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Dec 16 - Dec 17
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Check prices in Lee County for tonight, Dec 16 - Dec 17
Dec 17 - Dec 18
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Check prices in Lee County for tomorrow night, Dec 17 - Dec 18

Top Rated Lee County Hotels

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $70 total per night
$70 total
Dec 17 - Dec 18
Total with taxes and fees
Howard Johnson by Wyndham Florence features free WiFi in public areas, a business center, and coffee in a common area. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a computer station, a vending machine, and a garden.
Breakfast included
Parking included
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Free Cancellation
$85 nightly
The price is $95 total per night
$95 total
Dec 23 - Dec 24
Total with taxes and fees
Park Inn by Radisson Florence, SC features a 24-hour gym, free WiFi in public areas, and a business center. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a computer station, and an arcade/game room.
Breakfast included
Pet friendly
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $109 total per night
$109 total
Dec 30 - Dec 31
Total with taxes and fees
At Comfort Inn & Suites Florence Center Area, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $112 total per night
$112 total
Dec 22 - Dec 23
Total with taxes and fees
Guests staying at Hyatt Place Florence Downtown enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 5.40 per night. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $111 total per night
$111 total
Dec 23 - Dec 24
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Florence enjoy a gym, free WiFi in public areas, and meeting rooms. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $116 total per night
$116 total
Dec 23 - Dec 24
Total with taxes and fees
At Home2 Suites by Hilton Florence, SC, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and tours or tickets. Additional amenities include a business center, an arcade/game room, and laundry facilities.
Pool
Breakfast included
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 out of 5
2140 West Lucas Street Florence SC
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $106 total per night
$106 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Tru by Hilton Florence I-95 have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and an arcade/game room.
Pool
Breakfast included
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 out of 5
1735 Stokes Road Florence SC
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $121 total per night
$121 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
At Hampton Inn & Suites Florence-North-I-95, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub
Residence Inn Marriott Florence

Residence Inn Marriott Florence

3 out of 5
2660 Hospitality Blvd Florence SC
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $107 total per night
$107 total
Dec 25 - Dec 26
Total with taxes and fees
At Residence Inn Marriott Florence, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 5 per day. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lee County Hotels

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Whether you're searching for hotels in Lee County on business, or hunting for a family getaway, Lee County hotel options are only a click away. Find hotels in Lee County with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Lee County hotels close you are to the airport and nearby attractions.

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Lee County hotels essential information

Accommodation
250 hotels
Lowest Price
$70
Highest Price
$121
Popular hotels
Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Comfort Inn & Suites Florence Center Area, Hyatt Place Florence Downtown, La Quinta Inn & Suites by Wyndham Florence, Home2 Suites by Hilton Florence, SC, Tru by Hilton Florence I-95, Hampton Inn & Suites Florence-North-I-95, Residence Inn Marriott Florence

Recent Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

5/5 Excellent
"Plenty of space, but it also had a cozy/comfortable feel. Staff was super friendly and there was a good variety of items available for the free breakfast. Everything was clean, the bed was very comfortable.. Just 5-10 minutes from 95, and plenry of food and shopping options nearby."
A verified traveler stayed at Comfort Inn & Suites Florence Center Area
Posted 11 hours ago
Comfort Inn & Suites Florence Center Area

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