$158 Cheap flight deals from Panama City (PTY) to Guatemala City (GUA)

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This Weekend's Flight Deals from Panama City to Guatemala City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 22 - Sun, May 24
PTY
Tocumen Intl.
GUA
La Aurora Intl.
$346 Roundtrip, just found
$346
Roundtrip
just found
Select avianca flight, departing Fri, May 22 from Tocumen Intl. to La Aurora Intl., returning Sun, May 24, priced at $346 just found

Airfares from $158 One Way, $295 Round Trip from Panama City to Guatemala City

Prices starting at $295 for return flights and $158 for one-way flights to Guatemala City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jul 6 - Sat, Jul 11
PTY
Panama City
GUA
Guatemala City
$295 Roundtrip, found 1 day ago
$295
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jul 6 from Panama City to Guatemala City, returning Sat, Jul 11, priced at $295 found 1 day ago
Mon, Jul 6 - Sat, Jul 11
PTY
Panama City
GUA
Guatemala City
$303 Roundtrip, found 1 day ago
$303
Roundtrip
found 1 day ago
Select Copa flight, departing Mon, Jul 6 from Panama City to Guatemala City, returning Sat, Jul 11, priced at $303 found 1 day ago
Wed, Jun 3 - Thu, Jun 4
PTY
Panama City
GUA
Guatemala City
$303 Roundtrip, found 2 days ago
$303
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Jun 3 from Panama City to Guatemala City, returning Thu, Jun 4, priced at $303 found 2 days ago
Wed, Jun 3 - Thu, Jun 4
PTY
Panama City
GUA
Guatemala City
$311 Roundtrip, found 2 days ago
$311
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Jun 3 from Panama City to Guatemala City, returning Thu, Jun 4, priced at $311 found 2 days ago
Wed, Jun 3 - Thu, Jun 4
PTY
Panama City
GUA
Guatemala City
$318 Roundtrip, found 2 days ago
$318
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Jun 3 from Panama City to Guatemala City, returning Thu, Jun 4, priced at $318 found 2 days ago

Guatemala City economy flight packages

Price found within the past 48 hours. Click for updated prices.
El Carmen Hotel
3.0-star property

El Carmen Hotel

9/10 Wonderful! (791 reviews)

Jun 25 - Jun 28

3 night stay

Panama City (PTY) to Guatemala City (GUA)

Copa • Roundtrip • Coach
Price was $688, price is now $496 per person
$496
per person
found 1 day ago
Excellent stay! Very clean, food was amazing, sheets and towels were very comfortable. Overall great experiences, even enjoyed a massage!

Reviewed on Feb 4, 2026

Hotel Soleil La Antigua
4.0-star property

Hotel Soleil La Antigua

8.6/10 Excellent! (1,003 reviews)

Jun 25 - Jun 28

3 night stay

Panama City (PTY) to Guatemala City (GUA)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $889, price is now $529 per person
$529
per person
found 1 day ago
Everything was fine, nice and clean room,easy parking

Reviewed on Sep 28, 2025

Casa Faustina Boutique Hotel
4.0-star property

Casa Faustina Boutique Hotel

8.8/10 Excellent! (114 reviews)

Jun 25 - Jun 28

3 night stay

Panama City (PTY) to Guatemala City (GUA)

Copa • Roundtrip • Coach
Price was $798, price is now $573 per person
$573
per person
found 1 day ago
Friendly and courteous staff and great accommodations.

Reviewed on Jan 21, 2024

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More About Flying To Guatemala City from Panama City

Route Information for Flights from Panama City to Guatemala City

Origin Airport IATA Code
PTY
Destination Airport IATA Code
GUA
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Guatemala City

Those who want guaranteed low prices for Panama City to Guatemala City flights only need to visit Orbitz. We take advantage of the latest mobile technologies to make sure you get the best bargain on your trip and that everything goes smoothly and according to your plans.

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Combine Car Rental With Your Discount Flight For Even More Savings

Not only can we get bargain deals on flights from Panama City to Guatemala City but we can book your transport as well. By combining car rental with Panama City to Guatemala City flights, you can be sure to save money and start moving as soon as you hit the ground.

Use Orbitz On The Go To Stay Informed Using Your Smartphone

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Frequently asked questions

Are there non-stop flights from Panama City to Guatemala City?
Get your passport ready, because Copa Airlines will take you straight from Panama City to Guatemala City. Book your fare now and enjoy a relaxing, nonstop flight.
What is the shortest flight from Panama City to Guatemala City?
With the trip from PTY to Guatemala City (GUA-La Aurora Intl.) taking a minimum of 3 hours and 1 minute, there's plenty of time to sit back and enjoy the ride. Treat yourself to an in-flight vino and get cozy in your seat with a gripping book or movie.
What airlines fly from Panama City to Guatemala City most frequently?
Book your Panama City to Guatemala City journey with a Copa Airlines flight. With 82 each month, this airline offers the most flights between these two destinations.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.