
Santa Ana Vacation Packages
Book a Stay + Flight or Car to save on your trip
Santa Ana Vacation Packages
Santa Ana Vacation Packages
If you want to package your hotel and flight options to save some cash, you're in the right place! Kick back, unwind and let the talented team at Orbitz help you organize an extraordinary Santa Ana escape. If you simply combine your bookings, you'll save up to $374! Simply take your pick of airfares, hotels, rental cars and experiences. And don't forget — you've got lots of flexibility. Customize your trip with 500 airline partners and some 500,000 international hotel options. There are endless possible options when it comes to the places you can go and what you can see. An awe-inspiring escape awaits!
Where is Santa Ana?
Tickets? Got 'em. Suitcase packed? Yep. Wait... where are we going again? Before you jump in the airport taxi, it's good to know where Santa Ana is. It's a neighborhood of Panama City. You'll discover it 2 miles southwest of the downtown area.Places to Visit in Santa Ana
One attraction that's definitely worth stopping by is Metropolitan Cathedral of Panama. It's just around the bend from Santa Ana. Have a ball finding out more about the life sciences as you take in the stimulating exhibits and displays at Museum of Natural Science. Seeking more nearby options? Spend some time reading a good book and taking in the history of Independence Square. But wait, there's more. Palacio de las Garzas will captivate anyone wanting to learn more about the region's political past.
Car Rentals in Santa Ana
Push play on your favorite driving tunes and discover Santa Ana from the freedom of your own wheels. You'll find some of the biggest and best car rentals in Santa Ana on Orbitz. Arriving by plane? Fox Rental Cars at Tocumen International Airport is the best place to make your way to after you escape baggage claim. Budget is located in the heart of the city at Tocumen International Airport. This makes it an easy option for those staying central.
Places to Visit in Santa Ana
One attraction that's definitely worth stopping by is Metropolitan Cathedral of Panama. It's just around the bend from Santa Ana. Have a ball finding out more about the life sciences as you take in the stimulating exhibits and displays at Museum of Natural Science. Seeking more nearby options? Spend some time reading a good book and taking in the history of Independence Square. But wait, there's more. Palacio de las Garzas will captivate anyone wanting to learn more about the region's political past.
Nearest Airports to Santa Ana
Arriving by air? You'll be checking out the sights and sounds of Panama City before long! Situated 13 miles northeast of Santa Ana, Tocumen International Airport (PTY) is the closest terminal.
Popular Places to Visit Near Santa Ana
El Chorrillo and San Felipe are well worth visiting while you are here. El Chorrillo is 0.6 miles away, while San Felipe is 0.6 miles away.
No Cancellation Fees
Need to cancel your booking? Worried about getting slapped with a fee? Well — we don't have one!^ Hopefully, your airline and hotel don't either, but it's a good idea to get in touch with them beforehand to find out.
Top Santa Ana vacation package deals

Hotel Riu Plaza Panama
Jul 1 - Jul 7
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Reviewed on Apr 15, 2025



Central Hotel Panama Casco Viejo
Jul 6 - Jul 13
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Reviewed on Apr 13, 2024
Top rated hotels for your Santa Ana vacation package

Casco View Apartments

Hotel Riu Plaza Panama
