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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Free breakfast
Exterior
Indoor pool, open 8 AM to 11 PM, sun loungers
Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning

Explore the area

View in a map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Riverfront Bridge Park
    ‪6 min drive‬
  • Place, Southeast Missouri State University
    ‪7 min drive‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪9 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(35 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(62 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(15 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room, 1 Queen Bed

9.4 out of 10
Exceptional
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

About the neighborhood

Cape Girardeau

Located within a leisurely stroll of Saint Francis Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is within a few miles (5 km) of Saint Francis Healthcare System. This hotel has 102 rooms and welcomes guests with conveniences like free breakfast, a full-service spa, and an indoor pool.

What's nearby

  • Cape Splash Family Aquatic Center - 4 min drive - 2.9 miles
  • Riverfront Bridge Park - 6 min drive - 5.0 miles
  • Southeast Missouri State University - 7 min drive - 5.0 miles
  • Century Casino & Hotel Cape Girardeau - 9 min drive - 6.5 miles
  • Giant City State Park - 55 min drive - 49.1 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Panera Bread - ‬2 min walk
  • ‪White Castle - ‬10 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
52-inch flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries, and pillowtop beds with premium bedding and pillow menus ensure a restful night. Other amenities include sitting areas, microwaves, and coffee makers.
Recreational amenities at the hotel include an indoor pool and a fitness center.
Guests can indulge in a pampering treatment at the hotel's full-service spa.

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The price is $113
May 25 - May 26
Total with taxes and fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business center
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • This property doesn't allow pets

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
  • Check-in: 3:00 PM—-anytime
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a fire extinguisher and a smoke detector.
  • Cashless payment methods are available for all transactions.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 11 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No cribs or infant beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG provides free cancellation on some room rates. For more details, review the cancellation policy on our site.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of May 19, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on May 24, 2026 start from $124, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to see close to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel is located in Cape Girardeau, close to Cape Splash Family Aquatic Center, Riverfront Bridge Park, and Century Casino & Hotel Cape Girardeau. You'll also find Mississippi River and Shawnee National Forest within a short drive.

Is parking available on site at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, self parking is offered for free at the hotel. Wheelchair-accessible parking is also available for guests.

Is there a spa available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

There is a full-service spa at this available for guests to enjoy at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG include a casino at the property?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 11 PM.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG good for couples?

Couples staying at this hotel will appreciate amenities like a pillow menu and free wired internet as well as an indoor pool.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a hot tub?

No, this hotel doesn't have a spa tub.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a restaurant that serves breakfast?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast though there is no restaurant.

Will Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have connecting rooms available?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

How close is the airport from Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

The closest major airport to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 6.1 mi away (10 minutes by car). Another top airport is Cairo, IL (CIR-Cairo Regional), which is around 25.5 mi away.

Are there rooms with balconies that I can book at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there aren't any guestrooms at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG that offer a balcony.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 778 out of 1001 reviews
Rating 8 - Good. 149 out of 1001 reviews
Rating 6 - Okay. 40 out of 1001 reviews
Rating 4 - Poor. 15 out of 1001 reviews
Rating 2 - Terrible. 19 out of 1001 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Nancy

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Very quiet even though the hotel was full. Breakfast was wonderful.
Stayed 1 night in Feb 2026

10/10 Excellent

Grace

Stayed 1 night in Feb 2026

2/10 Terrible

Dean

Stayed 1 night in Feb 2026

8/10 Good

Richard, Maple Grove

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Would have been a 5 rating except for the noisy heating system.
Stayed 1 night in Jan 2026

10/10 Excellent

Rick

Stayed 1 night in Jan 2026

8/10 Good

Mary

Liked: Cleanliness, staff & service, amenities
Clean, courteous staff
Stayed 1 night in Jan 2026

10/10 Excellent

Nicholas F, Spring City

Stayed 1 night in Jan 2026

8/10 Good

Mary

Stayed 1 night in Jan 2026

10/10 Excellent

Deborah

Business traveler
Liked: Cleanliness, staff & service, amenities
Room was spacious and clean. Staff was nice and helpful. Good breakfast.
Stayed 1 night in Jan 2026

8/10 Good

Lorna

Traveled with family
Liked: Cleanliness, staff & service, amenities
Clean rooms. Helpful staff. My only complaint would be about the walls being too thin. We were awoken every morning by noise from neighbors and people walking on floor above us.
Stayed 3 nights in Jan 2026

10/10 Excellent

Andrew

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice room. There was a little noise from other rooms or perhaps from the hallways. The breakfast was very good.
Stayed 1 night in Jan 2026

10/10 Excellent

Bruce, Urbandale

Stayed 1 night in Jan 2026

6/10 Okay

Sydni

Traveled with family
Liked: Cleanliness, staff & service, amenities
The staff were great, but the people in the building were outrageously loud. There were slamming doors and running on floors above me all the way until midnight. It was annoying and really put a bad impression on my stay. I wasn’t satisfied.
Stayed 1 night in Jan 2026

10/10 Excellent

Nick, Farmington

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean rooms
Stayed 1 night in Jan 2026

10/10 Excellent

Andrea

Stayed 1 night in Jan 2026

10/10 Excellent

Brooke

Stayed 1 night in Jan 2026

10/10 Excellent

Janelle, Spanaway

lovely hotel
Stayed 2 nights in Dec 2025

10/10 Excellent

Mary

Stayed 1 night in Dec 2025

10/10 Excellent

Teresa

Stayed 1 night in Dec 2025

10/10 Excellent

Dawn

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Everyone kind & place very clean.
Stayed 1 night in Jan 2026

10/10 Excellent

Rex

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026

8/10 Good

Shardae

Liked: Cleanliness, amenities, property conditions & facilities
Nice!
Stayed 1 night in Dec 2025

10/10 Excellent

Brittany

Stayed 1 night in Dec 2025

8/10 Good

Praveena

Stayed 1 night in Nov 2025

10/10 Excellent

Lucy

Stayed 1 night in Dec 2025

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