Compare Hotels in Lee County

Search over 242 hotels from $58

Start date: Check-in selected.
To Date
End date: Check-out

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Oct 18 - Oct 19
Tonight
Check prices in Lee County for tonight, Oct 18 - Oct 19
Oct 19 - Oct 20
Tomorrow night
Check prices in Lee County for tomorrow night, Oct 19 - Oct 20

Top Rated Lee County Hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $105 total per night
$105 total
Oct 26 - Oct 27
Total with taxes and fees
Park Inn by Radisson Florence, SC features a 24-hour gym, free WiFi in public areas, and a business center. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a computer station, and an arcade/game room.
Breakfast included
Pet friendly
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $120 total per night
$120 total
Nov 2 - Nov 3
Total with taxes and fees
At Comfort Inn & Suites, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $76 total per night
$76 total
Oct 22 - Oct 23
Total with taxes and fees
Howard Johnson by Wyndham Florence features free WiFi in public areas, a business center, and coffee in a common area. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a computer station, a garden, and a vending machine.
Breakfast included
Parking included
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $95 total per night
$95 total
Nov 16 - Nov 17
Total with taxes and fees
Guests of Quality Inn & Suites Florence Civic Center enjoy a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$88 nightly
The price is $99 total per night
$99 total
Oct 21 - Oct 22
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Florence enjoy a gym, free WiFi in public areas, and meeting rooms. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $112 total per night
$112 total
Nov 17 - Nov 18
Total with taxes and fees
Guests staying at Hyatt Place Florence Downtown enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 5.40 per night. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

2.5 out of 5
2715 Broad Street, Sumter, SC
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $133 total per night
$133 total
Oct 26 - Oct 27
Total with taxes and fees
Built in 2025, the brand new Woodspring Suites Sumter Near Shaw Afb offers free WiFi in public areas and laundry facilities. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Pet friendly
Parking included
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$52 nightly
The price is $58 total per night
$58 total
Oct 21 - Oct 22
Total with taxes and fees
Guests of Microtel Inn & Suites by Wyndham Florence enjoy access to free WiFi in public areas, a 24-hour business center, and coffee in a common area. There's free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include express check-out, free newspapers, and a vending machine.
Breakfast included
Pet friendly
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 out of 5
2140 West Lucas Street, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $108 total per night
$108 total
Nov 2 - Nov 3
Total with taxes and fees
Guests of Tru by Hilton Florence I-95 have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and an arcade/game room.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Lee County
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lee County Hotels

Orbitz makes it easy to find the best Lee County hotel deals for your trip. With an outstanding selection, easy-to-use search tools and descriptive hotel profiles, you'll find Lee County hotel deals in a wink..

Great selection of hotels in Lee County

Whether you're searching for hotels in Lee County on business, or hunting for a family getaway, Lee County hotel options are only a click away. Find hotels in Lee County with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Lee County hotels close you are to the airport and nearby attractions.

Lee County hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Lee County hotel reservation. Check out Lee County hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Lee County with unbiased reviews from verified Lee County hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

Grab Lee County hotel deals and special offers

Orbitz works around the clock to find exclusive offers and Lee County hotel deals, just for you. Sign up for deals by e-mail where you'll get first crack at money-saving extras like promo codes, resort credits, free nights and more. You can also "Like" Orbitz on Facebook and follow us on Twitter to receive up-to-the-minute news on hotel discounts, giveaways and more.

24/7 support with Lee County hotel reservations

When it comes to finding hotels in Lee County, an Orbitz specialist can help you find the property right for you. Chat live or call 1-800-454-3743 any time for help booking your hotels in Lee County. Our team of experts can help you pinpoint Lee County hotels options suited to your tastes and budget.

Forget Orbitz change or cancel fees on Lee County hotels

On Orbitz, Lee County hotel deals mean flexibility. If you need to change your Lee County hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Lee County all in one place.

 

Lee County hotels essential information

Accommodation
242 hotels
Lowest Price
$58
Highest Price
$133
Popular hotels
Park Inn by Radisson Florence, SC, Comfort Inn & Suites, Howard Johnson by Wyndham Florence, Quality Inn & Suites Florence Civic Center, La Quinta Inn & Suites by Wyndham Florence, Hyatt Place Florence Downtown, Woodspring Suites Sumter Near Shaw Afb, Microtel Inn & Suites by Wyndham Florence, Tru by Hilton Florence I-95

Recent Reviews

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

5/5 Excellent
"Wish we had more towels, otherwise pretty comfy"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Florence
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Florence

More to Explore