Cheap flights from MHT to GSP (Manchester-Boston Regional to Greenville-Spartanburg Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MHT to GSP starting at $139 One Way, $271 Round Trip

Prices starting at $271 for return flights and $139 for one-way flights to Greenville-Spartanburg Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Greenville-Spartanburg Intl.

Airport Hotels near Greenville-Spartanburg Intl.

Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC

2.5 out of 5
128 The Parkway Greenville SC
$92 nightly
The price is $101 total per night from Mar 8 to Mar 9
$101 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,001 reviews)
Very clean room. Excellent, friendly staff, very helpful.

Reviewed on Feb 27, 2026

Hampton Inn & Suites Greenville Airport, SC
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
$72 nightly
The price is $79 total per night from Mar 1 to Mar 2
$79 total
Mar 1 - Mar 2
Total with taxes and fees
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,001 reviews)
The pillows were horrid!!! There were 4 pillows on the bed and they were all 12 x 12 inches and extremely hard. I am not sure why you would expect people use these for sleep?!?! The room was clean but the door opened to an open porch that lead down the stairs and to the back of the parking lot. It ...

Reviewed on Feb 24, 2026

Best Western Greenville Airport Inn
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
$122 nightly
The price is $134 total per night from Mar 8 to Mar 9
$134 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (628 reviews)
Room was very nice. I was charged twice for my stay even though I paid online and it took almost 7 days to refund my money after they finally realized the oversight!

Reviewed on Feb 24, 2026

Greenville Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Greenville

Courtyard Greenville-Spartanburg by Marriott

Courtyard Greenville-Spartanburg by Marriott

3 out of 5
115 The Pkwy Greer SC
$100 nightly
The price is $110 total per night from Mar 8 to Mar 9
$110 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (642 reviews)
Wonderful stay!

Reviewed on Feb 5, 2026

Courtyard Greenville-Spartanburg by Marriott
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$107 nightly
The price is $118 total per night from Mar 22 to Mar 23
$118 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (830 reviews)
Room was spotless, staff was friendly.

Reviewed on Feb 26, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
$99 nightly
The price is $109 total per night from Mar 15 to Mar 16
$109 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,000 reviews)
The check-in was efficient and the staff was friendly. The room was very nice and clean as well as the amenities. The ice machine on our hall was broken so we had to go to another floor and the breakfast option was too high compared to other hotels we've stayed in. Overall, it was a pretty good ...

Reviewed on Feb 24, 2026

Hilton Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Greenville Hotels With Airport Transportation

Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$107 nightly
The price is $118 total per night from Mar 22 to Mar 23
$118 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (830 reviews)
Room was spotless, staff was friendly.

Reviewed on Feb 26, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

2.5 out of 5
1315 W Wade Hampton Blvd Greer SC
$90 nightly
The price is $99 total per night from Mar 8 to Mar 9
$99 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (763 reviews)
The staff was very friendly, great breakfast and the room was very clean. Great stay.

Reviewed on Feb 27, 2026

Comfort Inn & Suites Greer - Greenville
Holiday Inn Express & Suites Greenville Airport by IHG

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 out of 5
2681 Dry Pocket Road Greer SC
$107 nightly
The price is $118 total per night from Mar 22 to Mar 23
$118 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (830 reviews)
Room was spotless, staff was friendly.

Reviewed on Feb 26, 2026

Holiday Inn Express & Suites Greenville Airport by IHG
Quality Inn Greer - Greenville

Quality Inn Greer - Greenville

2.5 out of 5
611 W Wade Hampton Blvd Greer SC
$84 nightly
The price is $92 total per night from Mar 29 to Mar 30
$92 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Greer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (337 reviews)
It

Reviewed on Feb 18, 2026

Quality Inn Greer - Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MHT to GSP Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MHT Address & GPS
Address:
One Airport Road
Manchester NH, 03103
United States
IATA Code:
MHT
Longitude:
-71.438439
Latitude:
42.927862
Time Zone:
America/New_York
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from MHT to GSP?
Nonstop flights aren't an option when it comes to getting from Manchester Airport to GSP. However, there are numerous carriers that service this route with just a single stopover, including American Airlines, Southwest Airlines and United Airlines.
What is the shortest flight from Manchester Airport to GSP?
Getting from MHT to Roger Milliken Field takes at least 3 hours and 32 minutes. Indulge in a wine and watch a show or two — this is a great chance to simply relax.
How many hours flight from Manchester Airport to Roger Milliken Field?
It typically takes about 3 hours and 40 minutes to jet from Manchester Airport to GSP. You'll be sitting down for a decent length of time, so consider bringing your own entertainment, like a novel or your travel journal.
What airlines have the most flights from Manchester Airport to GSP?
You'll have to make at least one stopover if you need to get from Manchester to Greenville. Unfortunately, you won't find any airlines that have nonstop flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore