Package deals near Historic Main Street

Save more on your trip when booking your flight + hotel together

Top Historic Main Street vacation deals

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
3.5-star property

The Wildwood Hotel

9.2/10 Wonderful! (1,600 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $326, price is now $172 per person
$172
per person
found 1 day ago
This hotel was fantastic! Check in was easy with friendly staff, the room was beautiful and well appointed. Breakfast was advertised as a Continental, however they had hot options as well, which was great. Every staff member we saw in the hotel said hi and was friendly. I would definitely stay here again!

Reviewed on Oct 16, 2025

Hilton Garden Inn Chesterfield
3.0-star property

Hilton Garden Inn Chesterfield

8.2/10 Very Good! (779 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $249, price is now $174 per person
$174
per person
found 1 day ago
Great stay great service

Reviewed on Apr 8, 2025

The Knight Center at Washington University
2.5-star property

The Knight Center at Washington University

9.4/10 Exceptional! (425 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $286, price is now $203 per person
$203
per person
found 1 day ago
Very nice lobby restaurant and bar

Reviewed on Sep 15, 2025

Hollywood Casino & Hotel St. Louis
3.5-star property

Hollywood Casino & Hotel St. Louis

8.4/10 Very Good! (2,194 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Price was $270, price is now $202 per person
$202
per person
found 1 day ago
Clean rooms, coffee shop is great!

Reviewed on Sep 24, 2025

Ameristar Casino Resort and Spa
4.5-star property

Ameristar Casino Resort and Spa

8.4/10 Very Good! (1,006 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $345, price is now $261 per person
$261
per person
just found
Room was nice. Enjoyed the pool view and spaciousness. Staff was friendly upon arrival and departure.

Reviewed on Dec 2, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0-star property

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center
8.8/10 Excellent! (1,022 reviews)

Jan 17 - Jan 19

2 night stay

Atlanta (ATL) to St. Louis (STL)

Frontier Airlines • Roundtrip • Coach
Price was $252, price is now $191 per person
$191
per person
found 1 day ago
This is a very unique, colorful & artistically interesting property! I would highly recommend and would definitely stay here again!

Reviewed on Sep 9, 2024

Hotel deals near Historic Main Street

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.89 mi from Historic Main Street
$166 nightly
The price is $194 total per night
$194 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Ameristar Casino Resort and Spa have access to a full-service spa, a casino, and a 24-hour gym. The 24-hour front desk has multilingual staff ready to assist with luggage storage and concierge services. Other amenities at this luxury hotel include 2 hot tubs, a conference center, and a seasonal outdoor pool.
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.9 mi from Historic Main Street
$87 nightly
The price is $101 total per night
$101 total
Dec 18 - Dec 19
Total with taxes and fees
At Best Western Plus The Charles Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has multilingual staff ready to assist with luggage storage and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a business center.
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
Free Cancellation
0.62 mi from Historic Main Street
$112 nightly
The price is $128 total per night
$128 total
Dec 28 - Dec 29
Total with taxes and fees
Guests staying at Country Inn & Suites by Radisson, St. Charles Historic District enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with concierge services, luggage storage, and securing valuables. Additional amenities include a library, laundry facilities, and a fireplace in the lobby.
Don't see what you're looking for?
See all available properties in Historic Main Street
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Book a Historic Main Street vacation package

Stop dreaming and start traveling. If you’ve always wanted to see Historic Main Street, now is the perfect time. Book your getaway to St. Louis with Orbitz and get ready to tick this attraction off your bucket list. Plus when you lock in your package with us, you’ll have plenty of cash leftover to splash out on other amazing St. Louis sights. Because travel is all about investing in experiences, not things!

If you’re hoping to stay close to Historic Main Street, we’ve got you covered. Choose from a great range of hotels not far from this attraction. Roll out of bed, slip on your walking shoes and you’ll be there within moments. What could be more convenient than that? You won’t just be close to all the action — you’ll save money on transportation, and a hot shower and cozy bed will be within reach after a big day of exploring. Now that’s what we call a stress- free, full-of-fun getaway.

Orbitz has your ticket to a rewarding Historic Main Street vacation. Book your St. Louis package with us and you’ll be able to access Orbitz Rewards. Earn Orbucks when you reserve your flights, hotels and activities with Orbitz and redeem them at over 385,000 hotels worldwide. $1 Orbuck = $1 off your next hotel. Join, earn, redeem — just like that! When you join Orbitz Rewards, you’ll also instantly unlock exclusive deals and save on thousands of properties with Insider Pricing.

We believe the best reward that you can give to yourself or others is the gift of travel. So, don’t put off exploring Historic Main Street any longer. Save a bundle and book your St. Louis escape with Orbitz today.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.