Hotels in South Central Houston
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Tomorrow night
Check prices in South Central Houston for tomorrow night, May 17 - May 18Featured Hotels in South Central Houston

Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Free Cancellation
Reserve now, pay when you stay
1.66 mi from South Central Houston
$223 nightly
The price is $261 total per night
$261 total
May 25 - May 26
Total with taxes and fees
Hotel Zaza Houston Museum District features a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for USD 60 per night, and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with concierge services, dry cleaning/laundry, and luggage storage. Other amenities at this luxury hotel include a sauna, free WiFi in public areas, and conference space.
Pool
Spa

Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Free Cancellation
Reserve now, pay when you stay
2.74 mi from South Central Houston
$85 nightly
The price is $99 total per night
$99 total
May 24 - May 25
Total with taxes and fees
Guests staying at Hilton Houston Plaza/Medical Center enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 20 per day. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, securing valuables, and concierge services. Other amenities at this luxury hotel include meeting rooms, conference space, and coffee/tea in a common area.
Pool
Free WiFi

Sentral Forme Houston
5501 La Branch Street Houston TX
Free Cancellation
Reserve now, pay when you stay
1.34 mi from South Central Houston
$184 nightly
The price is $215 total per night
$215 total
May 17 - May 18
Total with taxes and fees
Built in 2023, the brand new Sentral Forme Houston offers an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 25 per day. Front-desk staff are standing by 24/7 to assist with any requests. Other amenities at this luxury aparthotel include a hot tub, meeting rooms, and express check-in.
Pool
Hot Tub

InterContinental Houston by IHG
6750 Main St Houston TX
Free Cancellation
2.89 mi from South Central Houston
$173 nightly
The price is $203 total per night
$203 total
May 17 - May 18
Total with taxes and fees
Guests of InterContinental Houston by IHG have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Parking is available for USD 40 per day (USD 53 per day for valet parking), and there's also a free area shuttle. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and concierge services. Additional amenities include conference space, a 24-hour business center, and express check-out.
Pool
Pet friendly

The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Free Cancellation
Reserve now, pay when you stay
2.65 mi from South Central Houston
$173 nightly
The price is $201 total per night
$201 total
May 22 - May 23
Total with taxes and fees
At The Westin Houston Medical Center/Museum District, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 54 per night. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Pet friendly

Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
Free Cancellation
Reserve now, pay when you stay
0.95 mi from South Central Houston
$87 nightly
The price is $102 total per night
$102 total
May 17 - May 18
Total with taxes and fees
Downtowner Inns - Houston Downtown features free WiFi in public areas and a vending machine. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations.
Breakfast included
Parking included

Americas Best Value Inn Medical Center Downtown
2419 Riverside Dr Houston TX
Free Cancellation
Reserve now, pay when you stay
1.16 mi from South Central Houston
$84 nightly
The price is $98 total per night
$98 total
May 17 - May 18
Total with taxes and fees
At Americas Best Value Inn Medical Center Downtown, guests have access to free WiFi in public areas, coffee in a common area, and express check-out. Free parking is included with your stay. The front desk is staffed 24/7 to help with tours or tickets, and answer any questions about the accommodations. This motel also has a vending machine.
Parking included
Free WiFi

DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
Free Cancellation
Reserve now, pay when you stay
2.91 mi from South Central Houston
$122 nightly
The price is $143 total per night
$143 total
May 21 - May 22
Total with taxes and fees
At DoubleTree by Hilton Houston Medical Center Hotel & Suites, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, self parking is USD 25.00 per night, and there's also a free area shuttle. The 24-hour front desk has multilingual staff ready to assist with luggage storage and securing valuables. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Pet friendly

Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
Free Cancellation
Reserve now, pay when you stay
2.89 mi from South Central Houston
$73 nightly
The price is $85 total per night
$85 total
May 25 - May 26
Total with taxes and fees
Guests of Extended Stay America Suites Houston Med Ctr Braeswood Bl have access to an outdoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include conference space, coffee/tea in a common area, and laundry facilities.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in South Central Houston
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Central Houston hotels essential information
Accommodation | 1,159 hotels |
|---|---|
Lowest Price | $85 |
Highest Price | $261 |
Popular hotels | Hotel Zaza Houston Museum District, Hilton Houston Plaza/Medical Center, Sentral Forme Houston, InterContinental Houston by IHG, The Westin Houston Medical Center/Museum District, Downtowner Inns - Houston Downtown, Americas Best Value Inn Medical Center Downtown, DoubleTree by Hilton Houston Medical Center Hotel & Suites, Extended Stay America Suites Houston Med Ctr Braeswood Bl |
Popular places to visit

Rice University
Enjoy the collegiate vibe when you visit Rice University, during your travels in Houston. Experience the area's lively festivals and acclaimed theater scene.

Houston Zoo
Why not visit the native and exotic animals who call Houston Zoo home during your trip to Houston? Experience the area's fascinating museums and great live music.

University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the great live music and fascinating museums in this vibrant area.
Recent Reviews

Sentral Forme Houston
5/5 Excellent
"The Property was under renovations but the project was well managed and did not detract from the visitor experience. The property is located a very short walking distance from the Museum district as well as some very nice dining locations. The room had a fully appointed kitchen and washer and dryer - how cool was that. If your planning a museums outting, this is the place to stay!!!! You can literally save yourself a good amount of time and money on parking by simply wallking.
We will definitely be staying here for future visits."
A verified traveler stayed at Sentral Forme Houston
Posted 2 hours ago
More to Explore
- Hotels near George R. Brown Convention Center
- Hotels in Downtown Houston
- Hotels with Free Airport Shuttle in Houston
- Flights to Houston
- Hotels in Houston Museum District
- Hotels near Rice University
- Hotels near Houston Natural Science Museum
- Hotels near NRG Stadium
- Hotels near MD Anderson Cancer Center
- Hotels in Texas Medical Center
- Hotels near Toyota Center
- Cheap Hotels in Houston
- Hotels near Houston Zoo
- Houston vacations
- Hotels near University of Houston
- Hotels near Texas Southern University
- Hotels in Houston
- Car rentals in Houston
- Hotels in Midtown


