$149 Cheap flights to Santa Cruz
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Top places to visit in Santa Cruz
Cheap flights to Santa Cruz from $149 One Way, $298 Round Trip
$298 return flights and $149 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | September 20 to September 25 | $313 |
| UIO | Puerto Baquerizo Moreno | September 20 to September 23 | $352 |
| UIO | Santa Rosa | September 18 to September 25 | $382 |
| GYE | Santa Rosa | September 18 to September 20 | $384 |
| LIM | Puerto Baquerizo Moreno | September 18 to September 22 | $532 |
| LIM | Santa Rosa | September 18 to September 22 | $565 |
| MIA | Puerto Baquerizo Moreno | September 18 to September 20 | $811 |
| JFK | Santa Rosa | September 20 to September 29 | $829 |
| JFK | Puerto Baquerizo Moreno | September 20 to September 24 | $965 |
Find The Perfect Hotel For After Your Flight
Score Epic Santa Cruz Accommodation Deals
Hotel Fiesta
"Great stay. The room wasn't big but had an open closet to put some of your stuff and a good amount of storage like drawers etc. The bed was very comfortable. I picked this hotel because they had a nice pool and jacuzzi which did not disappoint. The jacuzzi wasn't very hot though probably like 96 ..."
Reviewed on Sep 12, 2026
Finch Bay Galapagos Hotel
Maidith Galapagos Inn
"Staff are super helpful and friendly, location is good, breakfast is varied and tasty, beds are comfortable. Only downside is the lights are bright white in the rooms."
Reviewed on Sep 15, 2026
Hotel el descanso del Guia
"Muy lejos del centro"
Reviewed on Sep 12, 2026
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
Santa Cruz
Snag some “suite” deals when you add cheap hotel rooms to Santa Cruz flights at Orbitz. You can score tickets to ballgames, concerts and other activities while planning your low fare flights. For non-stop air tickets or planned layovers, Orbitz is your discount travel resource.
Budget Prices, Luxury Life
Find mobile-only bargains on your home away from home with Orbitz cutting-edge mobile tools. Search domestic and international hotels at Orbitz On the Go. Find free travel planning apps for your iPhone, Android or iPad. You’ll always get our guaranteed low prices on your favorite hotels and flights to Santa Cruz.
Fun for All
While shopping Orbitz sales on Santa Cruz flights, remember to throw in some fun. Ticket sales for music, theatre, sports and more can be found on the Activities page. Just tell us what you want to do, and Orbitz will save your seat.
Non-Stop or Stop and Visit
Will you be flying round-trip or one-way? Going directly from Point A to Point B? Maybe you’d like to have dinner with family and friends along the way. Whether you need non-stop flights to {destination.name} or lowest cost layovers on Santa Cruz flights, you will always find the best air travel prices at Orbitz.
All in One
Now you can custom design the perfect travel package with Orbitz and save more when booking your flights to Santa Cruz. Do you have a favorite airline, hotel or car rental company? Every page at Orbitz gives you complete freedom to create your travel plans according to your unique wants and needs. Orbitz is designed to meet your discount travel planning needs completely and conveniently.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.