Hotels in Louisiana
Search over 83 hotels from $72
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Top Rated Louisiana Hotels

River's Edge Motel

Come see what our Historical town has to offer!

The Eagles Nest Inn

The Yellow Rose Historic Home

Historic rooms near riverfront in downtown, Louisiana, MO

Cozy room located in historic downtown with a 5 minute walk to the riverfront!

Baymont by Wyndham Hannibal

Best Western On The River

Quality Inn & Suites Hannibal

Sleep Inn & Suites

Super 8 by Wyndham Hannibal

Comfort Inn & Suites - Hannibal
How much is a Louisiana hotel?
Check Louisiana hotel room prices by star rating

4 Star Hotels
Top reasons to visit Louisiana
- Historical Charm: Explore Louisiana's rich past at the Louisiana Area Historical Museum, filled with fascinating artifacts and stories.
- Nature's Retreat: Find your peaceful escape amidst Louisiana's picturesque landscapes, perfect for camping and reconnecting with nature.
- Thrilling Adventure: Experience the famous Five-Mile Swing, offering exhilarating rides and breathtaking views for adrenaline junkies.
- Serene River Views: Take a leisurely stroll or enjoy a boat excursion along the Mississippi River, providing a serene setting for relaxation.
- Small-Town Charm: Immerse yourself in the lovely small-town atmosphere of Louisiana, Missouri, with friendly locals and family-friendly activities.
Popular hotels in Louisiana
Planning an outdoor vacation in Louisiana, Missouri? You'll find a range of hotel accommodations to suit every traveler's needs. From cozy and comfortable motel rooms to luxurious hotels with top-notch facilities, Louisiana has it all. Whether you're looking for a budget-friendly option or a high-end luxury experience, you'll find the perfect hotel to suit your preferences. Enjoy your stay in Louisiana and make the most of your outdoor adventures in this beautiful region.
- Quality Inn & Suites Hannibal - This 2.5-star hotel is located 27.3 miles away from Louisiana. With close proximity to the pool, hot tub, and arcade, it offers a fun and relaxing atmosphere. The friendly staff, indoor pool, and complimentary breakfast make it a great choice for your outdoor vacation.
- Best Western On The River - Situated 24.5 miles away from Louisiana, this 2.5-star hotel is perfect for history enthusiasts. It is conveniently located near museums and offers amenities such as a hot tub, indoor pool, and river access. Take advantage of the walking trails and enjoy exciting excursions during your stay.
- Comfort Inn & Suites - Hannibal - Located 24.8 miles away from Louisiana, this 2.5-star hotel offers a range of amenities for a comfortable stay. With an indoor pool, fitness center, and proximity to urban activities, it is ideal for sports and business enthusiasts. Take a dip in the pool and enjoy the convenience of a well-equipped fitness center.
Top things to see and do in Louisiana
Located in Missouri, Louisiana offers a charming escape filled with historical sites, friendly people, and family-friendly activities. History enthusiasts can explore the area's rich past through visits to historical sites such as the Louisiana Area Historical Museum. Nature lovers can find camp spots amidst the picturesque landscapes, perfect for a peaceful getaway. Area attractions include the famous Five-Mile Swing, where visitors can enjoy thrilling rides and breathtaking views. And for those seeking relaxation, the nearby Mississippi River provides a serene setting for leisurely strolls or boat excursions. With its blend of history, natural beauty, and friendly atmosphere, Louisiana is a must-visit destination in Missouri.
- The Eagle's Nest Winery: Indulge in the luxury of The Eagle's Nest Winery, nestled in a small town. Sip on their exquisite selection of wines while enjoying the mesmerizing view of the nearby river. The trendy and relaxing atmosphere makes it perfect for a romantic getaway or a fun excursion with friends. The friendly people and the aroma of freshly brewed coffee add to the charm of this place. Don't miss the chance to experience the opulent opera performances that take place here. A truly unique and unforgettable destination for wine enthusiasts.
Best places to visit in Louisiana
Head to Louisiana, Missouri for an outdoor vacation filled with exciting adventures. Explore the charming streets of Oak St, enjoy the picturesque river views, and experience the lovely small-town atmosphere. With friendly locals and plenty of family-friendly activities, Louisiana is the perfect destination for your outdoor getaway.
- Ashburn: Ashburn, a popular city in Louisiana, offers a unique outdoor experience with its local affinities and vibrant atmosphere. Nestled in the heart of the state, Ashburn boasts stunning natural landscapes, including picturesque bayous and lush forests. Outdoor enthusiasts will find a plethora of activities to indulge in, such as fishing, hiking, and birdwatching. The city also hosts various festivals throughout the year, showcasing the region's rich cultural heritage and lively music scene. Whether you're kayaking along the tranquil waterways or immersing yourself in the lively Cajun culture, Ashburn promises an unforgettable outdoor holiday filled with adventure and authentic Louisiana charm.
Seasonal travel trends of Louisiana
The popularity of Louisiana shows no change throughout the year. The most popular time to visit is between April and June, with a seasonal peak in April. The off-peak tourist season is from November and January, with November typically being the quietest month.
Check out the month-by-month weather chart for Louisiana to help you plan your next trip. With a monthly average of 76.6 degrees Fahrenheit, you can expect the hottest temperatures in July. The coldest month, on average, is January. The most rainfall typically happens in May. Regardless of when you visit Louisiana, every season has a reason to stay.
![]() | ![]() | ![]() | ![]() |
January | 28.6°F (-1.9°C) | Light Rain | Mostly Cloudy |
February | 31.6°F (-0.2°C) | Light Rain | Mostly Sunny |
March | 44.1°F (6.7°C) | Light Rain | Mostly Sunny |
April | 53.8°F (12.1°C) | Light Rain | Mostly Sunny |
May | 64.0°F (17.8°C) | Light Rain | Mostly Sunny |
June | 73.8°F (23.2°C) | Light Rain | Mostly Sunny |
July | 76.6°F (24.8°C) | Light Rain | Mostly Sunny |
August | 75.0°F (23.9°C) | Light Rain | Mostly Sunny |
September | 69.1°F (20.6°C) | Light Rain | Mostly Sunny |
October | 56.3°F (13.5°C) | Light Rain | Mostly Sunny |
November | 44.1°F (6.7°C) | Light Rain | Mostly Sunny |
December | 35.1°F (1.7°C) | Light Rain | Mostly Sunny |
What's the best place for a stay in Louisiana?
What are some of the best hotels to stay with the kids in Louisiana?
Come see what our Historical town has to offer! is a B&B offering free WiFi and in-room kitchenettes.
What are the best hotels in downtown Louisiana?
These are some of our travelers' favorite hotels in the center of Louisiana:
- Come see what our Historical town has to offer! is a B&B offering free WiFi and private decks.
- The Eagles Nest Inn is an inn offering free WiFi, free parking, and in-room refrigerators.
Enjoy the natural setting of Louisiana and experience the riverfront.
What are the best hotels to stay near The Eagle's Nest Winery?
There are great times to be had around almost every corner in Louisiana, starting with The Eagle's Nest Winery. This interesting winery is just 4 miles from the city center and a hit with many visitors. Love to stay a stone's throw from it? Easy. River's Edge Motel is 0.4 miles away and a cozy option.
Louisiana hotels essential information
Accommodation | 83 hotels |
---|---|
Lowest Price | $72 |
Highest Price | $314 |
Popular hotels | River's Edge Motel, Come see what our Historical town has to offer!, The Eagles Nest Inn, The Yellow Rose Historic Home, Historic rooms near riverfront in downtown, Louisiana, MO, Cozy room located in historic downtown with a 5 minute walk to the riverfront!, Baymont by Wyndham Hannibal, Best Western On The River, Quality Inn & Suites Hannibal, Sleep Inn & Suites, Super 8 by Wyndham Hannibal, Comfort Inn & Suites - Hannibal |
Booking tips for Louisiana
Booking tips for Louisiana
Find your perfect hotel with Orbitz
We promote inclusive travel by providing options for your next trip. Utilize our filters to discover eco-certified hotels or those that prioritize LGBTQ+ guests. Our custom filters also assist in finding hotels near popular attractions, offering book now, pay later options, and more.
Travel as you are
At Orbitz, we believe in the power of travel to bring people together. With a long-standing commitment to equality and inclusion, we celebrate the unique experiences of all travelers. Our goal is to create a welcoming world where everyone can explore with confidence and joy. We provide tools, such as our LGBTQ-welcoming hotel filter, to ensure you stay where you are celebrated, not just tolerated.
Saving tips for your trip
If you're looking to save money on your trip to Louisiana, consider visiting during the less popular season from November to January. This is a great time to find discounted prices on flights, hotels, and car rentals. While exploring Louisiana, take advantage of the inexpensive local attractions such as visiting the beautiful river, interacting with friendly locals, and enjoying family-friendly excursions. These affordable options will allow you to have a relaxing and budget-friendly experience in Louisiana.
Recent Reviews

River's Edge Motel
Areas Of Louisiana
Hotels Near
Hotel Themes
Flights To
Book on Expedia
Top Trending
- Cape Girardeau Hotels with Hot Tubs
- Columbia Cheap Hotels
- Osage Beach Hotel Deals
- Springfield Waterpark Hotels & Resorts
- Branson Hotels with an Indoor Pool
- Columbia Hotels with Hot Tubs
- Joplin Cheap Hotels
- Springfield Hotel Deals
- Branson Kid Friendly Hotels
- Cape Girardeau Hotel Deals
- Joplin Hotels with Hot Tubs
- Branson Waterpark Hotels & Resorts
- Columbia Hotel Deals
- Springfield Hotels with Hot Tubs
- Branson Hotel Deals
- St. Joseph Hotel Deals
- Branson Cheap Hotels
- Branson Hotels with Hot Tubs
- Branson Casino Resorts & Hotels