$132 Cheap flight deals from Des Moines (DSM) to San Clemente (QLA)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Des Moines to San Clemente

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 10 - Sat, Oct 11
DSM
Des Moines Intl.
CLD
McClellan-Palomar
$669 Roundtrip, found 4 days ago
$669
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Des Moines Intl. to McClellan-Palomar, returning Sat, Oct 11, priced at $669 found 4 days ago

Airfares from $132 One Way, $261 Round Trip from Des Moines to San Clemente

Prices starting at $261 for return flights and $132 for one-way flights to San Clemente were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 13 - Tue, Jan 6
DSM
Des Moines
SNA
Orange County
$261 Roundtrip, found 1 day ago
$261
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Dec 13 from Des Moines to Orange County, returning Tue, Jan 6, priced at $261 found 1 day ago
Thu, Dec 4 - Sun, Dec 7
DSM
Des Moines
CLD
Carlsbad
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 4 from Des Moines to Carlsbad, returning Sun, Dec 7, priced at $263 found 1 day ago
Mon, Nov 24 - Wed, Dec 3
DSM
Des Moines
SNA
Orange County
$265 Roundtrip, found 3 hours ago
$265
Roundtrip
found 3 hours ago
Select Delta flight, departing Mon, Nov 24 from Des Moines to Orange County, returning Wed, Dec 3, priced at $265 found 3 hours ago
Tue, Feb 10 - Tue, Feb 24
DSM
Des Moines
SNA
Orange County
$266 Roundtrip, found 1 day ago
$266
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Feb 10 from Des Moines to Orange County, returning Tue, Feb 24, priced at $266 found 1 day ago
Fri, Nov 7 - Tue, Nov 11
DSM
Des Moines
CLD
Carlsbad
$267 Roundtrip, found 7 hours ago
$267
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Nov 7 from Des Moines to Carlsbad, returning Tue, Nov 11, priced at $267 found 7 hours ago

San Clemente economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hollywood Inn Suites Hotel
2.5-star property

Hollywood Inn Suites Hotel

8.2/10 Very Good! (1,565 reviews)

Nov 13 - Nov 17

4 night stay

Des Moines (DSM) to Los Angeles (LAX)

Southwest Airlines • Non-stop • Coach

Los Angeles (LAX) to Des Moines (DSM)

Delta • Non-stop • Coach
Price was $802, price is now $517 per person
$517
per person
found 1 day ago
Hotel itself is clean. There was a fresh paint and sometime a strong chemical smell in the room. I was ready to find a new hotel if I could have canceled this stay. There is no coffee pot in the room, not very much space to set anything out, few drawers to put anything away. There is a coffee and flavored water machine in the lobby. The coffee is very bland, much like drinking flavor water. Overall, it’s all in the photos you just need to look closely. The room is spacious, beds are comfortable. It appears the hotel was just renovated. By the area it is located, it was most likely a pay by the hour motel in the past. At least it was clean.

Reviewed on Aug 22, 2025

Glendale Hotel
2.5-star property

Glendale Hotel

8.4/10 Very Good! (2,745 reviews)

Nov 13 - Nov 17

4 night stay

Des Moines (DSM) to Los Angeles (LAX)

Southwest Airlines • Non-stop • Coach

Los Angeles (LAX) to Des Moines (DSM)

Delta • Non-stop • Coach
Save 100% on your flight
Price was $940, price is now $596 per person
$596
per person
found 1 day ago
Friendly & helpful staff.

Reviewed on Mar 6, 2025

Fleur Noire Hotel - 21 and Over
3.5-star property

Fleur Noire Hotel - 21 and Over

9.6/10 Exceptional! (824 reviews)

Nov 14 - Nov 17

3 night stay

Des Moines (DSM) to Los Angeles (LAX)

Southwest Airlines • Non-stop • Coach

Los Angeles (LAX) to Des Moines (DSM)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $1,243, price is now $799 per person
$799
per person
found 14 hours ago
This was a nice enough stay overall, but a lot different than what I was expecting. First, there was a discrepancy in what room type Orbitz portrayed as being booked and what was actually booked. I booked a Premium King room through Orbitz; this apparently did not actually mean a Premium King as described on the hotel's website, but rather a studio king room which is more in-line with the Classic King (but also not because the hotel attendant said it's the Classic King room which is larger and comes with a separated dining area). Upon bringing it to the hotel staff's attention a few days into my stay, I was informed this was a 3rd-party booking site problem and basically that was that. Would that have ultimately made a difference in the other quirky aspects of my stay? Maybe, maybe not. The property has been through a lot since its inception, despite its renovations (read: paint and fixtures). There were several issues with the main entry door, bathroom door, and large window in our room, primarily w/ incomplete closure and weather-stripping. The bathroom door was wonky such that it couldn't close all the way and if you forced it, you're likely to be stuck. Lack of good exterior door/window seal allowed worms into the unit every evening! Did NOT enjoy that whatsoever, and no towels against the door could stop them. TP and towels were very thin, breakfast was OK. Bad industrial smells in courtyard some days. Restaurant next door can be very loud on weekends at close.

Reviewed on Sep 25, 2025

Don't see what you're looking for?
See all available trips from Des Moines to San Clemente
View all trips

More About Flying To San Clemente from Des Moines

Route Information for Flights from Des Moines to San Clemente

Origin Airport IATA Code
DSM
Destination Airport IATA Code
QLA
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to San Clemente

When you’re searching for Des Moines to San Clemente flights for your family vacation, check out the guaranteed low prices at Orbitz. If you are looking for the best prices on hotels too, you’ll be sure to find great deals to suit your budget. You’ll also benefit from the following features:

Suitable Schedules

Orbitz simplifies the process of finding and booking budget flights from Des Moines to San Clemente. Since we monitor hundreds of flight fares, you can compare several flights from a range of different airlines to find the best fares and most suitable departure and arrival times. Mix and match your departure and return flight for even more discounts and travel flexibility.

Mobile Apps

Taking a lunch break or waiting to pick up the kids? Orbitz’s cutting-edge mobile tools will help you search for cheap Des Moines to San Clemente flights anywhere you are. Get exclusive mobile deals on flights, hotels, vacation packages, and cruises too.

Flight Alerts

Orbitz won’t leave you wondering whether your flight will take off on time. We can send you free alerts about your flights from Des Moines to San Clemente to your mobile phone and email. Whether your flights from Des Moines to San Clemente are running just a few minutes to a few hours late, we will let you know.

Miles and Points

If you travel regularly, you can still earn miles and points when you book qualifying Des Moines to San Clemente flights. Enter your frequent flyer number with your reservation to see the miles rack up.

More Destinations

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.