$101 Cheap flights to Santiago Metropolitan Region
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Top places to visit in Santiago Metropolitan Region
Cheap flights to Santiago Metropolitan Region from $101 One Way, $169 Round Trip
$169 return flights and $101 one-way flights to Santiago Metropolitan Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GRU | Santiago | July 18 to July 25 | $294 |
| EZE | Santiago | July 17 to July 19 | $569 |
| MIA | Santiago | July 19 to July 28 | $930 |
| YYZ | Santiago | July 18 to July 21 | $931 |
| JFK | Santiago | July 17 to July 24 | $962 |
| LAX | Santiago | July 18 to July 22 | $1,068 |
| LGA | Santiago | July 19 to July 24 | $1,236 |
| MAD | Santiago | July 17 to July 25 | $1,350 |
Find The Perfect Hotel For After Your Flight
Score Epic Santiago Metropolitan Region Accommodation Deals
Altura Suites
City Express by Marriott Santiago Aeropuerto Chile
"Bien"
Reviewed on Jul 13, 2026
Hotel Paris Londres
"I was turned away after came in from the airport at 2am. I was told I need to come back at 11am. I was charged the entire stay regardless. I wouldn't recommend this hotel to anyone"
Reviewed on Mar 16, 2018
RQ Santiago
Our Top Santiago Metropolitan Region Apartment Hotels
Altura Suites
myLUXAPART Arturo Prat
"Nice apartment..receorion didnt speak English but we managed to get by ..at the time in Santiago there was political protests happening and the area was a little unsafe but apartment perfect and swimming pool lovely"
Reviewed on Nov 26, 2019
Plaza Suites
"This isn't really a hotel for tourists especially if you speak no Spanish. It is geared to intermediate term rentals to people in town temporarily, say for work assignment. There are limited hotel services. Sheets and towels are changed every three days. However, it is in a very good location, near ..."
Reviewed on Apr 7, 2018
Bellavista Apartments
"Property was not clean , no WiFi , hard to find location. Pictures on Expedia website and other booking sites will mislead. Location Kinda party place , not recommend for family."
Reviewed on Dec 25, 2019
Score Epic Santiago Metropolitan Region Accommodation Deals
Holiday Inn Santiago - Airport Terminal by IHG
"The pool hours were ridiculous. Opening at 10 am when the whole point for those with early, long flights is to have a nice relaxing swim beforehand. The pool is always unattended and was ready to use at 7 am so it is hard to see why it could not be open then or even earlier. Otherwise, the hotel ..."
Reviewed on Jul 14, 2026
Mandarin Oriental, Santiago
"The staff Was Very friendly the hotel was well. Location rooms were big and comfortable. The front desk and the restaurant. Staff was amazing. The food really very excellent."
Reviewed on Jun 30, 2026
Nest Paris-Londres
"Durong our vacation we stayed twice at Nest Paris Londres. The rooms were big, beautiful, new, well equipped and clean. Cristobal in the reception was friendly, approachable and very resourceful."
Reviewed on Jul 10, 2026
Hotel Plaza San Francisco
"BIG Hotel, that used to be a Parking Garage. Average amenities & dated furniture everywhere."
Reviewed on Jun 23, 2026
Family Friendly Hotels in Santiago Metropolitan Region
Time Select - Elegant Apartments
"A localização do hotel é maravilhosa, uma das melhores em Santiago, soma-se a isso uma estrutura maravilhosa do hotel, a suíte 11A é incr ível, fica dica e recomendação! O time do hotel é super solícito! Nota 10 em tudo!"
Reviewed on Jun 11, 2026
Wyndham Santiago Pettra
Le Méridien Santiago
Hotel Boutique Castillo Rojo
"The hotel is a great place to stay in the city and its soo cool, what I appreciate the most is how hard the hotel staff work to make you feel comfortable"
Reviewed on Jul 14, 2026
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Santiago Metropolitan Region
End your search for discount fares on flights to Santiago Metropolitan Region. Orbitz has all the best prices on Santiago Metropolitan Region flights. With Orbitz, you can expect:
Cheap Deals on Flights to Santiago Metropolitan Region
We offer big discounts and last-minute savings on Santiago Metropolitan Region flights. We make it easy for you to research, plan, and book your flight to Santiago Metropolitan Region — all while offering great low fares. With guaranteed low prices and cutting-edge mobile tools, the perfect trip begins on Orbitz.
Travel Convenience on the Go
Get alerts, updates, or book your Santiago Metropolitan Region flight or other flights wherever you are. Download our free apps for iPhone, Android, and iPad or visit our mobile site at m.orbitz.com to conveniently review or change your air travel plans. We can also send free alerts about your Santiago Metropolitan Region flight to your email or mobile phone, so you get advance warning about potential disruptions and flight delays. Need to book a hotel with your Santiago Metropolitan Region flight? Access exclusive, mobile-only deals via our mobile site and free apps – even on the same day.
Great Customer Care
We want to make your travel booking experience smooth and easy, from planning and researching Santiago Metropolitan Region flights to the actual booking. If you want to cancel your flight to Santiago Metropolitan Region, many tickets can be conveniently cancelled online. Contact our Customer Service to make changes to your air ticket.
Miles or Points Toward Frequent Flyer Programs
Much like booking with an airline directly, you can earn frequent flyer miles or points on qualified flights to Santiago Metropolitan Region with Orbitz. When completing your booking, just fill in your frequent flyer number for the airline you are flying with or for one of its available partner airlines.
Frequently asked questions
More to Explore
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.