Hotels in Mesilla

Name: Best Western Mission Inn
Price range: $89 total

Search over 380 hotels from $59

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Dec 25 - Dec 26

Tonight

Dec 26 - Dec 27

Tomorrow night

Top Rated Mesilla Hotels

Josefina's King Suite in Historic Old Mesilla Plaza.

0.46 mi from city center

This apartment is a smoke-free apartment building.

Air conditioning

Casita Azul, Mesilla Plaza Only Steps Away

0.37 mi from city center

At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.

Kitchen

Washer

Free Cancellation

Reserve now, pay when you stay

4.53 mi from city center

$148 nightly

$171 total

Jan 1 - Jan 2, 2026

Total with taxes and fees

Hotel Encanto de Las Cruces features a nightclub, an outdoor pool, and a 24-hour gym. Multilingual staff at the 24-hour front desk can assist with luggage storage, securing valuables, and concierge services. Additional amenities include a hot tub, meeting rooms, and conference space.

Pool

Hot Tub

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Free Cancellation

Reserve now, pay when you stay

1.62 mi from city center

$57 nightly

$67 total

Dec 30 - Dec 31

Total with taxes and fees

Guests of La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain enjoy features like an outdoor pool, free WiFi in public areas, and laundry facilities. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready.

Pool

Breakfast included

Free Cancellation

Reserve now, pay when you stay

1.73 mi from city center

$50 nightly

$59 total

Jan 19 - Jan 20, 2026

Total with taxes and fees

At Days Inn by Wyndham Las Cruces, guests have access to an outdoor pool, free WiFi in public areas, and a 24-hour business center. If you decide to drive, there's free parking. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.

Pool

Breakfast included

Free Cancellation

Reserve now, pay when you stay

3.92 mi from city center

$92 nightly

$107 total

Jan 11 - Jan 12, 2026

Total with taxes and fees

At Hilton Garden Inn Las Cruces, guests have access to a 24-hour gym, free WiFi in public areas, and a hot tub. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Hot Tub

Pet friendly

Free Cancellation

Reserve now, pay when you stay

1.56 mi from city center

$94 nightly

$109 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

Guests staying at Drury Inn & Suites Las Cruces enjoy an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.

Pool

Hot Tub

Free Cancellation

Reserve now, pay when you stay

3.71 mi from city center

$78 nightly

$91 total

Jan 11 - Jan 12, 2026

Total with taxes and fees

At Comfort Suites University Las Cruces, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. Front-desk staff can answer questions 24/7, and assist with securing valuables, concierge services, and dry cleaning/laundry. Other amenities at this golf hotel include a 24-hour business center, coffee/tea in a common area, and express check-out.

Pool

Breakfast included

Free Cancellation

Reserve now, pay when you stay

4.57 mi from city center

$113 nightly

$131 total

Dec 28 - Dec 29

Total with taxes and fees

Guests staying at Comfort Suites Las Cruces I-25 North enjoy an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.

Pool

Hot Tub

Free Cancellation

Reserve now, pay when you stay

4.38 mi from city center

$89 nightly

$104 total

Jan 1 - Jan 2, 2026

Total with taxes and fees

Guests of Hampton Inn & Suites Las Cruces I-25 have access to an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and luggage storage. Additional amenities include a hot tub, meeting rooms, and a 24-hour business center.

Pool

Hot Tub

Springhill Suites By Marriott Las Cruces

Free Cancellation

Reserve now, pay when you stay

1.65 mi from city center

$93 nightly

$108 total

Dec 29 - Dec 30

Total with taxes and fees

At Springhill Suites By Marriott Las Cruces, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, a conference center, and coffee/tea in a common area.

Pool

Hot Tub

Free Cancellation

Reserve now, pay when you stay

2.03 mi from city center

$77 nightly

$89 total

Dec 28 - Dec 29

Total with taxes and fees

Best Western Mission Inn features an outdoor pool, free WiFi in public areas, and a business center. There's free parking if you drive. The 24-hour front desk has multilingual staff ready to assist with securing valuables and luggage storage. Additional amenities include coffee/tea in a common area, a meeting room, and express check-in.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where is a good place to stay in Mesilla?

What are the best hotels in downtown Mesilla?

Here are some of our travelers' favorite hotels in central Mesilla:

Hotel Encanto de Las Cruces is hotel has 3 bars, a nightclub, and a 24-hour fitness center.
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain is hotel has free breakfast, free WiFi, and free parking.
Days Inn by Wyndham Las Cruces is hotel has free breakfast, free WiFi, and free parking.

Close to central Mesilla, you'll find interesting places to visit like Mesillia Plaza.

What are the best hotels to stay near Old Mesilla Village?

Invest in experiences, not things. While you're in Mesilla, that should include Old Mesilla Village. Spend an afternoon at this renowned historic village, 1 mile from the city center, before stopping by worthwhile nearby sights like Rio Grande Vineyards and Winery. Make life easier by sleeping somewhere close by, like Villa Esperanza 2-125. It's 0.1 miles from Old Mesilla Village. Also look up the offers at Casita Azul - Just Steps Away From the Plaza, 0.2 miles away, and Adorable Adobe Casita in Old Mesilla - Near Nmsu, 0.2 miles away. If you're in the mood to live it up a little, Fountain Theatre is a popular place to go when the sun sets.

Mesilla hotels essential information

Accommodation	380 hotels
Lowest Price	$59
Highest Price	$171
Popular hotels	Josefina's King Suite in Historic Old Mesilla Plaza., Casita Azul, Mesilla Plaza Only Steps Away, Hotel Encanto de Las Cruces, La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain, Days Inn by Wyndham Las Cruces, Hilton Garden Inn Las Cruces, Drury Inn & Suites Las Cruces, Comfort Suites University Las Cruces, Comfort Suites Las Cruces I-25 North, Hampton Inn & Suites Las Cruces I-25, Springhill Suites By Marriott Las Cruces, Best Western Mission Inn