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Best Western Plus Sikeston I-55

2.5 star property

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Photo gallery for Best Western Plus Sikeston I-55

Free daily full breakfast
Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cribs/infant beds
Lobby
Indoor pool
Exterior

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Air conditioning
  • Gym

Explore the area

View in a map
120 S Interstate Drive, Sikeston, MO, 63801
  • Place, City of Miner Convention Center
    ‪16 min walk‬
  • Place, Sikeston Depot Museum
    ‪5 min drive‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪31 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪22 min drive‬

Room options

View all photos for Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

A hotel room with a bed, desk, television, microwave, and two lamps.

Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

  • Sleeps 2

View all photos for Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave

  • Sleeps 4

View all photos for Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

A hotel room with a bed, desk, television, microwave, and two lamps.

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

  • Sleeps 2

View all photos for Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

8.6 out of 10
Excellent
(16 reviews)
  • 240 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave

Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave

8.8 out of 10
Excellent
(6 reviews)
  • 240 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave

8.6 out of 10
Excellent
(50 reviews)
  • 240 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)

10.0 out of 10
Exceptional
(2 reviews)
  • 320 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 1 King Bed, Accessible, Refrigerator & Microwave

8.0 out of 10
Very good
(1 review)
  • 240 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Laptop workspace, iron/ironing board, free cribs/infant beds

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

8.0 out of 10
Very good
(22 reviews)
  • 240 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

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Drury Inn & Suites Sikeston, MO

Sikeston
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
9.6 out of 10, Exceptional, 1,002 reviews
$111 nightly
The price is $128
Jul 9 - Jul 10
Total with taxes and fees
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About the neighborhood

Sikeston

Located within a leisurely stroll of City of Miner Convention Center, Best Western Plus Sikeston I-55 is within a 10-minute drive of Sikeston Depot Museum. This 55-room hotel welcomes guests with conveniences like free breakfast, an indoor pool, and free self parking.

What's nearby

  • City of Miner Convention Center - 16 min walk - 0.9 miles
  • Central Park - 5 min drive - 4.6 miles
  • Sikeston Depot Museum - 5 min drive - 4.6 miles
  • Southeast Missouri State University - 30 min drive - 38.3 miles
  • Century Casino & Hotel Cape Girardeau - 31 min drive - 37.8 miles

Getting around

  • Cairo, IL (CIR-Cairo Regional) - 30 min drive

Restaurants

  • ‪Lambert's Cafe - ‬3 min drive
  • ‪Buffalo Wild Wings - ‬6 min drive
  • ‪Imo's Pizza - ‬7 min drive
  • ‪Burger King - ‬5 min drive
  • ‪Starbucks - ‬7 min drive

About this property

Best Western Plus Sikeston I-55

Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Guests can expect WiFi and 42-inch LCD TVs with cable channels. Bathrooms have hair dryers and free toiletries. Other amenities include MP3 docks, microwaves, and coffee makers.
Recreational amenities at the hotel include an indoor pool and a fitness center.

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Drury Inn & Suites Sikeston, MO
Sikeston
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
9.6 out of 10, Exceptional, 1,002 reviews
$111 nightly
The price is $128
Jul 9 - Jul 10
Total with taxes and fees
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Property amenities

Internet

  • Available in all rooms: WiFi (USD 1 per stay)
  • In-room WiFi speed: 25+ Mbps
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free uncovered self parking on site
  • Free RV/bus/truck parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free full breakfast available daily 6:00 AM to 9:00 AM

Things to do

  • Gym
  • Indoor pool
  • Shopping

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • Grocery/convenience store
  • Laundry facilities
  • Water dispenser

Guest services

  • Housekeeping (daily)

Business services

  • 24-hour business center
  • Computer station

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 3 accessible parking spaces
  • Braille/raised signage
  • Elevator (36 inch wide door)
  • Hand-held showerhead
  • Handrails in stairways (34 inches high)
  • Height-adjustable showerhead
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible van parking

More

  • 2 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Free crib
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 42-inch LCD TV with premium cable channels
  • MP3 dock

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning
  • Free local calls
  • Iron/ironing board
  • Laptop workspace

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: anytime
Early check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Late check-out subject to availability
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 25.00 per pet, per night
  • Restrictions apply
  • For more information, guests can reach out to the property at the number on the booking confirmation
  • Service animals exempt from fees

Children and extra beds

  • Rollaway/extra beds are available for USD 10.0 per stay
  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Fee for in-room wireless internet: USD 1 per stay (rates may vary)
  • Pet fee: USD 25.00 per pet, per night
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 10.0 per stay

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western)
  • Check-in: 3 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services. Driving? This property offers free self parking, along with free RV, bus, and truck parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a fire extinguisher.
  • This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western).

Property is also known as

Best Western Plus Hotel Sikeston
Best Western Plus Sikeston
Holiday Inn Express Sikeston Hotel Sikeston
Best Western Plus Sikeston Hotel
Best Western Plus Sikeston Hotel Miner
Best Western Plus Sikeston Miner
Best Plus Sikeston Sikeston
Best Western Plus Sikeston Hotel
Best Western Plus Sikeston Hotel
Hotel Best Western Plus Sikeston Sikeston
Sikeston Best Western Plus Sikeston Hotel
Hotel Best Western Plus Sikeston
Best Western Plus Sikeston Sikeston
Best Western Plus Hotel
Best Western Plus
Best Western Plus Sikeston
Best Western Plus Sikeston Sikeston
Best Western Plus Sikeston Hotel Sikeston

Frequently asked questions

What is there to do near Best Western Plus Sikeston I-55?

This hotel is located in Sikeston, close to Sikeston Depot Museum and Central Park.

How much does it cost to stay at Best Western Plus Sikeston I-55?

As of Jul 4, 2026, prices found for a 1-night stay for 2 adults at Best Western Plus Sikeston I-55 on Jul 26, 2026 start from $97, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available on site at Best Western Plus Sikeston I-55?

Yes, uncovered self parking is offered for free at the hotel. Free RV/bus/truck parking and wheelchair-accessible van parking are also available for guests.

Does Best Western Plus Sikeston I-55 include a casino at the property?

No, Best Western Plus Sikeston I-55 doesn't have a casino.

Is there an indoor pool at Best Western Plus Sikeston I-55?

Yes, this hotel has an indoor pool.

What amenities will couples enjoy at Best Western Plus Sikeston I-55?

Couples staying at this hotel will appreciate amenities like an indoor pool and a free daily breakfast plus some guestrooms include free WiFi.

Does Best Western Plus Sikeston I-55 have a hot tub?

No, there isn't a spa tub at this hotel.

Does Best Western Plus Sikeston I-55 have a restaurant with a breakfast menu?

Best Western Plus Sikeston I-55 offers free full breakfasts each morning though there is no restaurant.

Does Best Western Plus Sikeston I-55 allow pets to stay free of charge?

Although they can't stay for free, pets are welcome at Best Western Plus Sikeston I-55 for a fee of USD 25.00 per pet, per night.

Does Best Western Plus Sikeston I-55 have connecting rooms available?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

What is the closest airport to Best Western Plus Sikeston I-55?

The closest major airport to Best Western Plus Sikeston I-55 is Cairo, IL (CIR-Cairo Regional), which is 28.5 mi away (30 minutes by car). Another top airport is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 26.7 mi away (29-minute drive).

Are there rooms with balconies that I can book at Best Western Plus Sikeston I-55?

No, you won't find guestrooms with balconies at Best Western Plus Sikeston I-55.

Best Western Plus Sikeston I-55 Reviews

Reviews

8.4

Very Good

Rating 10 - Excellent. 463 out of 1000 reviews
Rating 8 - Good. 329 out of 1000 reviews
Rating 6 - Okay. 119 out of 1000 reviews
Rating 4 - Poor. 54 out of 1000 reviews
Rating 2 - Terrible. 35 out of 1000 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.0/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Dianna

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean, breakfast was good, staff was friendly
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
Very nice folks who manage the hotel!!
Stayed 1 night in Feb 2026
Verified

6/10 Okay

Roger

Liked: Staff & service, property conditions & facilities
nice and covenant have stay here a few times, staff always has a smile.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Jim

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It’s an older hotel, but the staff was friendly and helpful. Pool area was nice and breakfast was good.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Bill

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast selection was fresh but not overwhelming in quality.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Lydia

Liked: Cleanliness
Room was clean, the bathroom had a good vent and nice lighting which we've had a problem with with other hotels. Very satisfied with our stay and breakfast was gold.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Charles

Liked: Cleanliness
Great stay, everything was clean and comfortable.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Mark

Liked: Cleanliness, amenities, property conditions & facilities
Nice people, quiet stay.
Stayed 4 nights in Nov 2025
Verified

8/10 Good

Jackie

Liked: Cleanliness, staff & service, amenities
Very nice staff. Quiet hotel. Would stay again.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

scott

Liked: Cleanliness, amenities, property conditions & facilities
Everything about our stay (just the one night) was great.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, amenities
Clean facility service was excellent.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Dawn

Liked: Cleanliness, staff & service, amenities
Staff was great.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

joseph

Liked: Cleanliness, amenities, property conditions & facilities
Easy parking , quiet and comfortable bed , we’ll stop again on our way back
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Kendra

Liked: Cleanliness, amenities, property conditions & facilities
Thestaff at the front counter was awesome.
Stayed 2 nights in Feb 2026
Verified

8/10 Good

Pat

Liked: Cleanliness, staff & service, amenities
This is an old hotel that could use updating. The staff was great
Stayed 1 night in Feb 2026
Verified

8/10 Good

Thomas

Liked: Cleanliness, amenities, property conditions & facilities
Staff was courteous and room was clean and the fron
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Phyllis

Liked: Cleanliness, amenities, property conditions & facilities
Great breakfast. Clean room Quiet
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

carmen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our stay and the breakfast was good!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is such a nice clean place to stay. Breakfast was really good and the staff so nice and helpful.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Duwaine

Liked: Amenities
Very convenient and great breakfast
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Carla

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice location. Great staff.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Dawn

Liked: Cleanliness, staff & service, property conditions & facilities
Friendly staff nice rooms, Breakfast is awesome
Stayed 1 night in Apr 2025
Verified

8/10 Good

Les

Liked: Cleanliness, amenities, property conditions & facilities
Everything was very good from entering to exiting.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Jordan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice and affordable option! Quiet place with clean facility throughout. Great people and good service.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Shannon

Liked: Cleanliness, staff & service, amenities
Great place to stay to stop over for the night. Very clean. Great value.
Stayed 1 night in Dec 2025