$132 Cheap flight deals from Asunción (ASU) to Santiago (SCL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Asunción to Santiago

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 24 - Sat, Oct 31
ASU
Silvio Pettirossi Intl.
SCL
Arturo Merino Benitez
$557 Roundtrip, found 2 days ago
$557
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sat, Oct 24 from Silvio Pettirossi Intl. to Arturo Merino Benitez, returning Sat, Oct 31, priced at $557 found 2 days ago

Airfares from $132 One Way, $247 Round Trip from Asunción to Santiago

Prices starting at $247 for return flights and $132 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 5 - Wed, Nov 11
ASU
Asunción
SCL
Santiago
$247 Roundtrip, found 1 day ago
$247
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, Nov 5 from Asunción to Santiago, returning Wed, Nov 11, priced at $247 found 1 day ago
Mon, Mar 22 - Sun, Mar 28
ASU
Asunción
SCL
Santiago
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Mar 22 from Asunción to Santiago, returning Sun, Mar 28, priced at $298 found 2 days ago
Mon, Mar 22 - Sun, Mar 28
ASU
Asunción
SCL
Santiago
$308 Roundtrip, found 2 days ago
$308
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Mar 22 from Asunción to Santiago, returning Sun, Mar 28, priced at $308 found 2 days ago
Thu, Jan 7 - Mon, Jan 11
ASU
Asunción
SCL
Santiago
$312 Roundtrip, found 1 day ago
$312
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, Jan 7 from Asunción to Santiago, returning Mon, Jan 11, priced at $312 found 1 day ago
Fri, Feb 12 - Wed, Feb 17
ASU
Asunción
SCL
Santiago
$318 Roundtrip, found 3 days ago
$318
Roundtrip
found 3 days ago
Select Aerolineas Argentinas flight, departing Fri, Feb 12 from Asunción to Santiago, returning Wed, Feb 17, priced at $318 found 3 days ago

Santiago economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Capital Bellet
3.0-star property

Hotel Capital Bellet

9.2/10 Wonderful! (1,006 reviews)

Nov 26 - Nov 29

3 night stay

Asuncion (ASU) to Santiago (SCL)

LATAM Airlines Group • Roundtrip • Coach
Price was $503, price is now $397 per person
$397
per person
found 1 day ago
Great accommodation in a safe and convenient location. The staff are polite and attentive and the hotel is kept clean and modern whilst reasonably priced for the location. I would happily stay there again.

Reviewed on Oct 19, 2026

Hotel Director Vitacura
3.5-star property

Hotel Director Vitacura

9/10 Wonderful! (682 reviews)

Nov 26 - Nov 29

3 night stay

Asuncion (ASU) to Santiago (SCL)

LATAM Airlines Group • Roundtrip • Coach
Price was $563, price is now $440 per person
$440
per person
found 1 day ago
I like this place we'll locate it

Reviewed on Oct 3, 2026

ICON Hotel
4.0-star property

ICON Hotel

8.6/10 Excellent! (1,002 reviews)

Nov 26 - Nov 29

3 night stay

Asuncion (ASU) to Santiago (SCL)

LATAM Airlines Group • Roundtrip • Coach
Price was $571, price is now $451 per person
$451
per person
found 1 day ago
Realmente tienen que renovar personal, pesima atencion, pesimas condiciones de la propiedad, muy mal hospitality, room service con muy poca variedad y mala cocina, habitaciones chicas y anticuadas, television que apenas funciona e inventar lo que sea para intentar multarte y sacarte mas dinero durante la estancia, recomendaría cualquier otro.

Reviewed on Oct 18, 2026

Don't see what you're looking for?
See all available trips from Asunción to Santiago
View all trips

More About Flying To Santiago from Asunción

Route Information for Flights from Asunción to Santiago

Origin Airport IATA Code
ASU
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Asunción to Santiago

Rack up your savings with low-cost flights from Asunción to Santiago with Orbitz On-the-Go. Orbitz On-the-Go offers mobile-only deals and cutting edge mobile tools to help you find bargain flights from Asunción to Santiago.

Mobile-Only Deals on Asunción to Santiago flights

Find guaranteed low prices on Asunción to Santiago flights using Orbitz On-the-Go. You can book discount domestic flights from Asunción to Santiago, and international tickets on Asunción to Santiago flights using our mobile site and apps.

Free Alerts Are No Surprise

Not only will you find cheap tickets on flights from Asunción to Santiago, but Orbitz free alerts will keep you up to speed on flight status, plus gate and baggage claim details. Receive instant updates via your choice of email, voice or text. Orbitz keeps you easily on task and on budget.

Share Itineraries on Flights from Asunción to Santiago

Are you traveling for business, pleasure or a combination of both? Keep family, friends and business contacts posted on flight and gate info. Just use MyTrips for iPhone, Android and web phones like Blackberry and Windows.

Add Smiles to Your Miles with Sales and Deals on Asunción to Santiago Flights

Travel planning is easy when you store your frequent flyer and loyalty program information on your Orbitz account. Then snag a low-fare air ticket on Asunción to Santiago flights, and you’re done. No muss, no fuss. Your miles will fly by with Orbitz On-the-Go cutting edge mobile tools and guaranteed low prices.

Frequently asked questions

Are there non-stop flights from Asuncion to Santiago?
There is. LATAM Airlines offers direct flights from ASU to Nuevo Pudahuel Airport, which makes traveling from Asuncion to Santiago a piece of cake.
What is the shortest flight from Asuncion to Santiago?
With the flight from Asuncion (ASU-Silvio Pettirossi Intl.) to SCL taking a minimum of 4 hours and 10 minutes, there's plenty of time to enjoy the flying experience. Treat yourself to an in-flight wine or two and sink into your seat with a riveting book or movie.
What airlines fly from Asuncion to Santiago most frequently?
If you're looking for the airline with the most flights from Asuncion to Santiago, LATAM Airlines is your best bet. This respected airline operates 13 monthly flights along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.