Florida Keys Vacation Homes

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Featured Vacation Homes in Florida Keys

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florida Keys

    Cheeca Lodge & Spa

    Cheeca Lodge & Spa

    81801 Overseas Highway, Mile Marker 82 Islamorada FL
    $236 nightly
    The price is $266 total per night from Nov 29 to Nov 30
    $266 total
    Nov 29 - Nov 30
    Total with taxes and fees
    9.2/10 Wonderful! (1,502 reviews)
    Isla Bella Beach Resort & Spa

    Isla Bella Beach Resort & Spa

    1 Knights Key Boulevard Marathon FL
    $293 nightly
    The price is $330 total per night from Dec 2 to Dec 3
    $330 total
    Dec 2 - Dec 3
    Total with taxes and fees
    9.2/10 Wonderful! (1,305 reviews)
    Reefhouse Resort & Marina

    Reefhouse Resort & Marina

    103800 Overseas Hwy Key Largo FL
    $259 nightly
    The price is $286 total per night from Nov 29 to Nov 30
    $286 total
    Nov 29 - Nov 30
    Total with taxes and fees
    9.2/10 Wonderful! (1,559 reviews)

Florida Keys Vacation Homes

Book vacation homes in Florida Keys
Next time you take a group getaway top Florida Keys, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Florida Keys vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Florida Keys vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Florida Keys; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Florida Keys rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Florida Keys is sure to be a winner.

Florida Keys Vacation Homes essential information

Accommodation
1043 Vacation Homes
Lowest Price
$228
Highest Price
$856
Popular accommodation
Sugarloaf Key RV Resort & Cottages, Bluegreen Vacations Hammocks at Marathon, Ascend Collection Resort, Charming 3-bedroom house featuring a heated private pool., VOTED BEST KEY LARGO VACATION RENTAL, Views ~ Pool~Private Hot Tub~FREE Boat Slip~Heaven!!!, Private Secluded Ocean View & Pool Near Key West, Piece of Paradise located at Hawks Cay in Duck Key, Tipsy Turtle: Luxurious Waterfront Villa on Duck Key with Stunning Views and Modern Upgrades!, FALL SEASON 55% OFF RENTAL RATE