$22 Cheap flights to Southern Region
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Cheap flights to Southern Region from $22 One Way, $38 Round Trip
$38 return flights and $22 one-way flights to Southern Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
Find The Perfect Hotel For After Your Flight
Score Epic Southern Region Accommodation Deals
Corinthia St George's Bay
"Beautiful hotel right on the bay. Plenty of options for food and drink, gorgeous pools and lounging areas and a great spa"
Reviewed on Sep 24, 2026
The Westin Dragonara Resort, Malta
"Great hotel. Brilliant breakfast spread, friendly and helpful staff, gym is top tier and 2 x outside pools + 1 inside. We had a very pleasant stay."
Reviewed on Sep 24, 2026
Hyatt Regency Malta
"Lovely experience. Great room and wonderful staff"
Reviewed on Sep 22, 2026
Azur Hotel by ST Hotels
"Super nice front-desk staff, this is very important as it is always the first impression you have of the hotel. Check-in and out was very easy and seamless. Not sure if the hotel is old or just not very well maintained, but my room smelled very strongly of a musty odor which did not air out or disappear ..."
Reviewed on Sep 20, 2026
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Southern Region
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First-Timers
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Ports and Play
Be sure to check our cruise page for free shore excursions, onboard spending, balcony upgrades and other perks. Orbitz offers last-minute, luxury, weekend and summer cruises. You can even designate which port you want to sail from and pre-book on-shore activities. Get there on the cheap with discounts on flights to Southern Region and Southern Region flights. Get more bang for your travel buck at Orbitz.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.