Hotels in Upstate South Carolina

Search over 3,050 hotels from $65

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Aug 14 - Aug 15
Tonight
Check prices in Upstate South Carolina for tonight, Aug 14 - Aug 15
Aug 15 - Aug 16
Tomorrow night
Check prices in Upstate South Carolina for tomorrow night, Aug 15 - Aug 16

Top Rated Upstate South Carolina Hotels

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Free Cancellation
5.11 mi from city center
$85 nightly
The price is $94 total per night
$94 total
Sep 13 - Sep 14
Total with taxes and fees
At Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle (available on request). The front desk has multilingual staff on hand 24/7 to help with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Free airport shuttle
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
6.72 mi from city center
$82 nightly
The price is $91 total per night
$91 total
Aug 31 - Sep 1
Total with taxes and fees
At Hyatt Place Greenville/Haywood, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Free Cancellation
Reserve now, pay when you stay
8.78 mi from city center
$157 nightly
The price is $172 total per night
$172 total
Aug 30 - Aug 31
Total with taxes and fees
Hyatt Regency Greenville features a 24-hour gym, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 33 per day. Multilingual staff at the front desk are standing by 24/7 to help with concierge services, securing valuables, and luggage storage. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Pool
Pet friendly
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
8.51 mi from city center
$361 nightly
The price is $396 total per night
$396 total
Sep 6 - Sep 7
Total with taxes and fees
Guests staying at Grand Bohemian Lodge Greenville, Autograph Collection enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this spa hotel include meeting rooms, conference space, and a business center.
Spa
Pet friendly
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
8.51 mi from city center
$135 nightly
The price is $148 total per night
$148 total
Sep 7 - Sep 8
Total with taxes and fees
At Hyatt Place Greenville Downtown, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 28 per night. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and luggage storage. Additional amenities include conference space, a 24-hour business center, and express check-out.
Pool
Breakfast included
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.61 mi from city center
$100 nightly
The price is $111 total per night
$111 total
Aug 30 - Aug 31
Total with taxes and fees
At Embassy Suites Greenville Golf Resort & Conference Center, guests enjoy a golf course, an indoor pool, and an outdoor pool. If you drive, self parking is USD 10 per day, or you can take advantage of the free airport shuttle during limited hours. The front desk has multilingual staff on hand 24/7 to help with luggage storage, concierge services, and securing valuables. Other amenities at this golf resort include a 24-hour gym, free WiFi in public areas, and an outdoor tennis court.
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.03 mi from city center
$200 nightly
The price is $220 total per night
$220 total
Aug 16 - Aug 17
Total with taxes and fees
Guests of Hotel Hartness have access to a full-service spa, a 24-hour gym, and meeting rooms. If you drive, put free parking to good use. Multilingual staff at the front desk are standing by 24/7 to help with concierge services, dry cleaning/laundry, and securing valuables. Other amenities at this spa hotel include conference space, a seasonal outdoor pool, and free use of bicycles.
Pool
Spa
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Free Cancellation
Reserve now, pay when you stay
31.57 mi from city center
$101 nightly
The price is $112 total per night
$112 total
Aug 16 - Aug 17
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center features a 24-hour gym, free WiFi in public areas, and meeting rooms. You can put free parking to good use if you drive. Multilingual staff at the 24-hour front desk can assist with concierge services, securing valuables, and luggage storage. Additional amenities include a conference center, a 24-hour business center, and a seasonal outdoor pool.
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Free Cancellation
Reserve now, pay when you stay
5.18 mi from city center
$83 nightly
The price is $91 total per night
$91 total
Aug 30 - Aug 31
Total with taxes and fees
Best Western Plus Greenville I-385 Inn & Suites features a gym, free WiFi in public areas, and a business center. If you drive, put free parking to good use. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and securing valuables. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
6.7 mi from city center
$106 nightly
The price is $116 total per night
$116 total
Sep 4 - Sep 5
Total with taxes and fees
Renovated in 2023, Hilton Greenville offers a 24-hour gym, free WiFi in public areas, and meeting rooms. Self parking is available for USD 10 per night. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Other amenities at this family-friendly hotel include a conference center, coffee/tea in a common area, and a computer station.
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Free Cancellation
6.47 mi from city center
$89 nightly
The price is $97 total per night
$97 total
Aug 16 - Aug 17
Total with taxes and fees
At Comfort Inn Greenville - Haywood Mall, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

3 out of 5
10 Carolina Point Pkwy Greenville SC
Free Cancellation
Reserve now, pay when you stay
4.06 mi from city center
$115 nightly
The price is $126 total per night
$126 total
Aug 23 - Aug 24
Total with taxes and fees
Drury Inn & Suites Greenville features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and conference space.
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
See properties

Cheap Upstate South Carolina hotels options

    Baymont by Wyndham Anderson Clemson

    Baymont by Wyndham Anderson Clemson

    128 Interstate Blvd Anderson SC
    $72 nightly
    The price is $80 total per night from Aug 20 to Aug 21
    $80 total
    Aug 20 - Aug 21
    Total with taxes and fees
    Days Inn by Wyndham Greenville

    Days Inn by Wyndham Greenville

    60 Roper Mountain Rd Greenville SC
    $61 nightly
    The price is $67 total per night from Aug 30 to Aug 31
    $67 total
    Aug 30 - Aug 31
    Total with taxes and fees
    Baymont by Wyndham Greenville Woodruff Rd

    Baymont by Wyndham Greenville Woodruff Rd

    31 Old Country Rd Greenville SC
    $65 nightly
    The price is $72 total per night from Aug 30 to Aug 31
    $72 total
    Aug 30 - Aug 31
    Total with taxes and fees
    7/10 Good! (1,000 reviews)
    Red Roof Inn Spartanburg – I-26

    Red Roof Inn Spartanburg – I-26

    6765 Pottery Rd Spartanburg SC
    $61 nightly
    The price is $68 total per night from Aug 28 to Aug 29
    $68 total
    Aug 28 - Aug 29
    Total with taxes and fees
    Quality Inn & Suites Greenville near downtown

    Quality Inn & Suites Greenville near downtown

    10 Mills Ave Greenville SC
    $71 nightly
    The price is $79 total per night from Sep 3 to Sep 4
    $79 total
    Sep 3 - Sep 4
    Total with taxes and fees
    Days Inn by Wyndham Anderson

    Days Inn by Wyndham Anderson

    1007 George Smith Mill Rd Anderson SC
    $59 nightly
    The price is $65 total per night from Sep 1 to Sep 2
    $65 total
    Sep 1 - Sep 2
    Total with taxes and fees

Upstate South Carolina hotels essential information

Accommodation
3,050 hotels
Lowest Price
$65
Highest Price
$396
Popular hotels
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Hyatt Place Greenville/Haywood, Hyatt Regency Greenville, Grand Bohemian Lodge Greenville, Autograph Collection, Hyatt Place Greenville Downtown, Embassy Suites Greenville Golf Resort & Conference Center, Hotel Hartness, Best Western Plus Clemson Hotel & Conference Center, Best Western Plus Greenville I-385 Inn & Suites, Hilton Greenville, Comfort Inn Greenville - Haywood Mall, Drury Inn & Suites Greenville

Recent Reviews

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

5/5 Excellent
"The openness and welcoming into the entrance. The bed was extremely comfortable and the breakfast was delicious. Our room was very clean."
A verified traveler stayed at Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Posted 1 hour ago
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

More to Explore