St. Louis Vacation Homes

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Featured Vacation Homes in St. Louis

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in St. Louis

    Clayton Plaza Hotel & Extended Stay

    Clayton Plaza Hotel & Extended Stay

    7750 Carondelet Avenue, St. Louis, MO
    The price is $101 per night from Nov 17 to Nov 18
    $101
    includes taxes & fees
    $86 per night
    Nov 17 - Nov 18
    8.8/10 Excellent! (2,922 reviews)
    Pear Tree Inn St. Louis Airport

    Pear Tree Inn St. Louis Airport

    10810 Pear Tree Ln, St. Ann, MO
    The price is $100 per night from Oct 27 to Oct 28
    $100
    includes taxes & fees
    $85 per night
    Oct 27 - Oct 28
    9.4/10 Exceptional! (2,465 reviews)
    Hyatt Regency St. Louis at The Arch

    Hyatt Regency St. Louis at The Arch

    315 Chestnut St, St. Louis, MO
    The price is $164 per night from Nov 1 to Nov 2
    $164
    includes taxes & fees
    $139 per night
    Nov 1 - Nov 2
    8.4/10 Very Good! (3,439 reviews)

St. Louis Vacation Homes

Book vacation homes in St. Louis
Next time you take a group getaway top St. Louis, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of St. Louis vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every St. Louis vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in St. Louis; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a St. Louis rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to St. Louis is sure to be a winner.

St. Louis Vacation Homes essential information

Accommodation
532 Vacation Homes
Lowest Price
$100
Highest Price
$292
Popular accommodation
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!, Residence on the Roundabout, Amazing, Recently Rehabbed STL Unit in Prime Soulard Location, 713a, Funky mini loft in fox park! Pet friendly!!, TG Sanctuary | Historic 3BR | Private Yard + Den, Modern Family Home , Tower Grove, Two-Story, Cozy Unit for Groups STL side a, Beautiful Tower Grove Unit, Recently Renovated 2S, The St. Charles Guest House, lovely historic home, fun for families and groups