$75 Cheap flight deals from Mayagüez (SJU) to Santo Domingo (SDQ)
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This Weekend's Flight Deals from Mayagüez to Santo Domingo
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $75 One Way, $159 Round Trip from Mayagüez to Santo Domingo
Prices starting at $159 for return flights and $75 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santo Domingo economy flight packages
Coral Costa Caribe Beach Resort - All Inclusive
Sep 26 - Sep 28
San Juan (SJU) to Santo Domingo (SDQ)
Santo Domingo (SDQ) to San Juan (SJU)
Reviewed on Jun 28, 2025
Sybaris Residences
Sep 4 - Sep 7
San Juan (SJU) to Santo Domingo (SDQ)
Santo Domingo (SDQ) to San Juan (SJU)
Reviewed on Dec 17, 2018
Santo Domingo business class flight packages
Sybaris Residences
Sep 6 - Sep 7
San Juan (SJU) to Santo Domingo (SDQ)
Reviewed on Dec 17, 2018
More About Flying To Santo Domingo from Mayagüez
Route Information for Flights from Mayagüez to Santo Domingo
Origin Airport IATA Code | SJU |
|---|---|
Destination Airport IATA Code | SDQ |
Distance | 240 mi |
Direct Flight Airlines | Frontier Airlines, JetBlue |
Earliest Flight Arrival | 11:51AM UTC |
Latest Flight Arrival | 12:45AM UTC |
Mayagüez to Santo Domingo
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Cruising for a bargain deal
Regardless of your destination, we always provide you fantastic bargains for your trip, and that includes on hotels and even cruises. We offer budget air fares on flights from Mayagüez to Santo Domingo so you can reach your destination with more money in your pocket to spend.
Cheap Mayagüez to Santo Domingo flights that lead to rewards
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Quality combinations
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Even last minute bookings on our apps
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Frequently asked questions
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Santo Domingo Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.