
$38 Cheap flight deals from Antofagasta (ANF) to Santiago (SCL)
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Airfares from $38 One Way, $97 Round Trip from Antofagasta to Santiago
Prices starting at $97 for return flights and $38 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santiago economy flight packages

LOFT Hotel by Sommelier Hoteles
Dec 4 - Dec 7
Antofagasta (ANF) to Santiago (SCL)
Santiago (SCL) to Antofagasta (ANF)
Reviewed on Oct 26, 2026

Hotel Nodo - El primer hotel de negocios en Chile
Dec 4 - Dec 7
Antofagasta (ANF) to Santiago (SCL)
Santiago (SCL) to Antofagasta (ANF)
Reviewed on Oct 17, 2026

More About Flying To Santiago from Antofagasta
Route Information for Flights from Antofagasta to Santiago
Origin Airport IATA Code | ANF |
|---|---|
Destination Airport IATA Code | SCL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Antofagasta to Santiago
When you’re ready to take your next trip, get the most affordable prices on flights from Antofagasta to Santiago with Orbitz! The guaranteed low prices and cutting-edge mobile tools on Orbits make it easy for you to plan your next great vacation.
Keep Up With Sudden Flight Changes
As any traveler knows, air travel can suddenly be temporarily halted due to service disruptions. Along with offering the best fares for flights from Antofagasta to Santiago, Orbitz also offers free mobile phone and email alerts that help you keep up with sudden changes to your flight plans. Choose from email, text, or voice message alerts.
Get Great Prices for Antofagasta to Santiago Flights
Orbitz features both an Android app and an iPhone app to give you the lowest prices for Antofagasta to Santiago flights. Use these mobile apps to get updates on your flight, the details of your itinerary, and to learn about available hotel deals in the area.
Fly for Less and Earn Miles
Did you know you can earn miles and points for your frequent flyer program with Orbitz? To do this with specific flights from Antofagasta to Santiago, enter your frequent flyer account number when you book your ticket online. For even more convenience, keep a record of your loyalty travel program numbers directly with Orbitz by storing them in your account profile. This way, you can add your account numbers to your next reservation for Antofagasta to Santiago flights automatically without the annoying hassle of having to look them up.
Frequently asked questions
Flights to Santiago
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Flights from Antofagasta
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

