$166 Cheap flight deals from Panama City (PTY) to Guayaquil (GYE)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Panama City to Guayaquil

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 3 - Sat, Jan 10
PTY
Tocumen Intl.
GYE
Jose Joaquin de Olmedo Intl.
$537 Roundtrip, found 1 day ago
$537
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Jan 3 from Tocumen Intl. to Jose Joaquin de Olmedo Intl., returning Sat, Jan 10, priced at $537 found 1 day ago

Airfares from $166 One Way, $367 Round Trip from Panama City to Guayaquil

Prices starting at $367 for return flights and $166 for one-way flights to Guayaquil were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jan 15 - Sun, Jan 18
PTY
Panama City
GYE
Guayaquil
$367 Roundtrip, found 23 hours ago
$367
Roundtrip
found 23 hours ago
Select avianca flight, departing Thu, Jan 15 from Panama City to Guayaquil, returning Sun, Jan 18, priced at $367 found 23 hours ago
Thu, Jan 15 - Sun, Jan 18
PTY
Panama City
GYE
Guayaquil
$424 Roundtrip, found 23 hours ago
$424
Roundtrip
found 23 hours ago
Select avianca flight, departing Thu, Jan 15 from Panama City to Guayaquil, returning Sun, Jan 18, priced at $424 found 23 hours ago
Sun, Jan 11 - Thu, Jan 15
PTY
Panama City
GYE
Guayaquil
$426 Roundtrip, found 1 day ago
$426
Roundtrip
found 1 day ago
Select avianca flight, departing Sun, Jan 11 from Panama City to Guayaquil, returning Thu, Jan 15, priced at $426 found 1 day ago
Wed, Dec 31 - Mon, Jan 19
PTY
Panama City
GYE
Guayaquil
$434 Roundtrip, found 4 days ago
$434
Roundtrip
found 4 days ago
Select avianca flight, departing Wed, Dec 31 from Panama City to Guayaquil, returning Mon, Jan 19, priced at $434 found 4 days ago
Mon, Jan 26 - Mon, Feb 2
PTY
Panama City
GYE
Guayaquil
$463 Roundtrip, found 1 day ago
$463
Roundtrip
found 1 day ago
Select avianca flight, departing Mon, Jan 26 from Panama City to Guayaquil, returning Mon, Feb 2, priced at $463 found 1 day ago

More About Flying To Guayaquil from Panama City

Route Information for Flights from Panama City to Guayaquil

Origin Airport IATA Code
PTY
Destination Airport IATA Code
GYE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Panama City to Guayaquil

Score low fares on flights from Panama City to Guayaquil with Orbitz. We make it easier than ever to find cheap Panama City to Guayaquil flights with our cutting-edge mobile tools and mobile website.

Book Discount Flights From Panama City to Guayaquil in Minutes

If you are looking for low cost Panama City to Guayaquil flights, just skip all of the other so-called bargain travel sites, because Orbitz offers guaranteed low fares. That means you don't have to constantly scan multiple sites and hover like a vulture at your computer, hoping to score better deals through last-minute sales.

Find Bargain Panama City to Guayaquil Flights With Our Convenient Tools

You benefit from more than just cheap flights from Panama City to Guayaquil. Orbitz is a convenient one-stop trip planner. Research weather, attractions, and transportation options for Guayaquil to help you plan your trip and decide what to pack and where to go.

Booking domestic or international air fare and accommodations with Orbitz is a snap. Use your iPad, iPhone or Android device to find discount flights from Panama City to Guayaquil even while on the move, and sign up for instant email and text alerts to stay up-to-date on any delays affecting your flight. Or access m.orbitz.com via your mobile device’s Web browser.

Earn Miles through Orbitz for Your Frequent Flyer Program

You don't have to give up frequent flyer points to take advantage of our low fares. Add your frequent flyer number when you book your Panama City to Guayaquil flights to receive credit for your trip.

Frequently asked questions

Are there non-stop flights from Panama City to Guayaquil?
Get your passport ready, because Copa Airlines will take you straight from Panama City to Guayaquil. Book your ticket now and enjoy a stress-free, nonstop flight.
What is the shortest flight from Panama City to Guayaquil?
It can be as a short and sweet as 2 hours and 11 minutes. If you're of the opinion that your vacation hours should be spent 'vacationing' rather than flying, you'll enjoy the flight from Panama City to Guayaquil.
What airlines fly from Panama City to Guayaquil most frequently?
Copa Airlines is the most frequent flyer along this route. This top-rated airline operates 152 flights from PTY to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.