Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast

Choose dates to view prices

Where to?

Dates

August 2025

September 2025

Relax in the stylish lobby, featuring a fireplace, comfortable seating, and a large flat-screen TV.

Indulge in a diverse selection of international cuisine at our hotel's buffet.

Relax in this stylish room with a comfortable seating area, wooden staircase, and modern decor.

Relax by the pool surrounded by comfortable lounge chairs and tables.

Comfortable room with a large bed, desk, and television, offering a peaceful retreat.

Overview
Rooms
Location
Policies

Popular amenities

Laundry
Housekeeping

Explore the area

3253 William Street, Cape Girardeau, MO, 63701

Saint Francis Medical Center
‪6 min walk‬
Southeast Missouri State University
‪6 min drive‬
Isle Casino Cape Girardeau
‪8 min drive‬
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
‪7 min drive‬

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Room options

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed

Exceptional

Sleeps 2
1 King Bed

Standard Room, 1 Queen Bed

Wonderful

400 sq ft
Sleeps 2
1 Queen Bed

Suite, 2 Queen Beds, Accessible (Mobility)

Exceptional

400 sq ft
Sleeps 6
2 Queen Beds

Suite, 2 Queen Beds

Exceptional

Sleeps 6
2 Queen Beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

Exceptional

Sleeps 2
1 King Bed

Standard Room

Very good

400 sq ft
Sleeps 2
1 King Bed

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Very good

400 sq ft
Sleeps 6
2 Queen Beds

Suite, 1 King Bed, Accessible (Mobility)

Exceptional

Sleeps 2
1 King Bed

Suite, 1 Bedroom (Feature)

Exceptional

Sleeps 2
1 Queen Bed

About the neighborhood

Cape Girardeau

Located within a leisurely stroll of Saint Francis Medical Center, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is within a few miles (5 km) of Saint Francis Healthcare System. This hotel has 102 rooms and welcomes guests with conveniences like free breakfast, a full-service spa, and an indoor pool.

What's nearby

Saint Francis Medical Center - 6 min walk - 0.4 miles
Southeast Missouri State University - 6 min drive - 3.5 miles
Riverfront Bridge Park - 7 min drive - 4.0 miles
Show Me Center - 8 min drive - 4.1 miles
Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

‪Chick-fil-A - ‬6 min walk
‪McDonald's - ‬10 min walk
‪Panera Bread - ‬2 min walk
‪Texas Roadhouse - ‬5 min walk
‪O'Charley's Restaurant + Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with a full-service spa and free breakfast

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.

52-inch flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms offer hair dryers and free toiletries, and pillowtop beds with premium bedding and pillow menus ensure a restful night. Other amenities include sitting areas, microwaves, and coffee makers.

Recreational amenities at the hotel include an indoor pool and a fitness center.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Languages

English

Similar properties

Relax in a stylish lounge area with a curved sofa, coffee table, and large flat-screen TV.

Pool
Hot Tub
Breakfast included
Pet friendly

$102 nightly

Aug 10 - Aug 11

Total includes taxes and fees

Property amenities

Internet

Available in all rooms: Free WiFi and wired internet
Available in some public areas: Free WiFi and wired internet

Parking and transportation

Free self parking on site
Wheelchair-accessible parking available

Food and drink

Free breakfast available

Things to do

Full-service spa
Gym
Indoor pool

Family friendly

In-room microwave
Indoor pool
Laundry facilities
Mini-fridge

Conveniences

24-hour front desk
Free newspapers in lobby
Laundry facilities
Luggage storage
Safe at front desk
Vending machine

Guest services

Dry cleaning/laundry service
Housekeeping (daily)
Porter/bellhop

Business services

118 square feet of conference space
Business center
Meeting room

Outdoors

Pool loungers

Accessibility

If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Assistive listening devices
Braille/raised signage
Visual fire alarm
Well-lit path to entrance
Wheelchair accessible (may have limitations)
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to elevator

1 building
4 floors
Banquet hall
Smoking not allowed

Room amenities

Bedroom

Down comforter
Pillow menu
Pillowtop mattress
Premium bedding

Bathroom

Free toiletries
Hair dryer
Private bathroom
Shampoo
Soap
Toilet paper
Towels provided

Entertainment

52-inch flat-screen TV with premium cable channels

Food and drink

Coffee/tea maker
Microwave
Mini-fridge

Air conditioning (climate-controlled)
Connecting rooms available
Desk
Free local calls
Iron/ironing board
Laptop workspace
Phone
Safe
Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime

Contactless check-in available

Minimum check-in age: 21

Check-out

Check-out before 11 AM

Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

This property doesn't allow pets

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Cashless transactions are available

Safety features at this property include a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

Check-in: 3:00 PM—-anytime
Check-out: 11 AM
Minimum check-in age: 21

The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Charges for extra guests may apply and vary depending on the property's policy.
A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
This property accepts credit cards. Cash is not accepted.
Onsite safety features include a smoke detector.
Cashless payment methods are available for all transactions.
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

Pool access available from 8 AM to 11 PM.
Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
No cribs or infant beds are available.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55

Holiday Inn Express Hotel Cape Girardeau I-55

Holiday Inn Hotel I-55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Inn Express Cape Girarau I55

Holiday Inn Express Hotel Suites Cape Girardeau I 55

Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG provides free cancellation on some room rates. For more details, review the cancellation policy on our site.

What's there to see close to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel is located in Cape Girardeau, close to Show Me Center, Riverfront Bridge Park, and Isle Casino Cape Girardeau. You'll also find Shawnee National Forest and Mississippi River within a short drive.

Will I be able to park at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Is there a spa available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

There is a full-service spa at this available for guests to enjoy at this hotel.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG include a casino at the property?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 11 PM.

What do couples enjoy most about Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Couples staying at this hotel will appreciate amenities like a pillowtop mattress and free Internet access as well as an indoor pool.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a hot tub?

No, this hotel doesn't have a spa tub.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a restaurant that serves breakfast?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast though there is no restaurant.

Will Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have connecting rooms?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

How close is the airport from Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

The closest major airport to Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 6.1 mi away (10 minutes by car). Another top airport is Cairo, IL (CIR-Cairo Regional), which is around 25.5 mi away.

Are there rooms with balconies that I can book at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, there aren't any guestrooms that list a balcony.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

4/10 Poor

Morag

Aug 1, 2025

Liked: Cleanliness

Disliked: Staff & service

My first experience upon walking in the door was Katy - GM who definitely let it be known that she hated her job without saying "I hate my job". Critical, rude, and talking down to me is NOT a way to give me a great first impression. She barked commands at me and ridiculed me infront of other customers for not knowing my license plate. News flash - my state changed their plates and assigned it to me 3 weeks ago. I'm more than sure there were no other vehicles from my state in your Missouri parking lot. Being told I needed to walk outside in the 103° heat index was ridiculous. The room was 78° when we entered - horribly stuffy. I did not feel like I could call the front desk for anything after being treated so badly when I checked in. Breakfast was lukewarm - not up to temp. Just kind of blah...

Stayed 1 night in Jul 2025

10/10 Excellent

Gunnar

May 4, 2025

Stayed 2 nights in Apr 2025

8/10 Good

Dawn

May 2, 2025

Stayed 2 nights in Apr 2025

10/10 Excellent

Darci

Apr 28, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stayed 1 night in Apr 2025

8/10 Good

Jose

Apr 25, 2025

Stayed 1 night in Apr 2025

10/10 Excellent

Xenia

Business traveler

Apr 25, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Return Stay💋

I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return.

Stayed 1 night in Apr 2025

10/10 Excellent

Nick

Traveled with group

Apr 24, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Front desk was super helpful at check in and very courteous throughout the whole stay

Stayed 2 nights in Apr 2025

10/10 Excellent

Lindsey

Traveled with family and small children

Apr 24, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Check-in was seamless. Staff was kind. They had fresh cookies at 8 p.m. which the kids loved. The pool area is very well maintained and nice. Fitness area looked very nice right through the pool area. Rooms are clean, decent and in good repair, and the hotel is quiet. Could not be happier with the value of this stay for my family. We have Panera, Starbucks, Chik-fil-a, Texas Roadhouse, Cracker Barrel and more right around our hotel. There is a shopping center nearby with a TJmaxx and some other stores. Overall a really great stop that we will remember when we take this route for future drives. Thank you, Holiday Inn Express!

Stayed 1 night in Apr 2025

10/10 Excellent

Theresa, Battle Creek

Apr 22, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Stayed 1 night in Apr 2025

2/10 Terrible

William

Traveled with family

Apr 21, 2025

Liked: Room comfort

Disliked: Staff & service, property conditions & facilities

Bad place to stay

It was not a very good place for the money you pay the floor was squeaky upstairs so i heard that most of the night and also sounded like a heard of cattle running across the floor

Stayed 1 night in Apr 2025

10/10 Excellent

Verified traveler

Traveled with family

Apr 19, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Super Cute

This hotel was super cute and the staff was quite friendly. Our room had a window overlooking the pool so that was pretty neat. Breakfast was also nice.

Stayed 1 night in Apr 2025

10/10 Excellent

Constance, Washington

Apr 9, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Will definitely stay there again!!

Stayed 1 night in Apr 2025

10/10 Excellent

Joan

Apr 8, 2025

Liked: Cleanliness, amenities

Excellent Hotel. Good breakfast. Great room. We will stay again if we are in the area

Stayed 1 night in Mar 2025

10/10 Excellent

rick

Traveled with family

Apr 8, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stayed 2 nights in Mar 2025

10/10 Excellent

Sarah

Apr 7, 2025

Liked: Cleanliness, staff & service, property conditions & facilities

Stayed 2 nights in Apr 2025

8/10 Good

Michael

Apr 6, 2025

Stayed 1 night in Apr 2025

10/10 Excellent

Scott

Apr 5, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stayed 1 night in Apr 2025

10/10 Excellent

Brian

Traveled with family and small children

Mar 29, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

We enjoyed our stay both times on our vacation to New Orleans.

Stayed 1 night in Mar 2025

8/10 Good

Ashley

Traveled with family and small children

Mar 29, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Great location. Clean

Stayed 2 nights in Mar 2025

10/10 Excellent

Tamara

Traveled with family

Mar 27, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stayed 1 night in Mar 2025

10/10 Excellent

Thea

Traveled with family

Mar 27, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

This was a nice hotel to spend the night on a long road trip. We did not use the pool as it was completely full of kids who did not see to be supervised well by their parents, which is not the hotel's fault.

Stayed 1 night in Mar 2025

10/10 Excellent

meagan

Mar 24, 2025

Stayed 1 night in Mar 2025

10/10 Excellent

Robin

Traveled with partner

Mar 24, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

This hotel was clan and the staff was friendly. The workout room and the pool were small but clean. The staff were friendly.

Stayed 3 nights in Mar 2025

10/10 Excellent

Shannon

Business traveler

Mar 23, 2025

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

I'll be back!!

Needed an overnight traveling back home. Nabbed this great room. Just wish that I would have been there a bit lo ger to enjoy it. Super hot shower with great water pressure was also very welcome. The macadamia nut cookies were awesome!!

Stayed 1 night in Mar 2025

10/10 Excellent

Kyle

Traveled with family and small children, Traveled with family

Mar 22, 2025

Liked: Cleanliness, staff & service, amenities, property conditions & facilities

Very clean, great location especially while traveling (gas stations/stores/restaurants) parking was also very convenient. The breakfast in the morning was free with many options. Dining area was also clean and I saw staff cleaning just about everywhere on every surface on our way to check out. Would stay again.

Stayed 1 night in Mar 2025