Cheap flights from SAN to GSP (San Diego Intl. to Greenville-Spartanburg Intl.)

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Cheap Flights from SAN to GSP starting at $200 One Way, $389 Round Trip

Prices starting at $389 for return flights and $200 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, May 18 - Tue, May 19
SAN
San Diego
GSP
Greenville
$389 Roundtrip, found 5 days ago
$389
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Mon, May 18 from San Diego to Greenville, returning Tue, May 19, priced at $389 found 5 days ago
Mon, May 18 - Tue, May 19
SAN
San Diego
GSP
Greenville
$394 Roundtrip, found 5 days ago
$394
Roundtrip
found 5 days ago
Select United flight, departing Mon, May 18 from San Diego to Greenville, returning Tue, May 19, priced at $394 found 5 days ago
Mon, May 18 - Tue, May 19
SAN
San Diego
GSP
Greenville
$399 Roundtrip, found 5 days ago
$399
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, May 18 from San Diego to Greenville, returning Tue, May 19, priced at $399 found 5 days ago
Mon, May 18 - Tue, May 19
SAN
San Diego
GSP
Greenville
$404 Roundtrip, found 5 days ago
$404
Roundtrip
found 5 days ago
Select United flight, departing Mon, May 18 from San Diego to Greenville, returning Tue, May 19, priced at $404 found 5 days ago
Sat, May 16 - Mon, May 18
SAN
San Diego
GSP
Greenville
$415 Roundtrip, found 2 days ago
$415
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 16 from San Diego to Greenville, returning Mon, May 18, priced at $415 found 2 days ago

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
The price is $101 total per night from Mar 29 to Mar 30
$101 total
per night
Mar 29 - Mar 30
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,000 reviews)
Hotel is close to everything but feels quiet and secluded. Parking was ample and well lit. Lot is landscaped and clean and felt private even though it's right off the interstate. Staff was great - Vera at checkin was friendly, personable, attentive, and helpful & Tommie at checkout was equally pleasant ...

Reviewed on Mar 16, 2026

Hampton Inn & Suites Greenville Airport, SC
MainStay Suites Greenville Airport

MainStay Suites Greenville Airport

2.5 out of 5
2671 Dry Pocket Rd Greer SC
The price is $71 total per night from Apr 19 to Apr 20
$71 total
per night
Apr 19 - Apr 20
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (659 reviews)
Love it..didn't want to leave.

Reviewed on Mar 18, 2026

MainStay Suites Greenville Airport
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $125 total per night from Apr 5 to Apr 6
$125 total
per night
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (833 reviews)
Bath tub did not drain while showering. It is gross to shower in your dirty water😕

Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
The price is $94 total per night from Mar 29 to Mar 30
$94 total
per night
Mar 29 - Mar 30
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (770 reviews)
Clean room but bath cloth extremely thin. Adequate parking.

Reviewed on Mar 12, 2026

Comfort Inn & Suites Greer - Greenville
Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
The price is $109 total per night from Mar 22 to Mar 23
$109 total
per night
Mar 22 - Mar 23
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (647 reviews)
Yes, Internet good and friendly staff at front desk.

Reviewed on Mar 11, 2026

Courtyard Greenville-Spartanburg by Marriott
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $125 total per night from Apr 5 to Apr 6
$125 total
per night
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (833 reviews)
Bath tub did not drain while showering. It is gross to shower in your dirty water😕

Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $125 total per night from Apr 5 to Apr 6
$125 total
per night
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (833 reviews)
Bath tub did not drain while showering. It is gross to shower in your dirty water😕

Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
The price is $94 total per night from Mar 29 to Mar 30
$94 total
per night
Mar 29 - Mar 30
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (770 reviews)
Clean room but bath cloth extremely thin. Adequate parking.

Reviewed on Mar 12, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
The price is $125 total per night from Apr 5 to Apr 6
$125 total
per night
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (833 reviews)
Bath tub did not drain while showering. It is gross to shower in your dirty water😕

Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
The price is $76 total per night from Apr 19 to Apr 20
$76 total
per night
Apr 19 - Apr 20
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (337 reviews)
It

Reviewed on Feb 18, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAN to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from San Diego Intl. Airport (SAN) to GSP?
Traveling from SAN to Roger Milliken Field? Breaking up the trip is your one and only option as there are currently no carriers that service this route directly. However, American Airlines, United Airlines and Delta Air Lines offer the best alternative — a flight with just a single stopover.
What is the shortest flight from San Diego Airport to GSP?
Jetting from San Diego Airport to Roger Milliken Field takes at least 5 hours and 56 minutes. Savor a wine and watch a flick or two — this is a great chance to sit back and relax.
How many hours flight from San Diego Intl. Airport (SAN) to Greenville-Spartanburg Intl. Airport (GSP)?
On average, it takes 6 hours and 1 minute to journey from San Diego Airport to Roger Milliken Field. You'll be on board for quite some time, so take plenty of entertainment, like a newspaper or some crossword puzzles.
What airlines have the most flights from San Diego Airport to Roger Milliken Field?
If you want to find an airline that operates direct flights from San Diego Intl. Airport (SAN) to Roger Milliken Field, you're out of luck. You'll have to book a flight with at least one stopover to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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