$137 Cheap flight deals from Myrtle Beach (MYR) to Middlesboro (TYS)
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Airfares from $137 One Way, $277 Round Trip from Myrtle Beach to Middlesboro
Prices starting at $277 for return flights and $137 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages
La Quinta Inn & Suites by Wyndham Knoxville Airport
Oct 7 - Oct 14
Myrtle Beach (MYR) to Knoxville (TYS)
Knoxville (TYS) to Myrtle Beach (MYR)
Hilton Knoxville Airport
Oct 7 - Oct 14
Myrtle Beach (MYR) to Knoxville (TYS)
Knoxville (TYS) to Myrtle Beach (MYR)
Reviewed on Aug 25, 2026
Element by Marriott Knoxville West
Oct 7 - Oct 14
Myrtle Beach (MYR) to Knoxville (TYS)
Knoxville (TYS) to Myrtle Beach (MYR)
More About Flying To Middlesboro from Myrtle Beach
Route Information for Flights from Myrtle Beach to Middlesboro
Origin Airport IATA Code | MYR |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Myrtle Beach to Middlesboro
Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Myrtle Beach to Middlesboro to give you a travel experience that is second to none.
Bargain Travel at Your Fingertips
Orbitz provides the cheapest fares from Myrtle Beach to Middlesboro. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.
Modern Tools for Fast-Paced Travel
Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Myrtle Beach to Middlesboro flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Myrtle Beach to Middlesboro and choose a range of cheap hotels to stay in.
Enjoy Stress-Free Travel with Flight Alerts
Once you have booked your flights from Myrtle Beach to Middlesboro on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Myrtle Beach to Middlesboro flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.
Frequent Flyer Program
For loyal Orbitz customers who fly from Myrtle Beach to Middlesboro the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.
Flights from Myrtle Beach
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Myrtle Beach Airports
Middlesboro Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.