Florida Keys Vacation Homes

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Featured Vacation Homes in Florida Keys

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florida Keys

    Reefhouse Resort & Marina

    Reefhouse Resort & Marina

    103800 Overseas Hwy Key Largo FL
    $299 nightly
    The price is $331 total per night from May 19 to May 20
    $331 total
    May 19 - May 20
    Total with taxes and fees
    9.4/10 Exceptional! (1,437 reviews)
    Chesapeake Beach Resort

    Chesapeake Beach Resort

    83409 Overseas Hwy Islamorada FL
    $226 nightly
    The price is $254 total per night from Jun 9 to Jun 10
    $254 total
    Jun 9 - Jun 10
    Total with taxes and fees
    9.2/10 Wonderful! (1,729 reviews)
    Marina Del Mar Resort and Marina

    Marina Del Mar Resort and Marina

    527 Caribbean Drive Key Largo FL
    $149 nightly
    The price is $167 total per night from May 27 to May 28
    $167 total
    May 27 - May 28
    Total with taxes and fees
    8.6/10 Excellent! (1,794 reviews)

Florida Keys Vacation Homes

Book vacation homes in Florida Keys
Next time you take a group getaway top Florida Keys, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Florida Keys vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Florida Keys vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Florida Keys; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Florida Keys rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Florida Keys is sure to be a winner.

Florida Keys Vacation Homes essential information

Accommodation
983 Vacation Homes
Lowest Price
$167
Highest Price
$841
Popular accommodation
Sugarloaf Key RV Resort & Cottages, The Hammocks at Marathon, Dog-Friendly, Water Front Home with Tiki Hut and 40 Ft Dock and Launch, BRAND NEW! KEYS BEACH RETREAT! CAPTIVATING WATERVIEW VILLA! WIFI! FREE GOLF CART, Old Florida Style, wrap around porch, boat basin for dockage, open water, Villa hermosa, La Fuentes, Oceanfront, Pool, Tiki, Amazing Views, Near Vaca, Great Dockage, Kayaks, Bikes, Coral Lagoon Single Family Home includes 40' Boat Slip directly behind home. New