Cheap flights from SDF to SYR (Louisville Intl. to Hancock Intl.)

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Cheap Flights from SDF to SYR starting at $269 One Way, $395 Round Trip

Prices starting at $395 for return flights and $269 for one-way flights to Hancock Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, May 19 - Tue, May 26
SDF
Louisville
SYR
Syracuse
$395 Roundtrip, found 3 hours ago
$395
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, May 19 from Louisville to Syracuse, returning Tue, May 26, priced at $395 found 3 hours ago
Tue, May 19 - Tue, May 26
SDF
Louisville
SYR
Syracuse
$395 Roundtrip, found 3 hours ago
$395
Roundtrip
found 3 hours ago
Select United flight, departing Tue, May 19 from Louisville to Syracuse, returning Tue, May 26, priced at $395 found 3 hours ago
Tue, May 19 - Tue, May 26
SDF
Louisville
SYR
Syracuse
$395 Roundtrip, found 3 hours ago
$395
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, May 19 from Louisville to Syracuse, returning Tue, May 26, priced at $395 found 3 hours ago
Tue, Jun 23 - Sun, Jun 28
SDF
Louisville
SYR
Syracuse
$398 Roundtrip, found 2 days ago
$398
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jun 23 from Louisville to Syracuse, returning Sun, Jun 28, priced at $398 found 2 days ago
Tue, May 19 - Tue, May 26
SDF
Louisville
SYR
Syracuse
$400 Roundtrip, found 3 hours ago
$400
Roundtrip
found 3 hours ago
Select United flight, departing Tue, May 19 from Louisville to Syracuse, returning Tue, May 26, priced at $400 found 3 hours ago

Hotel Ideas near Hancock Intl.

Airport Hotels near Hancock Intl.

Comfort Inn & Suites Syracuse-Carrier Circle

Comfort Inn & Suites Syracuse-Carrier Circle

2.5 out of 5
6491 Thompson Rd Syracuse NY
$84 nightly
The price is $98 total per night from May 24 to May 25
$98 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,433 reviews)
All good

Reviewed on May 17, 2026

Comfort Inn & Suites Syracuse-Carrier Circle
Hotel Concord Syracuse, an Ascend Collection Hotel

Hotel Concord Syracuse, an Ascend Collection Hotel

2.5 out of 5
6605 Old Collamer Rd S. East Syracuse NY
$86 nightly
The price is $101 total per night from May 24 to May 25
$101 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in East Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.4/10 Good! (1,031 reviews)
There does not seem to be any housekeeping. The room just came with one set of towels for a 6 night stay. They also do not come in to take out the garbage during the stay. The staff was friendly at the front desk

Reviewed on May 17, 2026

Hotel Concord Syracuse, an Ascend Collection Hotel
LivAway Suites- Syracuse

LivAway Suites- Syracuse

2 out of 5
6595 Thompson Rd Syracuse NY
$89 nightly
The price is $104 total per night from May 18 to May 19
$104 total
May 18 - May 19
Total with taxes and fees
Stay at this hotel in Syracuse. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Destiny USA and JMA Wireless Dome are located ...
8.6/10 Excellent! (951 reviews)
Great stay. Definitely recommend it.

Reviewed on May 17, 2026

LivAway Suites- Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Syracuse

Holiday Inn Express Syracuse Airport by IHG

Holiday Inn Express Syracuse Airport by IHG

2.5 out of 5
5418 South Bay Road North Syracuse NY
$135 nightly
The price is $155 total per night from May 25 to May 26
$155 total
May 25 - May 26
Total with taxes and fees
Stay at this hotel in North Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,001 reviews)
No

Reviewed on May 12, 2026

Holiday Inn Express Syracuse Airport by IHG
Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG

3.5 out of 5
400 7th North St. North Syracuse NY
$134 nightly
The price is $154 total per night from May 31 to Jun 1
$154 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in North Syracuse. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
8.4/10 Very Good! (1,003 reviews)
There were multiple stains on the ceiling. Paid for a room with small kitchen however there were no utensils cups or glasses. Had to request cleaning as they missed two days of refreshing towels and taking out trash. Disappointed as prices were high due to multiple college graduation but inexcusable ...

Reviewed on May 16, 2026

Holiday Inn & Suites Syracuse Airport - Liverpool by IHG
Red Carpet Inn North Syracuse

Red Carpet Inn North Syracuse

2 out of 5
2914 Brewerton Rd North Syracuse NY
$70 nightly
The price is $80 total per night from May 28 to May 29
$80 total
May 28 - May 29
Total with taxes and fees
Stay at this hotel in North Syracuse. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,005 reviews)
Adequate - bathroom relatively clean - just a musty older place but I slept pretty well on the bed.

Reviewed on May 15, 2026

Red Carpet Inn North Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Syracuse Hotels With Airport Transportation

Surestay Plus by Best Western Syracuse Airport Htl

Surestay Plus by Best Western Syracuse Airport Htl

2.5 out of 5
900 Colonel Eileen Collins Boulevard North Syracuse NY
Stay at this property in North Syracuse. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Destiny USA and JMA Wireless Dome are located ...
7.4/10 Good! (1,000 reviews)
It is very close to the airport and easy to get to. The staff was very eager to help us in every way. They were pleasant and made sure everything was good

Reviewed on Mar 27, 2020

Get rates
Surestay Plus by Best Western Syracuse Airport Htl
Candlewood Suites - Syracuse Airport by IHG

Candlewood Suites - Syracuse Airport by IHG

2.5 out of 5
5414 South Bay Road Town of Salina North Syracuse NY
$89 nightly
The price is $102 total per night from May 24 to May 25
$102 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in North Syracuse. Enjoy free WiFi, free parking, and a free airport shuttle. Popular attractions Destiny USA and ...
6.2/10 (1,007 reviews)
I stayed in a renovated unit which I appreciated. Everything was clean and in its own place. My only issue was the roach that came out at night. The property is technically near some woods and they’re renovating the property so the roach could’ve came from a multitude of places. I only saw one so ...

Reviewed on May 11, 2026

Candlewood Suites - Syracuse Airport by IHG
Comfort Inn & Suites Airport

Comfort Inn & Suites Airport

4 out of 5
6701 Buckley Rd North Syracuse NY
Book a stay at this family-friendly inn in North Syracuse. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Popular attractions Destiny USA and ...
6.8/10 (1,000 reviews)
Worse Hotel Ever
When I first got there the woman at the front desk was VERY rude with an attitude. It was dark all the way to finding your room. First thing I wanted was to take a nice hot shower after a day at the beach. Let it run for SEVERAL+ minutes and water was ice cold and didn’t even get warm. On our way ...

Reviewed on Jul 2, 2020

Get rates
Comfort Inn & Suites Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Syracuse Hotels

Red Carpet Inn North Syracuse

Red Carpet Inn North Syracuse

2 out of 5
2914 Brewerton Rd North Syracuse NY
$70 nightly
The price is $80 total per night from May 28 to May 29
$80 total
May 28 - May 29
Total with taxes and fees
Stay at this hotel in North Syracuse. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,005 reviews)
Adequate - bathroom relatively clean - just a musty older place but I slept pretty well on the bed.

Reviewed on May 15, 2026

Red Carpet Inn North Syracuse
Candlewood Suites - Syracuse Airport by IHG

Candlewood Suites - Syracuse Airport by IHG

2.5 out of 5
5414 South Bay Road Town of Salina North Syracuse NY
$89 nightly
The price is $102 total per night from May 24 to May 25
$102 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in North Syracuse. Enjoy free WiFi, free parking, and a free airport shuttle. Popular attractions Destiny USA and ...
6.2/10 (1,007 reviews)
I stayed in a renovated unit which I appreciated. Everything was clean and in its own place. My only issue was the roach that came out at night. The property is technically near some woods and they’re renovating the property so the roach could’ve came from a multitude of places. I only saw one so ...

Reviewed on May 11, 2026

Candlewood Suites - Syracuse Airport by IHG
Surestay Plus by Best Western Syracuse Airport Htl

Surestay Plus by Best Western Syracuse Airport Htl

2.5 out of 5
900 Colonel Eileen Collins Boulevard North Syracuse NY
Stay at this property in North Syracuse. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Destiny USA and JMA Wireless Dome are located ...
7.4/10 Good! (1,000 reviews)
It is very close to the airport and easy to get to. The staff was very eager to help us in every way. They were pleasant and made sure everything was good

Reviewed on Mar 27, 2020

Get rates
Surestay Plus by Best Western Syracuse Airport Htl
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Syracuse

Comfort Inn & Suites Airport

Comfort Inn & Suites Airport

4 out of 5
6701 Buckley Rd North Syracuse NY
Book a stay at this family-friendly inn in North Syracuse. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Popular attractions Destiny USA and ...
6.8/10 (1,000 reviews)

Families like: Indoor pool, game room, cribs, rollaway beds

Worse Hotel Ever
When I first got there the woman at the front desk was VERY rude with an attitude. It was dark all the way to finding your room. First thing I wanted was to take a nice hot shower after a day at the beach. Let it run for SEVERAL+ minutes and water was ice cold and didn’t even get warm. On our way ...

Reviewed on Jul 2, 2020

Get rates
Comfort Inn & Suites Airport
Surestay Plus by Best Western Syracuse Airport Htl

Surestay Plus by Best Western Syracuse Airport Htl

2.5 out of 5
900 Colonel Eileen Collins Boulevard North Syracuse NY
Stay at this property in North Syracuse. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Destiny USA and JMA Wireless Dome are located ...
7.4/10 Good! (1,000 reviews)
It is very close to the airport and easy to get to. The staff was very eager to help us in every way. They were pleasant and made sure everything was good

Reviewed on Mar 27, 2020

Get rates
Surestay Plus by Best Western Syracuse Airport Htl
Red Carpet Inn North Syracuse

Red Carpet Inn North Syracuse

2 out of 5
2914 Brewerton Rd North Syracuse NY
$70 nightly
The price is $80 total per night from May 28 to May 29
$80 total
May 28 - May 29
Total with taxes and fees
Stay at this hotel in North Syracuse. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,005 reviews)
Adequate - bathroom relatively clean - just a musty older place but I slept pretty well on the bed.

Reviewed on May 15, 2026

Red Carpet Inn North Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SDF to SYR Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from SDF to SYR?
As you can't fly nonstop from Louisville Intl. Airport (SDF) to Hancock Intl. Airport (SYR) at this point in time, a flight with a single stopover is your next best option. American Airlines, Delta Air Lines and United Airlines are respected airlines that operate on this route.
What is the shortest flight from SDF to SYR?
From Louisville, the thrilling sights and sounds of Syracuse are 3 hours and 55 minutes away. Secure your favorite seat, or maybe even one with more legroom, and get to your destination in total comfort.
How many hours flight from Louisville Muhammad Ali Intl. Airport to Syracuse Hancock Intl. Airport?
It usually takes around 3 hours and 59 minutes to travel from SDF to Syracuse Hancock Intl. Airport. You'll be sitting down for a decent amount of time, so bring your own entertainment, like a good read or a podcast.
What airlines have the most flights from SDF to SYR?
Unfortunately there are no airlines flying direct from Louisville Muhammad Ali Intl. Airport to Hancock Intl. Airport (SYR). Do your research and reserve a multi or single-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.