Florida Keys Vacation Homes

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Featured Vacation Homes in Florida Keys

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florida Keys

    Cheeca Lodge & Spa

    Cheeca Lodge & Spa

    81801 Overseas Highway, Mile Marker 82 Islamorada FL
    $214 nightly
    The price is $241 total per night from Aug 12 to Aug 13
    $241 total
    Aug 12 - Aug 13
    Total with taxes and fees
    9.2/10 Wonderful! (1,385 reviews)
    Isla Bella Beach Resort & Spa

    Isla Bella Beach Resort & Spa

    1 Knights Key Boulevard Marathon FL
    $303 nightly
    The price is $341 total per night from Aug 12 to Aug 13
    $341 total
    Aug 12 - Aug 13
    Total with taxes and fees
    9.2/10 Wonderful! (1,235 reviews)
    Hawks Cay Resort

    Hawks Cay Resort

    61 Hawks Cay Blvd Marathon FL
    $264 nightly
    The price is $295 total per night from Aug 17 to Aug 18
    $295 total
    Aug 17 - Aug 18
    Total with taxes and fees

Florida Keys Vacation Homes

Book vacation homes in Florida Keys
Next time you take a group getaway top Florida Keys, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Florida Keys vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Florida Keys vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Florida Keys; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Florida Keys rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Florida Keys is sure to be a winner.

Florida Keys Vacation Homes essential information

Accommodation
1048 Vacation Homes
Lowest Price
$241
Highest Price
$730
Popular accommodation
Sugarloaf Key RV Resort & Cottages, BRAND NEW! KEYS BEACH RETREAT! CAPTIVATING WATERVIEW VILLA! WIFI! FREE GOLF CART, 7 Bedroom with Dockage, Pool, Firepit, Paddle Boards & Kayaks , Private Beachfront Paradise, Coral Lagoon #13: Heated Pool, Views, easy Gulf & Atlantic Access via Vaca Cut, Paradise Oceanside Estate- 6 Bedrooms & 9 BR + Office + Theater Room – SLEEPS 14, Waterfront - Private Lagoon - in Park on the Ocean side -beach, pool, Private Oceanfront home with 2024 Swim spa , paddle-boards,kayaks, & bikes., Sunrise Escape - Ocean Front Villa - Sleeps 10