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Featured Vacation Homes in Hannibal

Mark Twain Lake Hidden Gem~ Perfect Hunters/ Fisherman, and Families~
Mark Twain Lake Hidden Gem~ Perfect Hunters/ Fisherman, and Families~
Center, MO
$110
This vacation home is a smoke-free vacation home.
Quincy Luxury Huge Magnificent Mansion Mississippi River! Christmas Special!
Quincy Luxury Huge Magnificent Mansion Mississippi River! Christmas Special!
Quincy, IL
Guests staying at this vacation home enjoy a water park, an outdoor tennis court, and a garden. This historic vacation home also has barbecue grills.
Only 5 Minutes From Indian Creek Marina at Mark Twain Lake!
Only 5 Minutes From Indian Creek Marina at Mark Twain Lake!
Monroe City, MO
At this vacation home, guests have access to barbecue grills.
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Hannibal Vacation Homes

Book vacation homes in Hannibal
Next time you take a group getaway top Hannibal, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Hannibal vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Hannibal vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Hannibal; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Hannibal rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Hannibal is sure to be a winner.

Hotel Options in Hannibal

See all 42 Properties in Hannibal
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.