Hotels on the Lake in South Carolina Midlands
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Tomorrow night
Check prices in South Carolina Midlands for tomorrow night, Jun 22 - Jun 23Featured South Carolina Midlands Hotels on the Lake

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr Columbia SC
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $109 total per night
$109 total
Jul 12 - Jul 13
Total with taxes and fees
At Hampton Inn Columbia I-26/Harbison Blvd., guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Days Inn by Wyndham Columbia
1144 Bush River Rd Columbia SC
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $75 total per night
$75 total
Jun 24 - Jun 25
Total with taxes and fees
Days Inn by Wyndham Columbia features a gym, free WiFi in public areas, and a business center. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include a seasonal outdoor pool, a terrace, and laundry facilities.
Pool
Breakfast included

Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Jun 25 - Jun 26
Total with taxes and fees
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This hotel also has a vending machine.
Breakfast included
Pet friendly

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane West Columbia SC
$62 nightly
The price is $67 total per night
$67 total
Jun 28 - Jun 29
Total with taxes and fees
Renovated in 2023, Motel 6 West Columbia, SC - Airport offers free WiFi in public areas, coffee in a common area, and laundry facilities. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a picnic area, a vending machine, and barbecue grills.
Pet friendly
Parking included

The Inn at the Crossroads
128 West Main Street Lake City SC
Free Cancellation
Reserve now, pay when you stay
$156 nightly
The price is $175 total per night
$175 total
Jul 21 - Jul 22
Total with taxes and fees
The Inn at the Crossroads features a 24-hour gym, free WiFi in public areas, and a conference center. There's free parking if you drive. The front desk is staffed 24/7 to help with tours or tickets, securing valuables, and luggage storage. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a terrace.
Breakfast included
Parking included

Residence Inn by Marriott Columbia Northwest/Harbison
944 Lake Murray Blvd Irmo SC
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $113 total per night
$113 total
Jun 28 - Jun 29
Total with taxes and fees
At Residence Inn by Marriott Columbia Northwest/Harbison, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. Multilingual staff at the 24-hour front desk can assist with concierge services, dry cleaning/laundry, and securing valuables. Additional amenities include conference space, a 24-hour business center, and a seasonal outdoor pool.
Pool
Breakfast included

Country Inn & Suites by Radisson, Columbia at Harbison, SC
414 Piney Grove Road Columbia SC
$67 nightly
The price is $73 total per night
$73 total
Jun 22 - Jun 23
Total with taxes and fees
Guests of Country Inn & Suites by Radisson, Columbia at Harbison, SC have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Pool
Breakfast included

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $122 total per night
$122 total
Jun 22 - Jun 23
Total with taxes and fees
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and free newspapers.
Pool
Breakfast included

Lexington Expo Hotel by IHG
108 Saluda Pointe Court Lexington SC
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $109 total per night
$109 total
Jul 19 - Jul 20
Total with taxes and fees
Lexington Expo Hotel by IHG features a gym, free WiFi in public areas, and a business center. You can take advantage of free parking if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$121 nightly
The price is $134 total per night
$134 total
Jun 28 - Jun 29
Total with taxes and fees
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pool
Breakfast included

Quality Inn Fort Mill near Carowinds Blvd.
3560 Lakemont Blvd Fort Mill SC
Free Cancellation
$57 nightly
The price is $63 total per night
$63 total
Jul 19 - Jul 20
Total with taxes and fees
Guests of Quality Inn Fort Mill near Carowinds Blvd. enjoy free WiFi in public areas, a seasonal outdoor pool, and a computer station. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with tours/tickets and securing valuables. This hotel also has free newspapers.
Pool
Breakfast included

Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $96 total per night
$96 total
Jul 5 - Jul 6
Total with taxes and fees
At Hilton Garden Inn Columbia/Harbison, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk has multilingual staff on hand 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Pet friendly

Days Inn by Wyndham Lake City
170 S Ron Mcnair Blvd Lake City SC
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $115 total per night
$115 total
Jun 28 - Jun 29
Total with taxes and fees
At Days Inn by Wyndham Lake City, guests have access to free WiFi in public areas, a seasonal outdoor pool, and express check-out. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a terrace, a picnic area, and a vending machine.
Pool
Breakfast included

Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
$105 nightly
The price is $117 total per night
$117 total
Jul 13 - Jul 14
Total with taxes and fees
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Hyatt Place Columbia/Harbison
1130 Kinley Road Irmo SC
Free Cancellation
Reserve now, pay when you stay
$82 nightly
The price is $92 total per night
$92 total
Jul 3 - Jul 4
Total with taxes and fees
At Hyatt Place Columbia/Harbison, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. A stay here includes free parking. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Midlands hotels essential information
Accommodation | 3,277 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $175 |
Popular hotels | Hampton Inn Columbia I-26/Harbison Blvd., Days Inn by Wyndham Columbia, Red Roof Inn Santee, Motel 6 West Columbia, SC - Airport, The Inn at the Crossroads, Residence Inn by Marriott Columbia Northwest/Harbison, Country Inn & Suites by Radisson, Columbia at Harbison, SC, Best Western Plus Santee Inn, Lexington Expo Hotel by IHG, Hampton Inn Santee-I-95, Quality Inn Fort Mill near Carowinds Blvd., Hilton Garden Inn Columbia/Harbison, Days Inn by Wyndham Lake City, Comfort Inn & Suites Santee, Hyatt Place Columbia/Harbison |
Recent Hotels on the Lake Reviews

Tru By Hilton Columbia Downtown
5/5 Excellent
"Everything was outstanding, definitely will stay there again."
A verified traveler stayed at Tru By Hilton Columbia Downtown
Posted 2 hours ago
More to Explore
- 4 Star Hotels in Blythewood
- B&B in Blythewood
- Cabin Rentals in Blythewood
- Extended Stay Hotels in Blythewood
- Business Hotels in Blythewood
- Kid Friendly Hotels in Blythewood
- Hotels with Pool in Blythewood
- Hotels with Free Breakfast in Blythewood
- Hotels with Hot Tubs in Blythewood
- Pet Friendly Hotels in Blythewood
- Spa Resorts & in Blythewood
- Blythewood Hotels
- Vacation Homes in Blythewood
- Rv Parks in Blythewood
- Apartments in Sandwood
- Cheap Hotels in Columbia
- Hotels with Hot Tubs in Columbia
- Columbia Hotels
- Boutique Hotels in Rose Creek
- Luxury Hotels in Rose Creek
- 5 Star Hotels in Woodfield
- Apartments in Woodfield
- Cottages in Woodfield
- Houseboats in Woodfield
- Hotels near Palmetto Falls Water Park
- Beach Resorts & in Melrose Heights
- Hotels with Free Airport Shuttle in Pinehurst
- Luxury Hotels in Pinehurst
- Spa Resorts & in Pinehurst
- Hotels with Suites in Colonial Heights
- Hotels with a Gym in Colonial Heights
- Pet Friendly Hotels in Colonial Heights
- Pet Friendly Hotels in Killian
- Killian Hotels
- Hotels near Columbia Place Mall
- Hotels near Plex Indoor Sports
- Hotels near Fort Jackson
- Apartments in Dentsville
- Cheap Hotels in Dentsville
- Golf Resorts & in Dentsville
- Hotels with Balconies in Dentsville
- Luxury Hotels in Dentsville
- Dentsville Hotels
- Motels in Dentsville
- Hotels near Polo Road Ball Park
- 4 Star Hotels in Elgin
- 5 Star Hotels in Elgin
- Extended Stay Hotels in Elgin
- Hotels with Pool in Elgin
- Elgin Hotels
- Cheap Hotels in Forest Acres
- Apartments in Royal Pines Estates
- Cabin Rentals in Royal Pines Estates
- Condo Rentals in Royal Pines Estates
- Cottages in Royal Pines Estates
- Extended Stay Hotels in Royal Pines Estates
- Hotels with Pool in Royal Pines Estates
- Royal Pines Estates Hotels
- Vacation Homes in Royal Pines Estates
- Hotels near Hilton Field
- Hotels near Village at Sandhill Mall
- Hotels with Free Airport Shuttle in Lyon Street
- 4 Star Hotels in Lake Carolina
- Hotels with Restaurants in Lake Carolina
- Pet Friendly Hotels in Lake Carolina
- Hotels with a Wedding Venue in Lake Carolina
- Extended Stay Hotels in Arcadia Lakes
- Houseboats in Arcadia Lakes
- Adventure Hotels in South Carolina
- Business Hotels in South Carolina
- Hotels with Pool in South Carolina
- Hotels with Balconies in South Carolina
- Hotels with Free Breakfast in South Carolina
- Hotels with Kitchenettes in South Carolina
- Hotels with Waterslides in South Carolina
- Luxury Hotels in South Carolina
- Flights from Helena to Blythewood
- Flights from Chicago to Blythewood
- Flights from Houston to Blythewood
- Flights from Seattle to Blythewood
- Flights from Toronto to Blythewood
- Flights from Charleston to Blythewood
- Flights from Blythewood
- Flights from Syracuse to Blythewood
- Flights from Milwaukee to Blythewood
- Flights from Savannah to Blythewood
- Flights to Columbia
- Flights from Dentsville
- Flights to Elgin
- Flights to South Carolina


