Beginning of main content

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Fares from $73 One Way, $184 Round Trip from Fort Myers to St. Louis

Prices starting at $184 for return flights and $73 for one-way flights to St. Louis were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Need A Hotel In St. Louis?

Hotels In Top St. Louis Neighborhoods

Stay Near Exciting St. Louis Attractions

More About Flying To St. Louis from Fort Myers

Route Information for Flights from Fort Myers to St. Louis

Origin Airport IATA CodeFMY
Destination Airport IATA CodeSTL
Distance980 mi
Direct Flight AirlinesSouthwest Airlines
Earliest Flight Arrival5:25PM UTC
Latest Flight Arrival11:30PM UTC

Fly from Fort Myers to St. Louis

If you'd like to explore a vibrant, Midwestern city that rests along the glistening shores of the Mississippi River, you can fly from Fort Myers to St. Louis in just under three hours. Your trip will begin when you take a car, taxi or bus to Southwest Florida International Airport (RSW), a modern facility on the Gulf Coast that handles over 230 flights per day.


While you are here, you can visit the St. Louis Zoo, which is home to a variety of exotic animals including polar bears, tigers and stingrays. The City Museum features an intriguing network of tunnels and interactive exhibits. Forest Park provides a lovely place for visitors to stroll through the grounds and enjoy a paddleboat ride.

Hints and tips

When you arrive at Lambert-St. Louis International Airport (STL), you can get to your destination via rental car, taxi, train, bus or hotel shuttle. St. Louis was established in the late 1700s and flourished as a main fur trading post. The average summer temperatures hover around 82 degrees, and winter averages are near 30 degrees. The St. Louis Earth Day Festival, Saint Louis Blues Week and the St. Louis Brewers Heritage Festival are just a taste of the events that occur in the city each year.

Flights from Fort Myers to St. Louis - Frequently Asked Questions

Are there non-stop flights from Fort Myers to St. Louis?

There is. Southwest Airlines offers direct flights from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to St. Louis, MO Airport (STL-Lambert-St. Louis Intl.), which makes jetting from Fort Myers to St. Louis a cinch.

What is the shortest flight from Fort Myers to St. Louis?

It can zip by in as little as 2 hours and 20 minutes. If you're of the opinion that your vacation hours should be spent 'vacationing' rather than flying, you'll enjoy the trip from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to St. Louis, MO Airport (STL-Lambert-St. Louis Intl.).

What airlines fly from Fort Myers to St. Louis most frequently?

Southwest Airlines offers the most services from Fort Myers to St. Louis, with 60 flights per month.

^Savings based on all package bookings with Flight + Hotel made on from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.