$147 Cheap flights to Santa Cruz
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Top places to visit in Santa Cruz
Cheap flights to Santa Cruz from $147 One Way, $294 Round Trip
$294 return flights and $147 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | August 7 to August 10 | $383 |
| UIO | Puerto Baquerizo Moreno | August 9 to August 12 | $394 |
| UIO | Santa Rosa | August 7 to August 11 | $466 |
| GYE | Santa Rosa | August 9 to August 16 | $498 |
| MIA | Puerto Baquerizo Moreno | August 9 to August 15 | $680 |
| LIM | Puerto Baquerizo Moreno | August 8 to August 15 | $741 |
| JFK | Puerto Baquerizo Moreno | August 8 to August 14 | $756 |
| JFK | Santa Rosa | August 7 to August 14 | $789 |
| IAH | Santa Rosa | August 9 to August 13 | $1,238 |
| LAX | Santa Rosa | August 7 to August 16 | $1,456 |
Find The Perfect Hotel For After Your Flight
Score Epic Santa Cruz Accommodation Deals
Hotel Fiesta
Hotel el descanso del Guia
"The hotel staff greeted us with a smile. Our room was clean and over sized. Breakfast was freshly made and served with a smile. I would highly recommend this hotel."
Reviewed on Jul 31, 2026
Finch Bay Galapagos Hotel
"The staff and service are exceptional! The venue cannot be beaten. It’s the only place with a private beach. They have complementary water taxis that take you everywhere. When we got off our boat, they were waiting for us without us, even having to notify them. Definitely would recommend this hotel ..."
Reviewed on Jul 4, 2026
Maidith Galapagos Inn
"The owners of this hotel are absolutely lovely. The take wonderful care of their guests."
Reviewed on Jul 26, 2026
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Santa Cruz
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Low Price Guarantee
Booking your Santa Cruz flights with Orbitz guarantees low prices every day, all day—no matter when and where you book. You will always find the best deals available, coupled with extra great savings and discounts for all around great value.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.