$144 Cheap flight deals from Knoxville (TYS) to Edwardsville (STL)
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Airfares from $144 One Way, $567 Round Trip from Knoxville to Edwardsville
Prices starting at $567 for return flights and $144 for one-way flights to Edwardsville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Edwardsville economy flight packages
The Wildwood Hotel
May 11 - May 15
Knoxville (TYS) to St. Louis (STL)
Reviewed on Oct 16, 2025
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
May 11 - May 15
Knoxville (TYS) to St. Louis (STL)
Reviewed on Apr 20, 2022
More About Flying To Edwardsville from Knoxville
Route Information for Flights from Knoxville to Edwardsville
Origin Airport IATA Code | TYS |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Knoxville to Edwardsville
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.