Central San Diego Vacation Homes

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Featured Vacation Homes in Central San Diego

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Central San Diego

    San Diego Marriott La Jolla

    San Diego Marriott La Jolla

    4240 La Jolla Village Dr, La Jolla, CA
    The price is $183 per night from May 9 to May 10
    $183
    includes taxes & fees
    $159 per night
    May 9 - May 10
    8.4/10 Very Good! (1,753 reviews)
    Days Inn by Wyndham San Diego Hotel Circle

    Days Inn by Wyndham San Diego Hotel Circle

    543 Hotel Circle S, San Diego, CA
    The price is $123 per night from May 7 to May 8
    $123
    includes taxes & fees
    $107 per night
    May 7 - May 8
    7.6/10 Good! (2,167 reviews)
    Kings Inn San Diego

    Kings Inn San Diego

    1333 Hotel Cir S, San Diego, CA
    The price is $116 per night from May 6 to May 7
    $116
    includes taxes & fees
    $102 per night
    May 6 - May 7
    8.6/10 Excellent! (3,223 reviews)

Central San Diego Vacation Homes

Book vacation homes in Central San Diego
Next time you take a group getaway top Central San Diego, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Central San Diego vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Central San Diego vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Central San Diego; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Central San Diego rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Central San Diego is sure to be a winner.

Central San Diego Vacation Homes essential information

Accommodation
657 Vacation Homes
Lowest Price
$116
Highest Price
$354
Popular accommodation
2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay, Beautiful Normal Heights Living, Best Location in San Diego. 3 Story Spanish Style Home in Heart of North Park, Adorable Spanish style casita in fantastic area of Historic North Park, Serene Sanctuary: Pool, Hot Tub & Game Room, Craftsman Bungalow- University Heights 2BR Home, Fox Canyon Hideaway-San Diego, Great Views Studio apartment near Little Italy, Family-friendly 3bd / 2bh with outdoor and dining in SD's best location