum District, DoubleTree by Hilton Houston Medical Center Hotel & Suites, Extended Stay America Suites Houston Med Ctr Braeswood Bl, Sonder The Hampstead

Popular places to visit

Image for Rice University

Rice University

4.5/5(356 reviews)

Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's fascinating museums and acclaimed art scene.

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Rice University
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Houston Zoo

4.5/5(998 reviews)

Why not visit the native and exotic animals at Houston Zoo and see why this is a popular attraction in Houston? Experience the area's fascinating museums and great live music.

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Houston Zoo
Image for University of Houston

University of Houston

4/5(392 reviews)

Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the fascinating museums and acclaimed theater scene in this vibrant area.

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University of Houston

Recent Reviews

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

5/5 Excellent
"Always stay at the Zaza when I'm in Houston. Love the vibe of this hotel "
A verified traveler stayed at Hotel Zaza Houston Museum District
Posted 1 day ago
Hotel Zaza Houston Museum District

Areas Of South Central Houston

Hotels Near