$135 Cheap flight deals from Myrtle Beach (MYR) to Middlesboro (TYS)
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Airfares from $135 One Way, $307 Round Trip from Myrtle Beach to Middlesboro
Prices starting at $307 for return flights and $135 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages
River Edge Inn
Apr 2 - Apr 8
Myrtle Beach (MYR) to Knoxville (TYS)
Reviewed on Nov 9, 2025
Gatlinburg Town Square
Apr 2 - Apr 8
Myrtle Beach (MYR) to Knoxville (TYS)
Reviewed on Apr 5, 2025
The Timber at Holly Branch
Apr 2 - Apr 8
Myrtle Beach (MYR) to Knoxville (TYS)
Reviewed on Oct 3, 2025
More About Flying To Middlesboro from Myrtle Beach
Route Information for Flights from Myrtle Beach to Middlesboro
Origin Airport IATA Code | MYR |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Myrtle Beach to Middlesboro
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Myrtle Beach Airports
Middlesboro Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.