$144 Cheap flight deals from Charleston (CHS) to Middlesboro (TYS)
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This Weekend's Flight Deals from Charleston to Middlesboro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $144 One Way, $287 Round Trip from Charleston to Middlesboro
Prices starting at $287 for return flights and $144 for one-way flights to Middlesboro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Middlesboro economy flight packages
Club Wyndham Smoky Mountains
Dec 7 - Dec 10
Charleston (CHS) to Knoxville (TYS)
Knoxville (TYS) to Charleston (CHS)
Reviewed on Oct 24, 2026
Margaritaville Island Hotel
Dec 7 - Dec 10
Charleston (CHS) to Knoxville (TYS)
Knoxville (TYS) to Charleston (CHS)
Club Wyndham Great Smokies Lodge
Dec 7 - Dec 10
Charleston (CHS) to Knoxville (TYS)
Knoxville (TYS) to Charleston (CHS)
Reviewed on Oct 25, 2026
More About Flying To Middlesboro from Charleston
Route Information for Flights from Charleston to Middlesboro
Origin Airport IATA Code | CHS |
|---|---|
Destination Airport IATA Code | TYS |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Charleston to Middlesboro
Grab great fares on Charleston to Middlesboro flights with Orbitz, your #1 source for discount international and domestic air tickets. Our cutting-edge mobile tools and great online search functionality make booking your next budget trip a breeze.
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Flights from Charleston
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Charleston Airports
Middlesboro Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.