Book 4 Star Hotels in Southeast Iowa

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Dec 27 - Dec 28
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Dec 28 - Dec 29
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Featured Southeast Iowa 4 Stars Hotels

Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 out of 5
4901 Avenue O Fort Madison IA
Free Cancellation
13.56 mi from city center
$66 nightly
The price is $74 total per night
$74 total
Dec 28 - Dec 29
Total with taxes and fees
Cobblestone Inn & Suites - Fort Madison features a gym, free WiFi in public areas, and meeting rooms. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Breakfast included
Parking included
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

2.5 out of 5
3404 Main St Keokuk IA
Free Cancellation
Reserve now, pay when you stay
22.72 mi from city center
$80 nightly
The price is $90 total per night
$90 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Quality Inn & Suites Keokuk North have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub
Nauvoo Temple House Hotel

Nauvoo Temple House Hotel

2 out of 5
1200 Mulholland St Nauvoo IL
Free Cancellation
Reserve now, pay when you stay
16.25 mi from city center
$88 nightly
The price is $99 total per night
$99 total
Jan 23 - Jan 24, 2026
Total with taxes and fees
Guests of Nauvoo Temple House Hotel enjoy free WiFi in public areas, microwave in a common area, and an ATM. If you decide to drive, there's free parking. Helpful staff is there to provide front-desk service during limited hours, as well as offer insight about the area. This smoke-free hotel also has a gift shop.
Pet friendly
Parking included
AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

2.5 out of 5
628 S Gear Ave West Burlington IA
Free Cancellation
Reserve now, pay when you stay
24.05 mi from city center
$61 nightly
The price is $69 total per night
$69 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of AmericInn by Wyndham West Burlington enjoy an indoor pool, free WiFi in public areas, and conference space. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Other amenities at this family-friendly hotel include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

2 out of 5
1100 N Grand Ave Mount Pleasant IA
Free Cancellation
Reserve now, pay when you stay
18.73 mi from city center
$76 nightly
The price is $85 total per night
$85 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At AmericInn by Wyndham Mount Pleasant, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a business center, coffee/tea in a common area, and free newspapers.
Pool
Breakfast included
Fun City Resort Hotel

Fun City Resort Hotel

3.5 out of 5
3001 Winegard Drive Burlington IA
Free Cancellation
Reserve now, pay when you stay
25.55 mi from city center
$168 nightly
The price is $188 total per night
$188 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Fun City Resort Hotel have access to a casino, a water park, and an indoor pool. There's free parking, as well as a free airport shuttle (available 24 hours). Front-desk staff are standing by 24/7 to assist with any requests. Other amenities at this family-friendly hotel include a lazy river, a 24-hour gym, and free WiFi in public areas.
Pool
Spa
Comfort Suites Burlington

Comfort Suites Burlington

2.5 out of 5
1780 Stonegate Center Dr Burlington IA
Free Cancellation
Reserve now, pay when you stay
24.72 mi from city center
$110 nightly
The price is $124 total per night
$124 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Comfort Suites Burlington, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include a hot tub, a conference center, and a 24-hour business center.
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 out of 5
810 N Grand Avenue Mount Pleasant IA
Free Cancellation
Reserve now, pay when you stay
18.57 mi from city center
$72 nightly
The price is $81 total per night
$81 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Guests staying at Best Western Mt. Pleasant Inn enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include a business center, a computer station, and laundry facilities.
Pool
Breakfast included
Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

2.5 out of 5
325 Main St Keokuk IA
Free Cancellation
Reserve now, pay when you stay
24.97 mi from city center
$57 nightly
The price is $64 total per night
$64 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Baymont by Wyndham Keokuk features an indoor pool, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a banquet hall, a vending machine, and a TV in a common area.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find 4 star hotels in Southeast Iowa

A good hotel meets your expectations, but a great hotel exceeds them. A true 4 star hotel definition includes things like big, comfy beds, stylish décor and friendly service. At Orbitz, we understand that your choice in hotel can make or break an experience, and we are here to help you find the best 4 star hotels for your time in Southeast Iowa. 

What's the difference between a 4 and 5 star hotel?
The difference comes down to level of luxury. While 4 star hotels offer excellent service and quality products, most 5 star hotels will feature complimentary services that go above and beyond, like gourmet dining, luxury spa experiences and poolside service. With 4 star hotels, you’ll find the most comfort without splurging on extras you may not need.

What should I look for in a 4 star hotel?
Southeast Iowa 4 star hotels are likely to include things like:

  • Pool and fitness center
  • Valet parking
  • Room service
  • Dedicated concierge
  • Pillow top mattresses
  • Minibar
  • Bathrobes and bath products
  • Artwork

How do I find the best 4 star hotel?
Orbitz makes finding the best 4 star hotel in Southeast Iowa simple:

  • Pick your price: You’ll find room rates ranging from $64 to $188
  • Get the best quality: 4 star hotels in Southeast Iowa have an average rating of 0.0
  • Read the reviews: Read through reviews to help you choose the hotel that has everything you want

Southeast Iowa hotels essential information

Accommodation
210 hotels
Lowest Price
$64
Highest Price
$188
Popular hotels
Cobblestone Inn & Suites - Fort Madison, Quality Inn & Suites Keokuk North, Nauvoo Temple House Hotel, AmericInn by Wyndham West Burlington, AmericInn by Wyndham Mount Pleasant, Fun City Resort Hotel, Comfort Suites Burlington, Best Western Mt. Pleasant Inn, Baymont by Wyndham Keokuk

Recent Reviews

AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

5/5 Excellent
"Very nice and clean room"
A verified traveler stayed at AmericInn by Wyndham West Burlington
Posted 3 days ago
AmericInn by Wyndham West Burlington

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