Southwest Ohio Vacation Homes

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Featured Vacation Homes in Southwest Ohio

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Southwest Ohio

    Hilton Cincinnati Netherland Plaza

    Hilton Cincinnati Netherland Plaza

    35 W 5th St Cincinnati OH
    $115 nightly
    The price is $137 total per night from Jan 1 to Jan 2
    $137 total
    Jan 1 - Jan 2, 2026
    Total with taxes and fees
    7.8/10 Good! (1,319 reviews)
    Radisson Hotel Cincinnati Riverfront

    Radisson Hotel Cincinnati Riverfront

    668 W 5th St Covington KY
    $76 nightly
    The price is $85 total per night from Dec 29 to Dec 30
    $85 total
    Dec 29 - Dec 30
    Total with taxes and fees
    7.2/10 Good! (2,422 reviews)
    voco The Clair Cincinnati Downtown by IHG

    voco The Clair Cincinnati Downtown by IHG

    701 Broadway Street Cincinnati OH
    $122 nightly
    The price is $146 total per night from Jan 20 to Jan 21
    $146 total
    Jan 20 - Jan 21, 2026
    Total with taxes and fees
    9/10 Wonderful! (1,003 reviews)

Southwest Ohio Vacation Homes

Book vacation homes in Southwest Ohio
Next time you take a group getaway top Southwest Ohio, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Southwest Ohio vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Southwest Ohio vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Southwest Ohio; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Southwest Ohio rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Southwest Ohio is sure to be a winner.

Southwest Ohio Vacation Homes essential information

Accommodation
791 Vacation Homes
Lowest Price
$85
Highest Price
$331
Popular accommodation
Casa Clifton Guest Lodge, Queen City Family House - 5BR/Backyard/Home Theater/Kid Friendly, Suite Springs, Boho Bungalow: 3BR on Miami Bike Path, Sleeps 7!, Tres House - an experience, three floors high., Modern Farmhouse in Ross Township, Cheerful 3-bedroom house Sleep 11, Centrally located Modern entertainment home for the whole family , Stylish Retreat: Hot Tub, Spa, Arcade, Pinball WPAFB Museum

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