$329 Cheap flight deals from Pittsburgh (PIT) to Mission (MFE)
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Airfares from $329 One Way, Round Trip from Pittsburgh to Mission
Prices starting at for return flights and $329 for one-way flights to Mission were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mission economy flight packages
Lone Star Inn & Suites by OYO Harlingen TX
Nov 22 - Nov 29
Pittsburgh (PIT) to McAllen (MFE)
Reviewed on Sep 27, 2025
Americas Best Value Inn Harlingen
Nov 22 - Nov 29
Pittsburgh (PIT) to McAllen (MFE)
Reviewed on Sep 20, 2024
More About Flying To Mission from Pittsburgh
Route Information for Flights from Pittsburgh to Mission
Origin Airport IATA Code | PIT |
|---|---|
Destination Airport IATA Code | MFE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Pittsburgh to Mission
It has never been easier to find cheap Pittsburgh to Mission flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.
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Get the Best Deals on Pittsburgh to Mission Flights
Finding great deals on flights from Pittsburgh to Mission is a snap with Orbitz. With our guaranteed low prices, you don’t have to worry if you are getting the best prices on air tickets, hotels, and cruises. And with all that money you saved, you can enjoy your Mission vacation even more.
Pile Up Miles With Discount Air Tickets
Not only can you find great bargains on Pittsburgh to Mission flights, but you can rack up frequent flyer miles on the flights too. Enter your frequent flyer number on qualified flights when booking for Orbitz to see the miles pile up in your account.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.