
Mission District Vacation Packages
Book a Stay + Flight or Car to save on your trip
Mission District Vacation Packages
Mission District Vacation Packages
Now's the time to plan your dream Mission District vacation. Chill out and let the hardworking team at Orbitz bundle up amazing hotel and flight deals for you. If you combine your bookings, you can save up to $374! Simply take your pick of hotels, rental cars, airfares and experiences. Hold on, there's more to come! With no less than 500,000 global hotels on our system and 500 airlines, you've got the chance to make your getaway uniquely yours. Get a package deal that suits you and your distinct style. There are limitless flight options, room types and unforgettable experiences just a click or two away.
Where is Mission District?
You know you want to go there and what you'd like to see, but do you know exactly where Mission District is? Keep reading to find out. It's a neighborhood in the well-loved city of San Francisco. You'll find it located 2 miles to the south of the downtown area. Forget the big-name attractions — it's the locals that make a place tick. Here in San Francisco, you'll discover 800,000 of them.Places to Visit in Mission District
Fans of the big screen will enjoy checking out a screening or two at Castro Theatre. Want more close by options? Are your travel dates flexible? Research what's happening in the next few months at SFJAZZ Center and coincide your stay with an event you're interested in. But wait, there's still more. Easy to spot, Mission Dolores forms a valuable part of the local landscape. This place of worship plays an important role in the religious and social way of life of the area.
Car Rentals in Mission District
Adventure is waiting for you, and there’s no better way to find it than with the freedom of your own ride. See and experience more by checking out car rentals in Mission District with the help of Orbitz. Savvy explorers step off the plane and collect their car within the San Francisco International Airport area. Hertz and Sixt are waiting nearby to help out. Hertz is posiitoned in the center of the city at 1398 Bryant St. If your accommodation is nearby, this is the way to go.
Places to Visit in Mission District
Fans of the big screen will enjoy checking out a screening or two at Castro Theatre. Want more close by options? Are your travel dates flexible? Research what's happening in the next few months at SFJAZZ Center and coincide your stay with an event you're interested in. But wait, there's still more. Easy to spot, Mission Dolores forms a valuable part of the local landscape. This place of worship plays an important role in the religious and social way of life of the area.
Nearest Airports to Mission District
If you're flying in, you'll likely be arriving at San Francisco International Airport (SFO). Grab a coffee and get your bearings after exiting the plane. This is the nearest airport, sitting 10 miles away from the center of Mission District.
Popular Places to Visit Near Mission District
Take the opportunity to explore some nearby destinations such as Castro Street or Castro District. Castro Street is approximately 1 mile from Mission District, while Castro District is 1 mile away.
No Cancellation Fees
Whether you've had a complete turnaround or your plans have veered off-course for a different reason, we won't demand a fee if you need to cancel or revise your booking.^ As we can't say the same for your selected hotel or airline, it's a good idea to check with them ASAP.
Top Mission District vacation package deals

Nob Hill Hotel
Oct 29 - Nov 2
Dallas (DFW) to San Francisco (SFO)
San Francisco (SFO) to Dallas (DFW)
Reviewed on Apr 30, 2025


The Phoenix Hotel
Nov 9 - Nov 15
Dallas (DFW) to San Francisco (SFO)
Reviewed on Nov 24, 2024

Vinarosa Resort & Spa
Nov 14 - Nov 17
Dallas (DFW) to San Francisco (SFO)
Reviewed on May 27, 2024

Marbella Lane Top Coastline Views, Family Friendly
Nov 16 - Nov 22
Baltimore (BWI) to San Francisco (SFO)
San Francisco (SFO) to Baltimore (BWI)
Top rated hotels for your Mission District vacation package

Holiday Inn Golden Gateway by IHG

Hotel Riu Plaza Fisherman's Wharf

Hyatt Regency San Francisco
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