$79 Cheap flight deals from Knoxville (TYS) to Destin (VPS)
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This Weekend's Flight Deals from Knoxville to Destin
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $79 One Way, $95 Round Trip from Knoxville to Destin
Prices starting at $95 for return flights and $79 for one-way flights to Destin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Destin economy flight packages
Homewood Suites by Hilton Destin
Oct 3 - Oct 6
Knoxville (TYS) to Fort Walton Beach (VPS)
Fort Walton Beach (VPS) to Knoxville (TYS)
Sea Oats Motel
Oct 3 - Oct 6
Knoxville (TYS) to Fort Walton Beach (VPS)
Fort Walton Beach (VPS) to Knoxville (TYS)
Reviewed on Aug 15, 2026
Gulf Terrace Getaway by Avantstay Shared Pool + Tennis Near Henderson Beach + Destin Commons
Oct 3 - Oct 6
Knoxville (TYS) to Fort Walton Beach (VPS)
Fort Walton Beach (VPS) to Knoxville (TYS)
Destin first class flight packages
Resort Condo Steps to Beach Pool, Hot Tub, Tennis, Golf Sandestin, Miramar Beach
Oct 3 - Oct 10
Knoxville (TYS) to Fort Walton Beach (VPS)
Emerald Breeze by Avantstay Shared Pool + Tennis Court + Balcony Dining + Near Beach and Harbor Boardwalk
Oct 3 - Oct 10
Knoxville (TYS) to Fort Walton Beach (VPS)
More About Flying To Destin from Knoxville
Route Information for Flights from Knoxville to Destin
Origin Airport IATA Code | TYS |
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Destination Airport IATA Code | VPS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Knoxville to Destin
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You can always find affordable flights from Knoxville to Destin on Orbitz. Use different airlines to book arrival and departure flights, take advantage of vacation package deals, and secure exclusive rewards.
Flights from Knoxville
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Knoxville Airports
Destin Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.