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Book Sanibel, FL Vacations

Save up to $374^ on your trip when booking flight + hotel together

Top Sanibel vacation deals

Song of the Sea
West Wind Inn
Tropical Winds Motel & Cottages
Sundial Beach Resort & Spa

Sanibel Travel Guide

The travel gurus at Orbitz are here to help you combine your flights and hotels to save heaps. Simply pick a deal and start packing for that epic adventure to Sanibel. You'll save up to $369^ if you bundle your bookings. All you've got to do is select your preferred airfares, hotels, experiences and rental cars. But wait, there's even more! With no less than 500,000 worldwide hotels on our database and 500 airline partners, you'll have plenty of flexibility to tailor your trip. There are limitless available room types, flight options and spectacular experiences to satisfy your wandering spirit. Which ones will you decide on?

Where is Sanibel?

An easy, worry-free vacation starts with doing your research. Keep reading to find out just where Sanibel is. It's a neighborhood in the much-loved city of Fort Myers. You'll find it sitting 19 miles to the southwest of the downtown area. There are approximately 62,000 locals that call Fort Myers home.

Places to Visit in Sanibel

Whether you're a nature buff or just looking for a fun way to spend the day, Bailey - Matthews Shell Museum is a great place to visit. Need more? Immerse yourself in history at Sanibel Historical Village and Museum. See artifacts and original buildings and trace the footsteps of people who once ambled down its walkways. Have more time to burn? Sanibel Historical Museum and Village is home to a comprehensive range of historical displays, allowing visitors to uncover the events and stories that formed the region.

Car Rentals in Sanibel

Adventure is fuel for the soul, and the best way to find it is with the freedom of your own ride. See and do more by checking out car rentals in Sanibel with Orbitz. If you're getting in by plane, you can easily pick up your rental vehicle from Southwest Florida International Airport. Dollar Rent A Car is the place to look for. If you're looking to rent a car in Sanibel, you're going to have to head to a nearby neighborhood to get to an outlet. Located at 17811 San Carlos Blvd. in Truckland is Enterprise. Give them a ring and you'll be behind the wheel in no time.

Where to stay in Sanibel – Hotel Accommodation

Orbitz lists 49 hotels in Sanibel. Lock in one of the best options so you can begin planning the rest of your unforgettable adventure. Want a room that's fit for a king? Our top luxurious accommodations are the Sanibel Harbour Marriott Resort & Spa (17260 Harbour Pointe Dr) and the Beach Road Home by RedAwning (928 Beach Road). If you're more of a bargain hunter, check out some of our less-expensive options. You'll have plenty of change bouncing around in your pockets if you book a room at the Tropical Winds Motel & Cottages or the Gulf Breeze Cottages.

Nearest Airports to Sanibel

Unexpected getaways can be thrilling, but it still pays to know something about where you're going. Located 20 miles from Sanibel, Southwest Florida International Airport (RSW) is the most convenient terminal.

Popular Places to Visit Near Sanibel

Why not visit Periwinkle Way? You'f find it just 2 miles away.

No Cancellation Fees

No matter if you've had a change of heart or your plans have shifted for another reason, we won't hit you with a fee if you have to cancel or adjust your booking.^ As we can't say the same for your airline or hotel, it might be a good idea to check with them ASAP.

Top rated hotels for your Sanibel vacation

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top things to do in Sanibel

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