$129 Cheap flights to Distrito Colón

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Top places to visit in Distrito Colón

Cheap flights to Distrito Colón from $129 One Way, $264 Round Trip

$264 return flights and $129 one-way flights to Distrito Colón were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
SJOTocumenJune 21 to June 24$264
FLLTocumenJune 20 to July 1$568
MIATocumenJune 20 to June 24$626
CCSTocumenJune 21 to June 24$692
JFKTocumenJune 20 to June 25$714
JFKTocumenJune 20 to June 25$714
MEXTocumenJune 20 to June 21$755
FCOTocumenJune 21 to July 1$937
LAXTocumenJune 21 to June 28$984
ATLTocumenJune 20 to June 26$1,010
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Distrito Colón Accommodation Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $137 total per night from Jun 29 to Jun 30
$137 total
Jun 29 - Jun 30
Total with taxes and fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (5,603 reviews)
"Amazing breakfast. Uncomfortable bed. Very stiff. Super thick high pillows. Also only a single sheet on bed, no blanket. Bed situation very unfortunate. Breakfast salvaged it but that’s not why you sleep somewhere"

Reviewed on Jun 18, 2026

Opens in a new windowHotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$137 nightly
The price is $151 total per night from Jul 4 to Jul 5
$151 total
Jul 4 - Jul 5
Total with taxes and fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,616 reviews)
"When you walk in it smells very nice, very clean. The staff provide good services, very friendly, The rooms are very elegant, and clean, the utilities are great. They provide transportation from the airport. Delicious breakfast, fresh lemon water to drink. With a area for your business needs. The ..."

Reviewed on Jun 17, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $139 total per night from Jul 4 to Jul 5
$139 total
Jul 4 - Jul 5
Total with taxes and fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,000 reviews)
"Everything is great"

Reviewed on Jun 9, 2026

Opens in a new windowSheraton Grand Panama
Save an average of 15% on thousands of hotels when you're signed in
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $299 total per night from Jun 19 to Jun 20
$299 total
Jun 19 - Jun 20
Total with taxes and fees
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.6/10 Good! (1,006 reviews)
"Everyone was very friendly and courteous. Property was clean and the entire trip was just excellent. Love Panama and absolutely love the staff at Dreams Playa Bonita. Felt like home."

Reviewed on Jun 16, 2026

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Distrito Colón

Are you in the mood for a cruise? Shop Orbitz today for cheap cruises and flights to Distrito Colón. Our award-winning cruise site features exclusive offers, information for first-timers and top destinations and activities. Make discount domestic and international travel plans in an instant with cutting-edge mobile tools from Orbitz.

Top Pick

Orbitz holds a “Best of the Web” Cruise Site Award from Forbes Magazine. You won’t find better deals anywhere on low cost cruises and low fare Distrito Colón flights. Our Customer Care and guaranteed low prices make Orbitz the team to beat in budget cruises and air ticket sales.

Exclusive Offers

Register for Orbitz email updates and our cruise experts will notify you of bargain tickets on cruises as they’re posted. Install our free mobile apps on your iPad, iPhone or Android for easy booking and mobile-only savings on flights to Distrito Colón. Visit www.Orbitz.com to learn more about these amazing benefits and our 110% Best Price Guarantee.

First-Timers

Are you and your family cruise newbies? Orbitz offers Cruising 101 and Cruise FAQ to answer any questions you may have. Book your cruise and air travel with Orbitz On the Go for greater savings on Distrito Colón flights.

Ports and Play

Be sure to check our cruise page for free shore excursions, onboard spending, balcony upgrades and other perks. Orbitz offers last-minute, luxury, weekend and summer cruises. You can even designate which port you want to sail from and pre-book on-shore activities. Get there on the cheap with discounts on flights to Distrito Colón and Distrito Colón flights. Get more bang for your travel buck at Orbitz.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.