Southern Minnesota Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Southern Minnesota

Don't see what you're looking for?
See all available properties in Southern Minnesota
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Southern Minnesota

    Treasure Island Resort & Casino

    Treasure Island Resort & Casino

    5734 Sturgeon Lake Road Welch MN
    $91 nightly
    The price is $103 total per night from Jun 14 to Jun 15
    $103 total
    Jun 14 - Jun 15
    Total with taxes and fees
    8.6/10 Excellent! (355 reviews)
    Kahler Grand Hotel

    Kahler Grand Hotel

    20 2nd Ave Sw Rochester MN
    $145 nightly
    The price is $167 total per night from Jul 11 to Jul 12
    $167 total
    Jul 11 - Jul 12
    Total with taxes and fees
    8.4/10 Very Good! (2,154 reviews)
    Kahler Inn and Suites - Mayo Clinic Area

    Kahler Inn and Suites - Mayo Clinic Area

    9 3rd Ave Nw Rochester MN
    $159 nightly
    The price is $183 total per night from Jun 14 to Jun 15
    $183 total
    Jun 14 - Jun 15
    Total with taxes and fees
    8/10 Very Good! (1,590 reviews)

Southern Minnesota Vacation Homes

Book vacation homes in Southern Minnesota
Next time you take a group getaway top Southern Minnesota, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Southern Minnesota vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Southern Minnesota vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Southern Minnesota; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Southern Minnesota rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Southern Minnesota is sure to be a winner.

Southern Minnesota Vacation Homes essential information

Accommodation
349 Vacation Homes
Lowest Price
$103
Highest Price
$215
Popular accommodation
Fantastic Large Home Right On Beautiful Lake Pepin! , Magical Nest Hideaway, Near Mayo Clinic 4-Bed w/ Private Deck & Fire Pit, Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown., 1 mi. from Mayo Clinic; Cozy, Clean, Newly renovated late 1800's space with rich wood floors and French doors, Cozy lakefront Log Home. Hot tub, kayak, yard toys, game room. Pontoon for rent., Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester, 5 bedroom/6 bed 2 bath house close to Shattuck St Mary's

More to Explore