Business Hotels in Northwest Alabama, AL

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Dec 18 - Dec 19
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Dec 19 - Dec 20
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Featured Northwest Alabama Business Hotels

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

2.5 out of 5
1934 Highway 20 Tuscumbia AL
Free Cancellation
Reserve now, pay when you stay
$130 nightly
The price is $142 total per night
$142 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
At Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a 24-hour business center, a meeting room, and a computer station.
Pool
Breakfast included
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $78 total per night
$78 total
Dec 19 - Dec 20
Total with taxes and fees
Guests of Baymont by Wyndham Florence/Muscle Shoals enjoy access to free WiFi in public areas, conference space, and a business center. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Breakfast included
Best Western Plus Russellville Hotel & Suites

Best Western Plus Russellville Hotel & Suites

2.5 out of 5
13770 Highway 43 Russellville AL
Free Cancellation
Reserve now, pay when you stay
$117 nightly
The price is $129 total per night
$129 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
At Best Western Plus Russellville Hotel & Suites, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $115 total per night
$115 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Comfort Suites Florence Shoals Area offers an indoor pool, free WiFi in public areas, and a hot tub. Free parking is available if you drive. The 24-hour front desk has multilingual staff ready to assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, a meeting room, and free newspapers.
Pool
Hot Tub
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Dec 21 - Dec 22
Total with taxes and fees
At Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with concierge services, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Clarion Inn Sheffield Muscle Shoals features a nightclub, karaoke, and an outdoor pool. If you plan to drive, free parking is available. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and concierge services. Additional amenities include a gym, free WiFi in public areas, and meeting rooms.
Pool
Breakfast included
Hampton Inn & Suites Florence-Downtown

Hampton Inn & Suites Florence-Downtown

2.5 out of 5
505 S Court St Florence AL
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $206 total per night
$206 total
Dec 19 - Dec 20
Total with taxes and fees
Guests of Hampton Inn & Suites Florence-Downtown have access to an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and express check-in.
Pool
Breakfast included
Hampton Inn Florence Midtown near University of North Alabama

Hampton Inn Florence Midtown near University of North Alabama

2.5 out of 5
2281 Florence Blvd Florence AL
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $146 total per night
$146 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Hampton Inn Florence Midtown near University of North Alabama have access to an outdoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include conference space, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
Days Inn by Wyndham Moulton

Days Inn by Wyndham Moulton

2 out of 5
12701 Hwy 157 Moulton AL
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $70 total per night
$70 total
Dec 21 - Dec 22
Total with taxes and fees
Days Inn by Wyndham Moulton offers free WiFi in public areas and conference space. Free parking is included with your stay. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Parking included
Hampton Inn Winfield

Hampton Inn Winfield

2.5 out of 5
7005 Highway 129 Winfield AL
Free Cancellation
Reserve now, pay when you stay
$179 nightly
The price is $209 total per night
$209 total
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Winfield features a gym, free WiFi in public areas, and conference space. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and express check-in.
Pool
Breakfast included
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Free Cancellation
$111 nightly
The price is $128 total per night
$128 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and laundry facilities.
Pool
Breakfast included
Renaissance Shoals Resort and Spa

Renaissance Shoals Resort and Spa

3.5 out of 5
10 Hightower Place Florence AL
Free Cancellation
Reserve now, pay when you stay
$249 nightly
The price is $286 total per night
$286 total
Dec 21 - Dec 22
Total with taxes and fees
At Renaissance Shoals Resort and Spa, guests enjoy a full-service spa, an indoor pool, and an outdoor pool. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 20.00 per person roundtrip. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this spa resort include a gym, 2 hot tubs, and meeting rooms.
Pool
Hot Tub
Americas Best Value Inn

Americas Best Value Inn

2 out of 5
14184 Highway 43 Russellville AL
Guests of Americas Best Value Inn enjoy free WiFi in public areas, a hot tub, and a business center. If you drive, take advantage of free parking. This hotel also has laundry facilities.
Hot Tub
Pet friendly
Days Inn by Wyndham Hamilton

Days Inn by Wyndham Hamilton

2 out of 5
1849 Military St Hamilton AL
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $86 total per night
$86 total
Dec 22 - Dec 23
Total with taxes and fees
Guests of Days Inn by Wyndham Hamilton enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include coffee/tea in a common area, laundry facilities, and a vending machine.
Pool
Breakfast included
Econo Lodge Russellville

Econo Lodge Russellville

2.5 out of 5
13600 Highway 43 Russellville AL
Free Cancellation
Reserve now, pay when you stay
$69 nightly
The price is $76 total per night
$76 total
Dec 28 - Dec 29
Total with taxes and fees
At Econo Lodge Russellville, guests have access to free WiFi in public areas, a meeting room, and an arcade/game room. A stay here includes free parking. The 24-hour front desk has staff always at the ready. Additional amenities include a banquet hall and a vending machine.
Pet friendly
Parking included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Northwest Alabama hotels essential information

Accommodation
747 hotels
Lowest Price
$70
Highest Price
$286
Popular hotels
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites, Baymont by Wyndham Florence/Muscle Shoals, Best Western Plus Russellville Hotel & Suites, Comfort Suites Florence Shoals Area, Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals, Clarion Inn Sheffield Muscle Shoals, Hampton Inn & Suites Florence-Downtown, Hampton Inn Florence Midtown near University of North Alabama, Days Inn by Wyndham Moulton, Hampton Inn Winfield, Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG, Renaissance Shoals Resort and Spa, Americas Best Value Inn, Days Inn by Wyndham Hamilton, Econo Lodge Russellville

Recent Business Hotels Reviews

The ColdWater Inn

The ColdWater Inn

5/5 Excellent
"Great atmosphere and a great room at reasonable price. A Gem of a Hotel!"
A verified traveler stayed at The ColdWater Inn
Posted 4 days ago
The ColdWater Inn

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