Cheap flights from SNA to GSP (John Wayne to Greenville-Spartanburg Intl.)

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Cheap Flights from SNA to GSP starting at $201 One Way, $417 Round Trip

Prices starting at $417 for return flights and $201 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$417 Roundtrip, found 2 days ago
$417
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $417 found 2 days ago
Tue, Jun 9 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$437 Roundtrip, found 2 days ago
$437
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 9 from Orange County to Greenville, returning Wed, Jun 17, priced at $437 found 2 days ago
Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$437 Roundtrip, found 2 days ago
$437
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $437 found 2 days ago
Tue, Jun 9 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$442 Roundtrip, found 2 days ago
$442
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Jun 9 from Orange County to Greenville, returning Wed, Jun 17, priced at $442 found 2 days ago
Mon, Jun 8 - Wed, Jun 17
SNA
Orange County
GSP
Greenville
$444 Roundtrip, found 2 days ago
$444
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Jun 8 from Orange County to Greenville, returning Wed, Jun 17, priced at $444 found 2 days ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
$77 nightly
The price is $84 total per night from May 14 to May 15
$84 total
May 14 - May 15
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,015 reviews)
Room was clean. Water pressure was low so toilets didn’t flush very well. Pool was dirty and I wouldn’t recommend swimming in it. Breakfast buffet was good. The rate is reasonable. Clemson was having graduation so everything in the area was expensive. Staying in Greenville was a cheaper alternative ...

Reviewed on May 10, 2026

Best Western Greenville Airport Inn
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$71 nightly
The price is $79 total per night from Jun 11 to Jun 12
$79 total
Jun 11 - Jun 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (692 reviews)
Smooth from day 1 till I checked out day 3

Reviewed on May 11, 2026

MainStay Suites Greenville Airport
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd Greenville SC
$71 nightly
The price is $79 total per night from May 14 to May 15
$79 total
May 14 - May 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Haywood Mall and Topgolf ...
8/10 Very Good! (441 reviews)
The room was dirty and nasty, bug crawling in the kitchen area and bathroom. They didn’t have any towels or wash clothes had to go to Walmart to purchase some. Noisy, ppl slamming and closing doors all through the night.

Reviewed on May 10, 2026

Woodspring Suites Greenville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
$121 nightly
The price is $133 total per night from Jun 4 to Jun 5
$133 total
Jun 4 - Jun 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (665 reviews)
Staff. Clean room. Comfortable and close to highway food etc.

Reviewed on May 4, 2026

Courtyard Greenville-Spartanburg by Marriott
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$104 nightly
The price is $114 total per night from May 17 to May 18
$114 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (788 reviews)
Very nice, well taken care of. Comfortable bed abd spacious room, shower was large and had a great shower head. Had a great choice of breakfast foofs to choose from. Will use Comfort Inn & Suites again.

Reviewed on May 7, 2026

Comfort Inn & Suites Greer - Greenville
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
$71 nightly
The price is $79 total per night from Jun 11 to Jun 12
$79 total
Jun 11 - Jun 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (692 reviews)
Smooth from day 1 till I checked out day 3

Reviewed on May 11, 2026

MainStay Suites Greenville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$114 nightly
The price is $125 total per night from May 24 to May 25
$125 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (844 reviews)
Our room was dirty upon arrival. Inside was very unkept and dirty. Stains and holes in the wall. No sheets for the pullout couch bed which was stained. One of the queen beds was literally blocking and aotting on the air unit. Thus making it very cold and uncomfortable for the person or persons occupying ...

Reviewed on May 3, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$104 nightly
The price is $114 total per night from May 17 to May 18
$114 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (788 reviews)
Very nice, well taken care of. Comfortable bed abd spacious room, shower was large and had a great shower head. Had a great choice of breakfast foofs to choose from. Will use Comfort Inn & Suites again.

Reviewed on May 7, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$114 nightly
The price is $125 total per night from May 24 to May 25
$125 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (844 reviews)
Our room was dirty upon arrival. Inside was very unkept and dirty. Stains and holes in the wall. No sheets for the pullout couch bed which was stained. One of the queen beds was literally blocking and aotting on the air unit. Thus making it very cold and uncomfortable for the person or persons occupying ...

Reviewed on May 3, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$78 nightly
The price is $85 total per night from Jun 7 to Jun 8
$85 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (352 reviews)
It amazes me that such an outdated and ill-kept facility charges over $100 per night. The room had dead bugs in the corner and stains on the bed cover. Thankfully I am glad to report there were no bed bugs in our room.

Reviewed on May 5, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SNA to Roger Milliken Field?
Unfortunately, there are no direct flights on this route. But American Airlines, United Airlines and Delta Air Lines can fly you from John Wayne Airport to Greenville-Spartanburg Intl. Airport (GSP) with only one stopover.
What is the shortest flight from John Wayne Airport to GSP?
The quickest you can fly from John Wayne Airport to Greenville-Spartanburg Intl. Airport (GSP) is 5 hours and 44 minutes. Slip a few things into your hand luggage to keep you amused, like a magazine or a portable board game.
How many hours flight from SNA to Roger Milliken Field?
On average, the journey from John Wayne Airport (SNA) to Roger Milliken Field takes 5 hours and 50 minutes. If you would like to be as comfortable as possible, consider upgrading your seat using miles or cash.
What airlines have the most flights from John Wayne Airport (SNA) to GSP?
You'll need to make one or more stopovers if you need to get from Santa Ana to Greenville. Right now, you won't find any airlines that offer nonstop flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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