Hotels in Upstate South Carolina

Search over 2,949 hotels from $63

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Mar 29 - Mar 30
Tonight
Check prices in Upstate South Carolina for tonight, Mar 29 - Mar 30
Mar 30 - Mar 31
Tomorrow night
Check prices in Upstate South Carolina for tomorrow night, Mar 30 - Mar 31

Top Rated Upstate South Carolina Hotels

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
6.7 mi from city center
$99 nightly
The price is $109 total per night
$109 total
Apr 12 - Apr 13
Total with taxes and fees
Renovated in 2023, Hilton Greenville offers a 24-hour gym, free WiFi in public areas, and meeting rooms. Self parking is available for USD 10 per night. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Other amenities at this family-friendly hotel include a conference center, coffee/tea in a common area, and a computer station.
Pet friendly
Free WiFi
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.61 mi from city center
$98 nightly
The price is $107 total per night
$107 total
Apr 5 - Apr 6
Total with taxes and fees
At Embassy Suites Greenville Golf Resort & Conference Center, guests enjoy a golf course, an indoor pool, and an outdoor pool. If you drive, self parking is USD 10 per day, or you can take advantage of the free airport shuttle during limited hours. The front desk has multilingual staff on hand 24/7 to help with securing valuables, luggage storage, and concierge services. Other amenities at this golf resort include a 24-hour gym, free WiFi in public areas, and an outdoor tennis court.
Pool
Breakfast included
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.51 mi from city center
$349 nightly
The price is $383 total per night
$383 total
Apr 2 - Apr 3
Total with taxes and fees
Guests staying at Grand Bohemian Lodge Greenville, Autograph Collection enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this spa hotel include conference space, coffee/tea in a common area, and a banquet hall.
Spa
Pet friendly
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Free Cancellation
Reserve now, pay when you stay
31.57 mi from city center
$104 nightly
The price is $115 total per night
$115 total
Apr 3 - Apr 4
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center features a 24-hour gym, free WiFi in public areas, and meeting rooms. You can put free parking to good use if you drive. Multilingual staff at the 24-hour front desk can assist with luggage storage, concierge services, and securing valuables. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Pool
Breakfast included
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.03 mi from city center
$209 nightly
The price is $230 total per night
$230 total
Apr 5 - Apr 6
Total with taxes and fees
Guests of Hotel Hartness have access to a full-service spa, a 24-hour gym, and meeting rooms. If you drive, put free parking to good use. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, concierge services, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls and an off-leash area. Other amenities at this spa hotel include conference space, a seasonal outdoor pool, and free use of bicycles.
Pool
Spa
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
6.72 mi from city center
$95 nightly
The price is $105 total per night
$105 total
Apr 2 - Apr 3
Total with taxes and fees
At Hyatt Place Greenville/Haywood, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

3 out of 5
10 Carolina Point Pkwy Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.06 mi from city center
$115 nightly
The price is $126 total per night
$126 total
Apr 4 - Apr 5
Total with taxes and fees
Drury Inn & Suites Greenville features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and conference space.
Pool
Hot Tub
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.78 mi from city center
$149 nightly
The price is $163 total per night
$163 total
Apr 5 - Apr 6
Total with taxes and fees
Hyatt Regency Greenville features a 24-hour gym, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 33 per day. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Pool
Pet friendly
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.18 mi from city center
$85 nightly
The price is $93 total per night
$93 total
Apr 5 - Apr 6
Total with taxes and fees
Best Western Plus Greenville I-385 Inn & Suites features a gym, free WiFi in public areas, and a business center. If you drive, put free parking to good use. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown

3 out of 5
950 South Main Street Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.88 mi from city center
$134 nightly
The price is $147 total per night
$147 total
Apr 5 - Apr 6
Total with taxes and fees
Homewood Suites by Hilton Greenville Downtown features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. Self parking is offered for USD 18 per day. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3 out of 5
11 Ketron Court Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.72 mi from city center
$87 nightly
The price is $95 total per night
$95 total
Mar 31 - Apr 1
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. features free WiFi in public areas, a 24-hour business center, and coffee in a common area. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a computer station, laundry facilities, and a vending machine.
Breakfast included
Pet friendly
Aloft Greenville Downtown

Aloft Greenville Downtown

3 out of 5
5 North Laurens Street Greenville SC
8.79 mi from city center
$130 nightly
The price is $143 total per night
$143 total
Apr 5 - Apr 6
Total with taxes and fees
At Aloft Greenville Downtown, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 10 per day. Front-desk staff can answer questions 24/7, and assist with concierge services, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Pet friendly
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels options

    Baymont by Wyndham Anderson Clemson

    Baymont by Wyndham Anderson Clemson

    128 Interstate Blvd Anderson SC
    $72 nightly
    The price is $80 total per night from Apr 5 to Apr 6
    $80 total
    Apr 5 - Apr 6
    Total with taxes and fees
    7/10 Good! (868 reviews)
    Days Inn by Wyndham Greenville

    Days Inn by Wyndham Greenville

    60 Roper Mountain Rd Greenville SC
    $64 nightly
    The price is $70 total per night from Mar 30 to Mar 31
    $70 total
    Mar 30 - Mar 31
    Total with taxes and fees
    5.6/10 (1,002 reviews)
    Baymont by Wyndham Greenville Woodruff Rd

    Baymont by Wyndham Greenville Woodruff Rd

    31 Old Country Rd Greenville SC
    $65 nightly
    The price is $72 total per night from Apr 6 to Apr 7
    $72 total
    Apr 6 - Apr 7
    Total with taxes and fees
    7/10 Good! (1,007 reviews)
    Red Roof Inn Spartanburg – I-26

    Red Roof Inn Spartanburg – I-26

    6765 Pottery Rd Spartanburg SC
    $57 nightly
    The price is $63 total per night from Apr 21 to Apr 22
    $63 total
    Apr 21 - Apr 22
    Total with taxes and fees
    Quality Inn & Suites Greenville near downtown

    Quality Inn & Suites Greenville near downtown

    10 Mills Ave Greenville SC
    $67 nightly
    The price is $74 total per night from Apr 5 to Apr 6
    $74 total
    Apr 5 - Apr 6
    Total with taxes and fees
    7/10 Good! (736 reviews)
    Days Inn by Wyndham Anderson

    Days Inn by Wyndham Anderson

    1007 George Smith Mill Rd Anderson SC
    $59 nightly
    The price is $65 total per night from Apr 12 to Apr 13
    $65 total
    Apr 12 - Apr 13
    Total with taxes and fees
    8/10 Very Good! (1,006 reviews)

Upstate South Carolina hotels essential information

Accommodation
2,949 hotels
Lowest Price
$63
Highest Price
$383
Popular hotels
Hilton Greenville, Embassy Suites Greenville Golf Resort & Conference Center, Grand Bohemian Lodge Greenville, Autograph Collection, Best Western Plus Clemson Hotel & Conference Center, Hotel Hartness, Hyatt Place Greenville/Haywood, Drury Inn & Suites Greenville, Hyatt Regency Greenville, Best Western Plus Greenville I-385 Inn & Suites, Homewood Suites by Hilton Greenville Downtown, La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd., Aloft Greenville Downtown

Recent Reviews

Hotel Hartness

Hotel Hartness

5/5 Excellent
"Nice property"
A verified traveler stayed at Hotel Hartness
Posted 19 hours ago
Hotel Hartness

More to Explore