Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast

Choose dates to view prices

Where to?

Dates

September 2025

October 2025

Premium bedding, down comforters, pillowtop beds, in-room safe

Indoor pool, open 8 AM to 11 PM, sun loungers

Overview
Rooms
Location
Policies

Exceptional

Popular amenities

Laundry
Housekeeping

Explore the area

3253 William Street, Cape Girardeau, MO, 63701

Place, Saint Francis Medical Center
‪6 min walk‬
Place, Southeast Missouri State University
‪6 min drive‬
Place, Isle Casino Cape Girardeau
‪8 min drive‬
Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
‪7 min drive‬

Room options

Suite, 1 King Bed

Exceptional

Sleeps 2
1 King Bed

Standard Room, 1 Queen Bed

Wonderful

400 sq ft
Sleeps 2
1 Queen Bed

Suite, 2 Queen Beds, Accessible (Mobility)

Exceptional

400 sq ft
Sleeps 6
2 Queen Beds

Suite, 2 Queen Beds

Exceptional

Sleeps 6
2 Queen Beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

Exceptional

Sleeps 2
1 King Bed

Standard Room

Very good

400 sq ft
Sleeps 2
1 King Bed

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Very good

400 sq ft
Sleeps 6
2 Queen Beds

Suite, 1 King Bed, Accessible (Mobility)

Exceptional

Sleeps 2
1 King Bed

Suite, 1 Bedroom (Feature)

Exceptional

Sleeps 2
1 Queen Bed

About the neighborhood

Cape Girardeau

Located within a leisurely stroll of Saint Francis Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is within a few miles (5 km) of Saint Francis Healthcare System. This hotel has 102 rooms and welcomes guests with conveniences like free breakfast, a full-service spa, and an indoor pool.

What's nearby

Saint Francis Medical Center - 6 min walk - 0.4 miles
Southeast Missouri State University - 6 min drive - 3.7 miles
Riverfront Bridge Park - 7 min drive - 4.0 miles
Show Me Center - 7 min drive - 4.4 miles
Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

‪Chick-fil-A - ‬7 min walk
‪Rhodes - ‬20 min walk
‪McDonald's - ‬10 min walk
‪Chili's Grill & Bar - ‬4 min walk
‪White Castle - ‬10 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.

52-inch flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries, and pillowtop beds with premium bedding and pillow menus ensure a restful night. Other amenities include sitting areas, microwaves, and coffee makers.

Recreational amenities at the hotel include an indoor pool and a fitness center.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Pool
Hot Tub
Breakfast included
Pet friendly

$90 nightly

Oct 5 - Oct 6

Total with taxes and fees

Property amenities

Internet

Available in all rooms: Free WiFi and wired internet
Available in some public areas: Free WiFi and wired internet

Parking and transportation

Free self parking on site
Wheelchair-accessible parking available

Food and drink

Free breakfast available

Things to do

Full-service spa
Gym
Indoor pool

Family friendly

In-room microwave
Indoor pool
Laundry facilities
Mini-fridge

Conveniences

24-hour front desk
Free newspapers in lobby
Laundry facilities
Luggage storage
Safe at front desk
Vending machine

Guest services

Dry cleaning/laundry service
Housekeeping (daily)
Porter/bellhop

Business services

118 square feet of conference space
Business center
Meeting room

Outdoors

Pool loungers

Accessibility

If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Assistive listening devices
Braille/raised signage
Visual fire alarm
Well-lit path to entrance
Wheelchair accessible (may have limitations)
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to elevator

1 building
4 floors
Banquet hall
Smoking not allowed

Room amenities

Bedroom

Down comforter
Pillow menu
Pillowtop mattress
Premium bedding

Bathroom

Free toiletries
Hair dryer
Private bathroom
Shampoo
Soap
Toilet paper
Towels provided

Entertainment

52-inch flat-screen TV with premium cable channels

Food and drink

Coffee/tea maker
Microwave
Mini-fridge

Air conditioning (climate-controlled)
Connecting rooms available
Desk
Free local calls
Iron/ironing board
Laptop workspace
Phone
Safe
Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime

Contactless check-in available

Minimum check-in age: 21

Check-out

Check-out before 11 AM

Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

This property doesn't allow pets

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Cashless transactions are available

Safety features at this property include a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

Check-in: 3:00 PM—-anytime
Check-out: 11 AM
Minimum check-in age: 21

The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Charges for extra guests may apply and vary depending on the property's policy.
A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
This property accepts credit cards. Cash is not accepted.
Onsite safety features include a smoke detector.
Cashless payment methods are available for all transactions.
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

Pool access available from 8 AM to 11 PM.
Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
No cribs or infant beds are available.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55

Holiday Inn Express Hotel Cape Girardeau I-55

Holiday Inn Hotel I-55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Inn Express Cape Girarau I55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG provides free cancellation on some room rates. For more details, review the cancellation policy on our site.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Sep 29, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Oct 19, 2025 start from $95.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to see close to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel is located in Cape Girardeau, close to Show Me Center, Riverfront Bridge Park, and Isle Casino Cape Girardeau. You'll also find Shawnee National Forest and Mississippi River within a short drive.

Is parking available on site at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Is there a spa available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

There is a full-service spa at this available for guests to enjoy at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG include a casino at the property?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 11 PM.

Is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG good for couples?

Couples staying at this hotel will appreciate amenities like a pillowtop mattress and free Internet access as well as an indoor pool.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a hot tub?

No, there isn't a spa tub at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a restaurant that serves breakfast?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast though there is no restaurant.

Will Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Are there connecting rooms at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

How close is the airport from Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

The closest major airport to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 6.1 mi away (10 minutes by car). Another top airport is Cairo, IL (CIR-Cairo Regional), which is around 25.5 mi away.

Are there rooms with balconies at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, you won't find guestrooms with balconies at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

Aug 1, 2025

Liked: Cleanliness

Disliked: Staff & service

My first experience upon walking in the door was Katy - GM who definitely let it be known that she hated her job without saying "I hate my job". Critical, rude, and talking down to me is NOT a way to give me a great first impression. She barked commands at me and ridiculed me infront of other customers for not knowing my license plate. News flash - my state changed their plates and assigned it to me 3 weeks ago. I'm more than sure there were no other vehicles from my state in your Missouri parking lot. Being told I needed to walk outside in the 103° heat index was ridiculous. The room was 78° when we entered - horribly stuffy. I did not feel like I could call the front desk for anything after being treated so badly when I checked in. Breakfast was lukewarm - not up to temp. Just kind of blah...

Stayed 1 night in Jul 2025

10/10 Excellent

Letha, Madison

Jun 30, 2025

Stayed 1 night in Apr 2025

10/10 Excellent

Lucas

Traveled with family and small children

Jun 22, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Excellent experience for our family. Every member of the staff we encountered were great. Breakfast was good, room was clean and spacious. Above and beyond expectations, would absolutely stay here again!

Stayed 2 nights in Jun 2025

10/10 Excellent

10/10 Excellent

Lana

Traveled with family

Jun 9, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay

It was wonderful. Pool and workout room was in great shape and centrally located. Breakfast was amazing and night time cookies and milk was a nice surprise that my daughter didn’t let me forget. The staff was all super nice and I’d definitely stay again if in the area.