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Featured Southern Indiana Boutique Hotels

21c Museum Hotel Louisville
700 W Main Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$165 nightly
The price is $195 total per night
$195 total
Nov 20 - Nov 21
Total with taxes and fees
Guests staying at 21c Museum Hotel Louisville enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night, and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, tours or tickets, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include meeting rooms, conference space, and a 24-hour business center.
Spa
Pet friendly

Market Street Inn
330 West Market Street, Jeffersonville, IN
$167 nightly
The price is $188 total per night
$188 total
Nov 9 - Nov 10
Total with taxes and fees
At Market Street Inn, guests have access to a rooftop terrace, free WiFi in public areas, and a terrace. Free parking is included with your stay. Front-desk staff can assist with concierge services and luggage storage. Other amenities at this boutique bed & breakfast include a fireplace in the lobby, a picnic area, and a gift shop.
Breakfast included
Parking included

The Brown Hotel
335 W Broadway, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$168 nightly
The price is $198 total per night
$198 total
Nov 23 - Nov 24
Total with taxes and fees
The Brown Hotel features a gym, free WiFi in public areas, and meeting rooms. Parking is USD 30 per night (USD 36 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle (available 24 hours). Multilingual staff at the front desk are standing by 24/7 to help with concierge services, luggage storage, and securing valuables. Other amenities at this luxury hotel include conference space, a 24-hour business center, and free newspapers.
Free airport shuttle
Free WiFi

Embassy Suites Louisville Downtown
501 South Fourth Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$122 nightly
The price is $144 total per night
$144 total
Nov 17 - Nov 18
Total with taxes and fees
At Embassy Suites Louisville Downtown, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 45 per night. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and tours or tickets. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$133 nightly
The price is $157 total per night
$157 total
Nov 25 - Nov 26
Total with taxes and fees
Guests staying at Galt House Hotel Trademark Collection by Wyndham enjoy access to a full-service spa, a gym, and free WiFi in public areas. Valet parking is available for USD 55 per night. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include conference space, a 24-hour business center, and a seasonal outdoor pool.
Pool
Spa
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southern Indiana hotels essential information
Accommodation | 1,568 hotels |
|---|---|
Lowest Price | $144 |
Highest Price | $198 |
Popular hotels | 21c Museum Hotel Louisville, Market Street Inn, The Brown Hotel, Embassy Suites Louisville Downtown, Galt House Hotel Trademark Collection by Wyndham |
Recent Boutique Hotels Reviews

Bally’s Evansville Casino & Hotel
5/5 Excellent
"room was great, fromt desk staff was super helpful & friendly"
A verified traveler from Evansville stayed at Bally’s Evansville Casino & Hotel
Posted 2 days ago
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