Florida Keys Vacation Homes

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Featured Vacation Homes in Florida Keys

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Florida Keys

    Cheeca Lodge & Spa

    Cheeca Lodge & Spa

    81801 Overseas Highway, Mile Marker 82 Islamorada FL
    $226 nightly
    The price is $254 total per night from Jul 19 to Jul 20
    $254 total
    Jul 19 - Jul 20
    Total with taxes and fees
    9.2/10 Wonderful! (1,348 reviews)
    Hawks Cay Resort

    Hawks Cay Resort

    61 Hawks Cay Blvd Marathon FL
    $291 nightly
    The price is $326 total per night from Jul 20 to Jul 21
    $326 total
    Jul 20 - Jul 21
    Total with taxes and fees
    8.2/10 Very Good! (1,016 reviews)
    Isla Bella Beach Resort & Spa

    Isla Bella Beach Resort & Spa

    1 Knights Key Boulevard Marathon FL
    $269 nightly
    The price is $302 total per night from Aug 13 to Aug 14
    $302 total
    Aug 13 - Aug 14
    Total with taxes and fees
    9.2/10 Wonderful! (1,202 reviews)

Florida Keys Vacation Homes

Book vacation homes in Florida Keys
Next time you take a group getaway top Florida Keys, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Florida Keys vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Florida Keys vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Florida Keys; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Florida Keys rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Florida Keys is sure to be a winner.

Florida Keys Vacation Homes essential information

Accommodation
1074 Vacation Homes
Lowest Price
$254
Highest Price
$326
Popular accommodation
Sugarloaf Key RV Resort & Cottages, New Listing Luxury Open Ocean Front Views, Dockage Pool/spa Tiki RELAX TIME, Waterfront - Private Lagoon - in Park on the Ocean side -beach, pool, Mariners Club Unit 904, VRNR Luxury Collection, Brand New Completely Remodeled, Waterfront 2BR w/ Dock, Hot Tub & Easy Ocean Access – Boaters Welcome!, Turquoise Lagoon LLC, wide open turquoise views of the lagoon, Bluegreen Vacations Hammocks at Marathon, Ascend Collection Resort, Oceanside in the FL Keys Free Kayaks Bikes Pool & Hot Tub Tennis & Pickle ball, KCB-access Private Cabana Club, Dock on Canal, PET Friendly, Pickle ball courts