$33 Cheap flight deals from La Serena (LSC) to Santiago (SCL)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from La Serena to Santiago

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 24 - Sun, Oct 26
LSC
La Florida
SCL
Arturo Merino Benitez
$165 Roundtrip, found 1 day ago
$165
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Fri, Oct 24 from La Florida to Arturo Merino Benitez, returning Sun, Oct 26, priced at $165 found 1 day ago

Airfares from $33 One Way, $69 Round Trip from La Serena to Santiago

Prices starting at $69 for return flights and $33 for one-way flights to Santiago were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Nov 14 - Fri, Nov 21
LSC
La Serena
SCL
Santiago
$69 Roundtrip, found 3 days ago
$69
Roundtrip
found 3 days ago
Select SKY AIRLINE flight, departing Fri, Nov 14 from La Serena to Santiago, returning Fri, Nov 21, priced at $69 found 3 days ago
Thu, Nov 13 - Mon, Nov 17
LSC
La Serena
SCL
Santiago
$70 Roundtrip, found 4 days ago
$70
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, Nov 13 from La Serena to Santiago, returning Mon, Nov 17, priced at $70 found 4 days ago
Tue, Nov 18 - Sun, Nov 23
LSC
La Serena
SCL
Santiago
$73 Roundtrip, found 1 day ago
$73
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Tue, Nov 18 from La Serena to Santiago, returning Sun, Nov 23, priced at $73 found 1 day ago
Tue, Nov 18 - Sun, Nov 23
LSC
La Serena
SCL
Santiago
$74 Roundtrip, found 1 day ago
$74
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Tue, Nov 18 from La Serena to Santiago, returning Sun, Nov 23, priced at $74 found 1 day ago
Thu, Nov 13 - Mon, Nov 17
LSC
La Serena
SCL
Santiago
$75 Roundtrip, found 4 days ago
$75
Roundtrip
found 4 days ago
Select SKY AIRLINE flight, departing Thu, Nov 13 from La Serena to Santiago, returning Mon, Nov 17, priced at $75 found 4 days ago

More About Flying To Santiago from La Serena

Route Information for Flights from La Serena to Santiago

Origin Airport IATA Code
LSC
Destination Airport IATA Code
SCL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

La Serena to Santiago

Orbitz gives you great deals on your flights from La Serena to Santiago. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.

We Offer Great Travel Deals and Discounts

When you book flights from La Serena to Santiago with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on La Serena to Santiago flights for your trip—whether you are traveling for business or for fun with your family.

Enjoy Savings on Last-Minute Flights

If you are looking for a discount price on last-minute flights from La Serena to Santiago, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on La Serena to Santiago flights that fit your budget and your itinerary for the perfect trip.

Full-Service Mobile Apps

Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on La Serena to Santiago flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from La Serena to Santiago and review gate and baggage claim details too.

Frequently asked questions

Are there non-stop flights from La Serena to Santiago?
Fasten your seat belt and enjoy a relaxing flight with one of the 3 airlines that fly straight from La Florida Airport (LSC) to Santiago (SCL-Arturo Merino Benitez). We've complied a list of popular carriers to book with:

  • LATAM Airlines
  • Sky Airline
  • JetSmart

What is the shortest flight from La Serena to Santiago?
The journey from La Serena to Santiago can be as fast as 47 minutes. With a leisurely flight time like this, why not book a spontaneous getaway?
What airlines fly from La Serena to Santiago most frequently?
Check out LATAM Airlines (LA). This airline offers some of the most frequent flights from La Serena La Florida Airport to SCL. It operates 134 services on this route each month and is popular with passengers. Sky Airline (H2) will also get you to your destination in comfort and style. Offering 65 flights every month between La Serena and Santiago, it's another quality airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.