Hotels in Upstate South Carolina

Search over 3,090 hotels from $67

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Sep 28 - Sep 29
Tonight
Check prices in Upstate South Carolina for tonight, Sep 28 - Sep 29
Sep 29 - Sep 30
Tomorrow night
Check prices in Upstate South Carolina for tomorrow night, Sep 29 - Sep 30

Top Rated Upstate South Carolina Hotels

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
6.72 mi from city center
$82 nightly
The price is $91 total per night
$91 total
Oct 18 - Oct 19
Total with taxes and fees
At Hyatt Place Greenville/Haywood, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
6.7 mi from city center
$117 nightly
The price is $129 total per night
$129 total
Oct 11 - Oct 12
Total with taxes and fees
Renovated in 2023, Hilton Greenville offers a 24-hour gym, free WiFi in public areas, and meeting rooms. Self parking is available for USD 10 per night. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Other amenities at this family-friendly hotel include a conference center, coffee/tea in a common area, and a computer station.
Pet friendly
Free WiFi
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.61 mi from city center
$108 nightly
The price is $120 total per night
$120 total
Oct 4 - Oct 5
Total with taxes and fees
At Embassy Suites Greenville Golf Resort & Conference Center, guests enjoy a golf course, an indoor pool, and an outdoor pool. If you drive, self parking is USD 10 per day, or you can take advantage of the free airport shuttle during limited hours. The front desk has multilingual staff on hand 24/7 to help with concierge services, dry cleaning/laundry, and securing valuables. Other amenities at this golf resort include a 24-hour gym, free WiFi in public areas, and an outdoor tennis court.
Pool
Breakfast included
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Free Cancellation
5.11 mi from city center
$99 nightly
The price is $110 total per night
$110 total
Oct 18 - Oct 19
Total with taxes and fees
At Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available on request). The front desk has multilingual staff on hand 24/7 to help with securing valuables, concierge services, and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Free airport shuttle
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.51 mi from city center
$401 nightly
The price is $441 total per night
$441 total
Oct 4 - Oct 5
Total with taxes and fees
Guests staying at Grand Bohemian Lodge Greenville, Autograph Collection enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this spa hotel include meeting rooms, conference space, and a business center.
Spa
Pet friendly
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.18 mi from city center
$76 nightly
The price is $84 total per night
$84 total
Oct 18 - Oct 19
Total with taxes and fees
Best Western Plus Greenville I-385 Inn & Suites features a gym, free WiFi in public areas, and a business center. If you drive, put free parking to good use. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.03 mi from city center
$208 nightly
The price is $228 total per night
$228 total
Oct 4 - Oct 5
Total with taxes and fees
Guests of Hotel Hartness have access to a full-service spa, a 24-hour gym, and meeting rooms. If you drive, put free parking to good use. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, concierge services, and dry cleaning/laundry. Other amenities at this spa hotel include conference space, a seasonal outdoor pool, and free use of bicycles.
Pool
Spa
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
8.73 mi from city center
$160 nightly
The price is $176 total per night
$176 total
Oct 13 - Oct 14
Total with taxes and fees
Guests staying at Mint House Greenville Downtown by Kasa enjoy a 24-hour gym, express check-in, and express check-out. Self parking is available for USD 10 per night. This apartment building also has laundry facilities.
Kitchen
Washer
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Free Cancellation
Reserve now, pay when you stay
31.57 mi from city center
$105 nightly
The price is $117 total per night
$117 total
Oct 4 - Oct 5
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center features a 24-hour gym, free WiFi in public areas, and meeting rooms. You can put free parking to good use if you drive. Multilingual staff at the 24-hour front desk can assist with securing valuables, dry cleaning/laundry, and concierge services. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Pool
Breakfast included
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.51 mi from city center
$131 nightly
The price is $144 total per night
$144 total
Oct 4 - Oct 5
Total with taxes and fees
At Hyatt Place Greenville Downtown, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 28 per night. The front desk is staffed 24 hours a day to help with luggage storage and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and express check-out.
Pool
Breakfast included
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3 out of 5
11 Ketron Court Greenville SC
4.72 mi from city center
$114 nightly
The price is $125 total per night
$125 total
Oct 4 - Oct 5
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. features free WiFi in public areas, a 24-hour business center, and coffee in a common area. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a computer station, laundry facilities, and barbecue grills.
Breakfast included
Pet friendly
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
33.51 mi from city center
$123 nightly
The price is $135 total per night
$135 total
Sep 29 - Sep 30
Total with taxes and fees
Guests staying at Lakeside Lodge Clemson enjoy a 24-hour gym, free WiFi in public areas, and a hot tub. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with concierge services and securing valuables. Additional amenities include a seasonal outdoor pool and a banquet hall.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
See properties

Cheap Upstate South Carolina hotels options

    Baymont by Wyndham Anderson Clemson

    Baymont by Wyndham Anderson Clemson

    128 Interstate Blvd Anderson SC
    $64 nightly
    The price is $71 total per night from Oct 5 to Oct 6
    $71 total
    Oct 5 - Oct 6
    Total with taxes and fees
    7/10 Good! (920 reviews)
    Days Inn by Wyndham Greenville

    Days Inn by Wyndham Greenville

    60 Roper Mountain Rd Greenville SC
    $61 nightly
    The price is $67 total per night from Oct 4 to Oct 5
    $67 total
    Oct 4 - Oct 5
    Total with taxes and fees
    Baymont by Wyndham Greenville Woodruff Rd

    Baymont by Wyndham Greenville Woodruff Rd

    31 Old Country Rd Greenville SC
    $68 nightly
    The price is $75 total per night from Oct 4 to Oct 5
    $75 total
    Oct 4 - Oct 5
    Total with taxes and fees
    Red Roof Inn Spartanburg – I-26

    Red Roof Inn Spartanburg – I-26

    6765 Pottery Rd Spartanburg SC
    $61 nightly
    The price is $68 total per night from Oct 13 to Oct 14
    $68 total
    Oct 13 - Oct 14
    Total with taxes and fees
    7/10 Good! (782 reviews)
    Quality Inn & Suites Greenville near downtown

    Quality Inn & Suites Greenville near downtown

    10 Mills Ave Greenville SC
    $71 nightly
    The price is $78 total per night from Oct 4 to Oct 5
    $78 total
    Oct 4 - Oct 5
    Total with taxes and fees
    7/10 Good! (786 reviews)
    Days Inn by Wyndham Anderson

    Days Inn by Wyndham Anderson

    1007 George Smith Mill Rd Anderson SC
    $61 nightly
    The price is $68 total per night from Oct 11 to Oct 12
    $68 total
    Oct 11 - Oct 12
    Total with taxes and fees
    8.2/10 Very Good! (1,015 reviews)

Upstate South Carolina hotels essential information

Accommodation
3,090 hotels
Lowest Price
$67
Highest Price
$441
Popular hotels
Hyatt Place Greenville/Haywood, Hilton Greenville, Embassy Suites Greenville Golf Resort & Conference Center, Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Grand Bohemian Lodge Greenville, Autograph Collection, Best Western Plus Greenville I-385 Inn & Suites, Hotel Hartness, Mint House Greenville Downtown by Kasa, Best Western Plus Clemson Hotel & Conference Center, Hyatt Place Greenville Downtown, La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd., Lakeside Lodge Clemson

Recent Reviews

Hilton Greenville

Hilton Greenville

4/5 Good
"I had a good stay, clean and friendly.."
A verified traveler stayed at Hilton Greenville
Posted 4 hours ago
Hilton Greenville

More to Explore